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Rickets in Japan increased 3 X recently, similar to increases in other countries – June 2017

Vitamin D-Deficient Rickets in Japan.

Glob Pediatr Health. 2017 Jun 1;4:2333794X17711342. doi: 10.1177/2333794X17711342. eCollection 2017.
Itoh M1, Tomio J1, Toyokawa S1, Tamura M1, Isojima T1, Kitanaka S1, Kobayashi Y1.
1 The University of Tokyo, Tokyo, Japan.


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Objectives: Our study aimed to clarify the trend of vitamin D deficiency and rickets diagnosed in the past 10 years.

Methods: This observational study used health insurance claims data from 2005 to 2014. The number of beneficiaries for 2005 and 2014 were 91 617 and 365 800, respectively. We included children aged 0 to 15 years diagnosed with vitamin D deficiency or vitamin D-deficient rickets; those with congenital/secondary rickets and low-birth-weight infants were excluded. We analyzed the number of patients and the temporal trend of these diseases in Japan.

Results: The annual number of patients from 2005 to 2008 was <5. The number of patients in 2009 and 2014 were 3.88 (95% confidence interval = 1.77-7.37) and 12.30/100 000 (95% confidence interval = 8.97-16.46), respectively.

Conclusions: Diagnosed cases of vitamin D deficiency and vitamin D-deficient rickets have apparently increased in Japan. Further studies to identify the trend, cause, and prevention of vitamin D-deficient rickets are necessary.

PMID: 28607944 PMCID: PMC5456026 DOI: 10.1177/2333794X17711342

Created by admin. Last Modification: Tuesday June 20, 2017 13:38:31 GMT-0000 by admin. (Version 2)

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