Vitamin D deficit is associated with accelerated brain aging in the general population
Psychiatry Res Neuroimaging . 2022 Oct 19;327:111558. doi: 10.1016/j.pscychresns.2022.111558 PDF behind $25 paywall
Jan Terock 1 , Sarah Bonk 2 , Stefan Frenzel 2 , Katharina Wittfeld 3 , Linda Garvert 2 , Norbert Hosten 4 , Matthias Nauck 5 , Henry Völzke 6 , Sandra Van der Auwera 3 , Hans Joergen Grabe 3
Vitamin D deficiency has been associated with reduced neurocognitive functioning and the neurodegenerative processes. However, existing evidence on brain structural correlates of vitamin D deficiency is controversial. We sought to investigate associations of vitamin D levels with imaging patterns of brain aging. In addition, we investigated whether low vitamin D levels were associated with gray matter volumes, whole brain volumes and hippocampus volumes. Structural MRI data and vitamin D levels were obtained in 1,865 subjects from the general population. Linear regressions were applied to investigate the association of vitamin D levels and vitamin D deficiency with imaging derived brain age, total brain, gray matter and hippocampal volumes. Different sets of covariates were included.
Vitamin D deficiency was significantly associated with increased brain age.
Also, linear vitamin D levels were significantly associated with total brain and gray matter volumes, while no significant association with hippocampal volume was found.
Further interaction analyses showed that this association was only significant for male subjects. Our results support previous findings suggesting that vitamin D-deficient individuals have an accelerated brain aging. In addition, associations between vitamin D levels and total brain/ gray matter volumes suggest neuroprotective effects of vitamin D on the brain.
See also VitaminDWiki
Brain and Vitamin D - many studies
Vitamin D reduces hair loss - many studies
See also Google Scholar
- Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness - Mrch 2017 https://doi.org/10.1038/ncomms14694 FREE PDF
- Does D matter? The role of vitamin D in hair disorders and hair follicle cycling - 2010 https://doi.org/10.5070/D38s34p6b7
- Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review Dec, 2021 DOI: 10.7759/cureus.20431 FREE PDF
- Role of vitamin D in hair loss: A short review - Sept 2021 https://doi.org/10.1111/jocd.14421 PDF costs $15 to rent
Note: If I were experiencing male-pattern baldness, I would try applying Vitamin D nanoemulsion topically
I have succesfully used micro- D nanoemlusion for many skin, dental and mouth problems
Had tried 5 other nanoemlusions for inhalation
- Nanoemulsion Vitamin D may be a substantially better form
- Topical Vitamin D provides more benefits than oral sometimes - many studies
Note: Topical vitamin D creams are also avaiable on Amazon