Vitamin D and Human health, 23 publications in a special issue from 2013

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Citations are as of Oct 2019 – approximately 6 years after publication

Vitamin D and Human Health: Celebrating Diversity

by Simon Spedding
Nutrients 2014, 6(1), 11-14; https://doi.org/10.3390/nu6010011 - 19 Dec 2013  Cited by 4
Abstract This Special Issue of Nutrients: Vitamin D and Human Health celebrates diversity in vitamin D research with articles from bench-to-bedside, examining mechanisms, epidemiology, and clinical issues in the management of non-skeletal disease following themes set by an earlier review in Nutrients [1]. [...] Read more.

The Importance of Dose, Frequency and Duration of Vitamin D Supplementation for Plasma 25-Hydroxyvitamin D

by Yi-Sheng Chao,Ludovic Brunel,Peter Faris andPaul J. Veugelers
Nutrients 2013, 5(10), 4067-4078; https://doi.org/10.3390/nu5104067 - 11 Oct 2013  Cited by 10
Abstract The importance of dose, frequency and duration of vitamin D supplementation for plasma 25(OH)D levels is not well described and rarely reported for supplementation that exceeds 2000 IU per day. The objective is to examine dose, frequency and duration of supplementation in relation [...] Read more.

Increased Plasma Concentrations of Vitamin D Metabolites and Vitamin D Binding Protein in Women Using Hormonal Contraceptives: A Cross-Sectional Study

by Ulla K. Møller,Susanna Við Streym,Lars T. Jensen,Leif Mosekilde,Inez Schoenmakers,Shailja Nigdikar andLars Rejnmark
Nutrients 2013, 5(9), 3470-3480; https://doi.org/10.3390/nu5093470 - 05 Sep 2013  Cited by 36
Abstract Use of hormonal contraceptives (HC) may influence total plasma concentrations of vitamin D metabolites. A likely cause is an increased synthesis of vitamin D binding protein (VDBP). Discrepant results are reported on whether the use of HC affects free concentrations of vitamin D [...] Read more.

Association between Subcutaneous White Adipose Tissue and Serum 25-Hydroxyvitamin D in Overweight and Obese Adults

by Brian D. Piccolo,Gregory Dolnikowski,Elias Seyoum,Anthony P. Thomas,Erik R. Gertz,Elaine C. Souza,Leslie R. Woodhouse,John W. Newman,Nancy L. Keim,Sean H. Adams andMarta D. Van Loan
Nutrients 2013, 5(9), 3352-3366; https://doi.org/10.3390/nu5093352 - 26 Aug 2013  Cited by 22
Abstract Cholecalciferol is known to be deposited in human adipose tissue, but it is not known whether 25-hydroxyvitamin D (25(OH)D) is found in detectable concentrations. Therefore, our objective was to determine whether 25(OH)D is detectable in subcutaneous white adipose tissue (SWAT) in overweight and [...] Read more.

A Novel Role for a Major Component of the Vitamin D Axis: Vitamin D Binding Protein-Derived Macrophage Activating Factor Induces Human Breast Cancer Cell Apoptosis through Stimulation of Macrophages

by Lynda Thyer,Emma Ward,Rodney Smith,Maria Giulia Fiore,Stefano Magherini,Jacopo J. V. Branca,Gabriele Morucci,Massimo Gulisano,Marco Ruggiero andStefania Pacini
Nutrients 2013, 5(7), 2577-2589; https://doi.org/10.3390/nu5072577 - 08 Jul 2013  Cited by 22
Abstract The role of vitamin D in maintaining health appears greater than originally thought, and the concept of the vitamin D axis underlines the complexity of the biological events controlled by biologically active vitamin D (1,25(OH)(2)D3), its two binding proteins that are the vitamin [...]

Vitamin D Status Is Associated with Disease Activity among Rheumatology Outpatients

by Zohreh Sabbagh,Janet Markland andHassanali Vatanparast
Nutrients 2013, 5(7), 2268-2275; https://doi.org/10.3390/nu5072268 - 26 Jun 2013  Cited by 13
Abstract The co-existence of high prevalence of vitamin D inadequacy among Canadians and high prevalence of systematic autoimmune rheumatic diseases (SARDs) raise the question on relationship between the two situations. Objective: To determine vitamin D status in known cases of common SARDs and compare [...] Read more.

Vitamin D Levels Are Associated with Cardiac Autonomic Activity in Healthy Humans

by Michelle C. Mann,Derek V. Exner,Brenda R. Hemmelgarn,Darlene Y. Sola,Tanvir C. Turin,Linda Ellis andSofia B. Ahmed
Nutrients 2013, 5(6), 2114-2127; https://doi.org/10.3390/nu5062114 - 10 Jun 2013  Cited by 29
Abstract Vitamin D deficiency (≤50nmol/L 25-hydroxy vitamin D) is a cardiovascular (CV) risk factor that affects approximately one billion people worldwide, particularly those affected by chronic kidney disease (CKD). Individuals with CKD demonstrate abnormal cardiac autonomic nervous system activity, which has been linked to [...] Read more.

