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Vitamin A is needed in some 3rd world pregnancies (but not too much) – March 2019

Vitamin A and Pregnancy: A Narrative Review

Nutrients 2019, 11(3), 681; https://doi.org/10.3390/nu11030681
Sabina Bastos Maia 1,2,*, Alex Sandro Rolland Souza 1,3,4, Maria de Fátima Costa Caminha 1,5, Suzana Lins da Silva 1,5, Rachel de Sá Barreto Luna Callou Cruz 6, Camila Carvalho dos Santos 7 and Malaquias Batista Filho 1

Vitamin A category listing has 56 items along with the following map


Some items highlighted by VitaminDWiki in the attached PDF

  • The digestion and absorption of vitamin A are associated with the absorption of lipids. Therefore, critically low dietary fat content (less than 5–10 g/day) or conditions such as pancreatic and hepatic diseases and frequent gastroenteritis that interfere with the digestion or absorption of lipids, resulting in steatorrhea, can interfere with the absorption of vitamin A
  • VAD(Vitamin D Deficiency) is more frequent in the last quarter of pregnancy because of the physiological increase in maternal blood volume and accelerated fetal development in the final phase of pregnancy
  • Pregnant women may be more prone to developing VAD during periods in which there is a shortage of foods rich in vitamin A or in the presence of infections, diabetes mellitus, or gestational diabetes
  • In a meta-analysis, Thurnham et al. concluded that the increase in CRP is associated with a decrease of 25% in the serum retinol level
  • In practice, in areas where night blindness is common, VAD is still often seen as widespread
  • VAD in the second trimester of pregnancy was found to be associated with a three-fold increased risk of schizophrenia and other schizophrenia spectrum disorders in children in a large cohort study including 19,044 live births
  • WHO...During pregnancy, there is an increase of approximately 10% to 20% in the need for vitamin A, with the recommended dose being 800 µg/day. It may be difficult to obtain this dose through diet alone, particularly in populations affected by VAD

 Download the PDF from VitaminDWiki

Vitamin A is a crucial micronutrient for pregnant women and their fetuses. In addition to being essential for morphological and functional development and for ocular integrity, vitamin A exerts systemic effects on several fetal organs and on the fetal skeleton. Vitamin A requirements during pregnancy are therefore greater. Vitamin A deficiency (VAD) remains the leading cause of preventable blindness in the world. VAD in pregnant women is a public health issue in most developing countries. In contrast, in some developed countries, excessive vitamin A intake during pregnancy can be a concern since, when in excess, this micronutrient may exert teratogenic effects in the first 60 days following conception. Routine prenatal vitamin A supplementation for the prevention of maternal and infant morbidity and mortality is not recommended; however, in regions where VAD is a public health issue, vitamin A supplementation is recommended to prevent night blindness. Given the importance of this topic and the lack of a complete, up-to-date review on vitamin A and pregnancy, an extensive review of the literature was conducted to identify conflicting or incomplete data on the topic as well as any gaps in existing data.

Created by admin. Last Modification: Friday March 22, 2019 10:28:28 GMT-0000 by admin. (Version 5)

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11627 Vit A and pregnancy.pdf PDF 2019 admin 22 Mar, 2019 09:56 323.03 Kb 578
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