Vitamin D Status in Children With Forearm Fractures: Incidence and Risk Factors
. J Am Acad Orthop Surg Glob Res Rev. 2020 Aug;4(8):e2000150-5. doi: 10.5435/JAAOSGlobal-D-20-00150.
Pooya Hosseinzadeh 1, Mahshid Mohseni, Arya Minaie, Gary M Kiebzak
Pages listed in BOTH the categories Falls/Fracture and infants/Children
- Low-energy fractures in children with low vitamin D - many studies
- Low energy bone fractures associated with low vitamin D – Dec 2022
- Increase in children with low vitamin D and with tibia fractures during COVID – June 2022
- Forearm fractures in children having low Vitamin D had 3.8 X higher risk of surgery – Aug 2020
- Vitamin D compliance 3X higher when children with fractures actually knew their low vitamin D level – March 2019
- Forearm fractures in children having low Vitamin D had 1.7X higher risk of surgery – March 2018
- Children with forearm fractures have lower levels of vitamin D – June 2017
- Children with fracture history have lower vitamin D levels (behind paywall) – June 2016
- Bone fractures in children requiring surgery were 55X more likely with low vitamin D – June 2015
- Bone fracture in children 1.8 X more likely if born in winter (low vitamin D) – Dec 2014
Falls and Fractures category contains the following
236 items in FALLS and FRACTURES
- Vitamin D and Calcium cost-effectively reduce falls and fractures – April 2019
- see also Overview Seniors and Vitamin D
- Deaths due to falls doubled in just a decade (age-adjusted, perhaps decreased vitamin D) – June 2019
- Preventing Falls in Older Adults – Vitamin D combination is the best - JAMA Meta-analysis Nov 2017
- Falls cut in half by 100,000 IU vitamin D monthly - RCT 2016
- Falls reduced by a third if achieved 40 ng level vitamin D– RCT Sept 2018
- Note: Took 6 months to get to that level. Most trials last only 3 months
- Vitamin D prevents falls – majority of meta-analyses conclude – meta-meta analysis Feb 2015
- Falls reduced by Vitamin D: 13 percent reduction if more than 700 IU – review of 38 trials – Aug 2022
- Vitamin D and fractures – 24 meta-analyses and counting – Dec 2014
- Low trauma bone fractures in seniors – considering Vitamin D loading dose for all, without testing – Nov 2019
- Vitamin K (any amount and any kind) reduced bone fractures by 24 percent – meta-analysis – May 2019
- Hip fracture in VitaminDWiki title (68 as of Dec 2022) Click here for details
Low-energy fractures in children with low vitamin D - many studies
Download the PDF from VitaminDWiki
Introduction: The association between vitamin D status and fracture characteristics in children remains ambiguous. We hypothesized that vitamin D deficient or insufficient children would have an increased risk of forearm fractures severe enough to require surgical management.
Methods: One hundred children with low-energy forearm fractures were prospectively enrolled from a single hospital. Each participant answered a questionnaire focusing on the risk factors for vitamin D deficiency. Fractures were categorized as requiring nonsurgical or surgical management. Vitamin D status was based on the measurement of 25-hydroxyvitamin D (25(OH)D) concentration obtained during the clinic visit and compared between the two fracture groups.
Results: The cohort exhibited a mean age of 9.8 ± 3.2 years (range: 3-15 years), comprising 65 (65%) men and 35 (35%) women. Overall, mean 25(OH)D was 27.5 ± 8.3 ng/mL. Using the Endocrine Society guidelines, 21% of patients were categorized as "vitamin D deficient" (25(OH)D ≤ 20 ng/mL) and 49% as "vitamin D insufficient" (25(OH)D: 21 to 29 ng/mL). Stratification by intervention revealed a mean 25(OH)D of 23.3 ± 8.8 ng/mL in the surgical group (n = 12) and 28.1 ± 8.1 in the nonsurgical group (n = 88) (P = 0.057). Fifty percent of the surgical group were "vitamin D deficient" compared with 17% of the nonsurgical group (P = 0.017). The relative risk of requiring surgical treatment in children with forearm fracture and vitamin D deficiency (25(OH)D < 20 ng/mL) was 3.8. 25(OH)D level, negatively correlated with body mass index (r = -0.21, P = 0.044); 9 surgical patients were overweight or obese (as defined by the criteria of the Centers for Disease Control and Prevention). 25(OH)D level was significantly lower in non-Caucasians compared with Caucasians (26.0 ± 7.2 versus 32.5 ± 9.9 ng/mL; P = 0.0008).
Discussion: Vitamin D deficiency is common in children with forearm fractures and may be a contributing risk factor for forearm fractures requiring surgical management in children.
Conclusion: Vitamin D deficiency and inefficiency are common in children with low energy forearm fractures, especially in obese children and in fractures requiring surgical treatment.Forearm fractures in children having low Vitamin D had 3.8 X higher risk of surgery – Aug 2020
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