Effects of Vitamin D3 and Paricalcitol on Immature Cardiomyocytes: A Novel Role for Vitamin D Analogs in the Prevention of Cardiovascular Diseases

by Stefania Pacini,Gabriele Morucci,Jacopo J. V. Branca,Stefano Aterini,Marcello Amato,Massimo Gulisano andMarco Ruggiero
Nutrients 2013, 5(6), 2076-2092; https://doi.org/10.3390/nu5062076 - 07 Jun 2013  Cited by 7
Abstract Cardiovascular diseases are more prevalent in patients with chronic kidney disease than in the general population and they are considered the leading cause of death in patients with end-stage renal disease. The discovery that vitamin D3 plays a considerable role in cardiovascular [...] Read more.

Vitamin D Insufficiency and Bone Mineral Status in a Population of Newcomer Children in Canada

by Hassanali Vatanparast,Christine Nisbet andBrian Gushulak
Nutrients 2013, 5(5), 1561-1572; https://doi.org/10.3390/nu5051561 - 14 May 2013  Cited by 13
Abstract Background: Low levels of circulating vitamin D are more likely to be found in those with darker skin pigmentation, who live in areas of high latitude, and who wear more clothing. We examined the prevalence of vitamin D deficiency and inadequacy in newcomer [...] Read more.

Higher Serum 25-Hydroxyvitamin D Concentrations Associate with a Faster Recovery of Skeletal Muscle Strength after Muscular Injury

by Tyler Barker,Vanessa T. Henriksen,Thomas B. Martins,Harry R. Hill,Carl R. Kjeldsberg,Erik D. Schneider,Brian M. Dixon andLindell K. Weaver
Nutrients 2013, 5(4), 1253-1275; https://doi.org/10.3390/nu5041253 - 17 Apr 2013  Cited by 47
Abstract The primary purpose of this study was to identify if serum 25-hydroxyvitamin D (25(OH)D) concentrations predict muscular weakness after intense exercise. We hypothesized that pre-exercise serum 25(OH)D concentrations inversely predict exercise-induced muscular weakness. Fourteen recreationally active adults participated in this study. Each subject [...] Read more.

Total Vitamin D Assay Comparison of the Roche Diagnostics “Vitamin D Total” Electrochemiluminescence Protein Binding Assay with the Chromsystems HPLC Method in a Population with both D2 and D3 forms of Vitamin D

by Laila Abdel-Wareth,Afrozul Haq,Andrew Turner,Shoukat Khan,Arwa Salem,Faten Mustafa,Nafiz Hussein,Fasila Pallinalakam,Louisa Grundy,Gemma Patras andJaishen Rajah
Nutrients 2013, 5(3), 971-980; https://doi.org/10.3390/nu5030971 - 22 Mar 2013  Cited by 28
Abstract This study compared two methods of assaying the 25-hydroxylated metabolites of cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2). A fully automated electrochemiluminescence assay from Roche Diagnostics and an HPLC based method from Chromsystems were used to measure vitamin D levels in surplus sera [...] Read more.

The ABC of Vitamin D: A Qualitative Study of the Knowledge and Attitudes Regarding Vitamin D Deficiency amongst Selected Population Groups

by Billie Bonevski,Jamie Bryant,Sylvie Lambert,Irena Brozek andVanessa Rock
Nutrients 2013, 5(3), 915-927; https://doi.org/10.3390/nu5030915 - 15 Mar 2013  Cited by 13
Abstract Objective: In Australia, vitamin D supply in food is limited, and sun exposure is the main source of vitamin D. However skin cancer risk is high, and the need to gain some sun exposure for adequate vitamin D is challenging public health messages [...] Read more.

Pharmacokinetics of High-Dose Weekly Oral Vitamin D3 Supplementation during the Third Trimester of Pregnancy in Dhaka, Bangladesh

by Daniel E. Roth,Abdullah Al Mahmud,Rubhana Raqib,Evana Akhtar,Robert E. Black andAbdullah H. Baqui
Nutrients 2013, 5(3), 788-810; https://doi.org/10.3390/nu5030788 - 12 Mar 2013  Cited by 18
Abstract A pharmacokinetic study was conducted to assess the biochemical dose-response and tolerability of high-dose prenatal vitamin D3 supplementation in Dhaka, Bangladesh (23°N). Pregnant women at 27–30 weeks gestation (n = 28) were randomized to 70,000 IU once + 35,000 IU/week vitamin D3 [...] Read more.

Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws

by Simon Spedding
Nutrients 2014, 6(4), 1501-1518; https://doi.org/10.3390/nu6041501 - 11 Apr 2014  Cited by 102
Abstract Efficacy of Vitamin D supplements in depression is controversial, awaiting further literature analysis. Biological flaws in primary studies is a possible reason meta-analyses of Vitamin D have failed to demonstrate efficacy. This systematic review and meta-analysis of Vitamin D and depression compared studies [...] Read more.

