Low 25-Hydroxyvitamin D Concentrations May Explain Atherosclerosis in Ancient and Modern Humans.
Glob Heart. 2015 Mar 26. pii: S2211-8160(14)02709-4. doi: 10.1016/j.gheart.2014.12.001. [Epub ahead of print]
Grant WB San Francisco, CA, USA. Electronic address: wbgrant at infionline.net.
A recent issue of Global Heart contained a set of articles on the prevalence of atherosclerosis in ancient and modern people.
An article by Thomas et al. [1] suggested that chronic inflammation might be an important contributing factor.
It noted that in ancient times, inflammation could be due to microbes and parasites, whereas in modern times, it could be due to chronic systemic inflammatory diseases.
PMID: 26014658
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Cardiovascular category listing hasCardiovascular category is associated with other categories: Diabetes 31, Omega-3 31 , Vitamin K 25 , Intervention 22 . Mortality 20 , Skin - Dark 18 , Magnesium 17 , Calcium 14 , Hypertension 14 , Trauma and surgery 13 , Stroke 13 , Kidney 12 , Metabolic Syndrome 11 , Seniors 10 , Pregnancy 8 as of Aug 2022
- Overview Cardiovascular and vitamin D
- Cardiovascular Disease is treated by Vitamin D - many studies 39+ meta-analyses
- Coronary Artery Disease and Vitamin D - many studies 18+
- Cardiovascular problems reduced by Omega-3 - many studies 34+
- Arteries and Atherosclerosis and Vitamin D - many studies 71+
- Atrial Fibrillation decreased by Vitamin D or Magnesium - many studies 26+
- Statins and Vitamin D - many studies 25+
- Arterial Stiffness and Vitamins – only Vitamin D was found to help – meta-analysis Feb 2022
- Those raising Vitamin D above 30 ng were 1.4 X less likely to die of Heart Attack (VA 19 years) – Oct 2021
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- Sudden Cardiac Arrest – 2.8 X higher risk if low vitamin D – 2019
- Peripheral arterial disease risk is 1.5X higher if low vitamin D – meta-analysis March 2018
- Heart attack ICU costs cut in half by Vitamin D – Oct 2018
- Cardiovascular disease 2.3 X more-likely if poor Vitamin D Receptor – Aug 2022
Cholesterol, Statins
- Cholesterol is needed to produce both Vitamin D and Cortisol
- Overview Cholesterol and vitamin D
- Statins and Vitamin D - many studies statins often reduce levels of vitamin D
- Statin side-effects are reduced by Vitamin D – US patent Application – April 2019
Vitamin K2 may actually clean out the arteries
- Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
- Vitamin D is good, but must balance Vitamins A and K2 to prevent Calcification – Masterjohn Aug 2014
- Overview Vitamin K and Vitamin D
Omega-3 also reduces inflammation
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