Oral Contraceptives Reduce Risk for Ovarian and Endometrial Cancers New York Times Jan 2018
- “ . . the effect is especially evident in smokers, the obese and those who exercise infrequently. .
These people are at high risk of being Vitamin D deficient
- “… those who had used them for 10 years or more had a 34 percent reduced risk for endometrial cancer…”
- “Contraceptive use did not seem to affect the risk for postmenopausal colorectal or breast cancer.”
Results (from the JAMA abstract) doi:10.1001/jamaoncol.2017.4942
The analytic population was aged 50 to 71 years (median, 62 years) at enrollment and largely white (91%) and postmenopausal (96%). For
- ovarian cancer, OC use–associated risk reductions strengthened with duration of use (long-term OC use [≥10 years] HR, 0.60; 95% CI, 0.47-0.76; P < .001 for trend) and were similar across modifiable lifestyle factors.
- Risk reductions for endometrial cancer strengthened with duration of use (long-term OC use HR, 0.66; 95% CI, 0.56-0.78; P < .001 for trend);
- the most pronounced reductions were among long-term OC users who were
- smokers (HR, 0.47; 95% CI, 0.25-0.88), had
- obese BMIs (0.36; 95% CI, 0.25-0.52), and who
- exercised rarely (HR, 0.40; 95% CI, 0.29-0.56).
- Associations between OC use and breast and colorectal cancers were predominantly null.
Note by VitaminDWikik – breast and colorectal cancers usually do not start until years after contraceptives are stopped
- Ovarian cancer risk increases 27 percent for each 8 ng lower level of Vitamin D – Sept 2016
- Oral contraceptive use associated with higher levels of vitamin D – thesis June 2012
- Estrogen contraception pill doubled the response to 1,000 IU of vitamin D – RCT Sept 2017
- All items in category Iron and Vitamin D
Wonder if the boost in Vitamin D levels is associated with the boost in Iron