Toggle Health Problems and D

Vitamin D for Adolescents - review 2019

Vitamin D in Adolescents: A Systematic Review and Narrative
- Synthesis of Available Recommendations - 2019

Journal of Adolescent Health xxx (2019) 1—20 DOI : 10.1016/j.jadohealth.2019.08.025
Magdalini Patseadou, M.D., Ph.D.a,b’ , and Dagmar M. Haller, M.D., Ph.D.a,b

  • a Adolescent and Young Adult Health Clinic, Department of Woman, Child and Adolescent Health, Geneva University Hospitals, Geneva, Switzerland
  • b Primary Care Unit, Faculty of Medicine, University of Geneva, Geneva, Switzerland

Purpose: Practical guidelines help clinicians make their preventive and therapeutic choices and improve care management. Our purpose was to collect and synthesize available recommendations concerning vitamin D in adolescents (aged 10—19 years).

Methods: We searched PubMed, EMBASE, and Cochrane databases from inception to February 5, 2019, for guidance published by different professional associations and governments. We also searched the reference lists of identified recommendations and explored the gray literature using Web search engines. We organized documents by theme: dietary requirements, thresholds, prophylactic supplementation, and treatment of deficiency.

Results: A total of 32 documents were identified. Most of them targeted the general population and not specifically the age group of adolescents. There is a general agreement that adolescents should not have serum 25-hydroxyvitamin D concentrations below 25—30 nmol/L to avoid poor bone health. However, there is lack of consensus on the optimal concentration to aim for, levels varying between 25 nmol/L and 150 nmol/L. Adequate nutritional requirements of vitamin D are also subject to debate with values ranging between 200 lU/d and 1,000 lU/d. The upper tolerable intake is estimated at 4,000 lU/d by all study groups. Certain associations recommend routine vitamin D supplementation in adolescents. The recommended daily preventive doses vary between 400 lU and 4,000 lU, depending on season, skin pigmentation, sun exposure, consumption of vitamin D—fortified foods, body mass index, and coexistence of certain medical conditions. ln case of deficiency, different therapeutic regimens of oral vitamin D are proposed depending on the presence of illness and/or the baseline serum 25-hydroxyvitamin D concentrations. Duration of the treatment varies between 4 weeks and 3 months. A maintenance dose is generally recommended after treatment.

Conclusions: At present, there is no consensus among the different societies about vitamin D needs during adolescence. Stronger, evidence-based guidance is needed to inform clinical practice.
 Download the PDF from VitaminDWiki

Created by admin. Last Modification: Wednesday October 13, 2021 00:27:12 GMT-0000 by admin. (Version 4)
Vitamin D for Adolescents - review 2019        
639 visitors, last modified 13 Oct, 2021,
Printer Friendly Follow this page for updates