Molecular Link between Vitamin D and Cancer Prevention

by Meis Moukayed andWilliam B. Grant
Nutrients 2013, 5(10), 3993-4021; https://doi.org/10.3390/nu5103993 - 30 Sep 2013  Cited by 96
Abstract The metabolite of vitamin D, 1α,25-dihydroxyvitamin D3 (also known as calcitriol), is a biologically active molecule required to maintain the physiological functions of several target tissues in the human body from conception to adulthood. Its molecular mode of action ranges from immediate [...] Read more.

Vitamin D: Deficiency, Sufficiency and Toxicity

by Fahad Alshahrani andNaji Aljohani
Nutrients 2013, 5(9), 3605-3616; https://doi.org/10.3390/nu5093605 - 13 Sep 2013  Cited by 73
Abstract The plethora of vitamin D studies over the recent years highlight the pleomorphic effects of vitamin D outside its conventional role in calcium and bone homeostasis. Vitamin D deficiency, though common and known, still faces several challenges among the medical community in terms [...] Read more.

Vitamin D Intake and Risk of Type 1 Diabetes: A Meta-Analysis of Observational Studies

by Jia-Yi Dong,Weiguo Zhang,Jiong Jack Chen,Zeng-Li Zhang,Shu-Fen Han andLi-Qiang Qin
Nutrients 2013, 5(9), 3551-3562; https://doi.org/10.3390/nu5093551 - 12 Sep 2013  Cited by 69
Abstract Vitamin D is suggested to have protective effects against type 1 diabetes. However, the results from observational studies have been inconsistent. We aimed to examine their association by conducting a meta-analysis of observational studies. Multiple databases were searched in June 2013 to identify [...] Read more.

The Role of Vitamin D in Blood Pressure, Endothelial and Renal Function in Postmenopausal Women

by Zhao-Min Liu,Jean Woo,Sheng-Hui Wu andSuzanne C. Ho
Nutrients 2013, 5(7), 2590-2610; https://doi.org/10.3390/nu5072590 - 09 Jul 2013  Cited by 19
Abstract Background: Vitamin D is a pro-hormone that plays an essential role in the vasculature and in kidney function. Aims: To review the extra-skeletal effects of vitamin D on blood pressure, endothelial and renal function with emphasis on recent findings in postmenopausal [...] Read more.

Calcidiol Deficiency in End-Stage Organ Failure and after Solid Organ Transplantation: Status quo

by Ursula Thiem,Bartosz Olbramski andKyra Borchhardt
Nutrients 2013, 5(7), 2352-2371; https://doi.org/10.3390/nu5072352 - 01 Jul 2013  Cited by 2
Abstract Among patients with organ failure, vitamin D deficiency is extremely common and frequently does not resolve after transplantation. This review crystallizes and summarizes existing data on the status quo of vitamin D deficiency in patients with organ failure and in solid organ transplant [...] Read more.

The Role of Vitamin D in Hematologic Disease and Stem Cell Transplantation

by Aric C. Hall andMark B. Juckett
Nutrients 2013, 5(6), 2206-2221; https://doi.org/10.3390/nu5062206 - 18 Jun 2013  Cited by 18
Abstract Vitamin D is a steroid hormone with a broad range of biological effects ranging from the classical role as a mediator of calcium and phosphate balance to cellular differentiation and immune modulation. These effects impact normal and dysfunctional hematopoietic and immune function, which [...] Read more.

Vitamin D and the Athlete: Risks, Recommendations, and Benefits

by Dana Ogan andKelly Pritchett
Nutrients 2013, 5(6), 1856-1868; https://doi.org/10.3390/nu5061856 - 28 May 2013  Cited by 46
Abstract Vitamin D is well known for its role in calcium regulation and bone health, but emerging literature tells of vitamin D’s central role in other vital body processes, such as: signaling gene response, protein synthesis, hormone synthesis, immune response, plus, cell turnover and [...] Read more.

Vitamin D and Obesity

by Simon Vanlint
Nutrients 2013, 5(3), 949-956; https://doi.org/10.3390/nu5030949 - 20 Mar 2013  Cited by 131
Abstract Obesity is a significant health problem world-wide, particularly in developed nations. Vitamin D deficiency is pandemic, and has been implicated in a wide variety of disease states. This paper seeks to examine the consistently reported relationship between obesity and low vitamin D concentrations, [...] Read more.

Does Vitamin D Sufficiency Equate to a Single Serum 25-Hydroxyvitamin D Level or Are Different Levels Required for Non-Skeletal Diseases?

by Simon Spedding,Simon Vanlint,Howard Morris andRobert Scragg
Nutrients 2013, 5(12), 5127-5139; https://doi.org/10.3390/nu5125127 - 16 Dec 2013  Cited by 59
Abstract Objective: Clarify the concept of vitamin D sufficiency, the relationship between efficacy and vitamin D status and the role of Vitamin D supplementation in the management of non-skeletal diseases. We outline reasons for anticipating different serum vitamin D levels are required for different [...] Read more.