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Vitamin D reduced skeletal pain in 85 percent of the patients – Nov 2012

Is Vitamin D Deficiency associated with Non Specific Musculoskeletal Pain?

Glob J Health Sci. 2012 Nov 11;5(1):107-11. doi: 10.5539/gjhs.v5n1p107.
Abbasi M, Hashemipour S, Hajmanuchehri F, Kazemifar AM.
Metabolic Diseases Research Center, Qazvin University of Medical Science, Qazvin, Iran. Hashemipour.sima at yahoo.com.

BACKGROUNDS: Vitamin D deficiency is common worldwide, including Iran. It has been suggested that vitamin D deficiency is associated with non-specific musculoskeletal pain. The aim of this study is evaluation of the association of musculoskeletal pain with vitamin D deficiency and the response of the patients to vitamin D supplementation.

MATERIALS AND METHODS: Sixty two adult patients with chief complaint of musculoskeletal pain were enrolled in the study. Serum concentrations of 25(OH)D, Calcium, Phosphate, Alkaline Phosphatase and PTH were determined. If there was vitamin D deficiency, oral vitamin D supplementation was given. Assessment of pain and its response to therapy was carried out using Visual assessment score (VAS). SPSS software version 15.0 was used for statistical analyses.

FINDINGS: Most of the patients (95.4%) had vitamin D deficiency.

Pain in 53 patients (85.5%) with responded to the proposed treatment. In responder group post treatment vitamin D concentration was significantly higher than non responder group (60.6±27.6and 39.2±9.6 nmol/l respectively, p<0.01) pretreatment vitamin D and minerals concentrations and pain characteristics did not have significant differences in responder and non responder group.

CONCLUSION: Treatment with vitamin D can relieve the pain in majority of the patients with vitamin D deficiency. Lack of response can be due to insufficient increase in serum vitamin D concentration. Reassessment of serum 25(OH)D concentration is recommended in nonresponsive patients.

PMID: 23283042

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Those whose pain did not go away apparently did not get enough vitamin D, as their serum levels were much lower: 16 ng instead of 24 ng

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Vitamin D reduced skeletal pain in 85 percent of the patients – Nov 2012

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- Overview Pain and Vitamin D Off Topic: 4X increase in Americans taking morphine-type drugs in last decade (consider Vitamin D instead) – Aug 2014 Sleep disorder and nonspecific pain implies low vitamin D, especially if dark skin – March 2013 Lumbar spinal stenosis pain strongly associated with low vitamin D – March 2013 Addictive pain relievers Oxycodone and Percocet (not needed as much if have enough vitamin D?) – July 2014 The new happy pill, vitamin D – Prevention July 2013 Back pain associated with less than 40 ng vitamin D – March 2013 Might Vitamin D be the fountain of youth – June 2013 RADICAL discussion of vitamin D and Nonspecific Musculoskeletal Pain– Nov 2012

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