Toggle Health Problems and D

Less response to 800 IU of Vitamin D by Africans than natives in Finland – RCT March 2018

Vitamin D intake, serum 25-hydroxyvitamin D status and response to moderate vitamin D3 supplementation: a randomised controlled trial in East African and Finnish women

British Journal of Nutrition Vol 119, Issue 4 28 Feb 2018 , pp. 431-441. https://doi.org/10.1017/S000711451700397X
Folasade A. Adebayo (a1), Suvi T. Itkonen (a1), Taina Öhman (a1), Essi Skaffari (a1) ...


Overview Dark Skin and Vitamin D contains the following summary
FACT - - People with dark skins have more health problems and higher mortality rate than those with light skins
FACT - - People with dark skins have low levels of vitamin D
FACT - - People with light skins who have low vitamin D have health problems
OBSERVATION - - The health problems of whites with low level of vitamin D are similar to those with dark skins
CONCLUSION - - People with dark skins have more health problems due to low levels of vitamin D
African American Health Disparities are associated with low Vitamin D - Grant Feb 2021
Low Vitamin D increases health problems - independent of skin color

Dark Skin studies: Pregnancy (28 studies),  Genetics (13 studies),  Vitamin D Binding Protein (8 studies),  Vitamin D Receptor (7 studies),  Diabetes (24 studies),   Cardiovascular (18 studies),  Mortality (12 studies), Intervention (16 studies) Click here to see the studies

Note: 9% of East African candidates were rejected because their initial vitamin D levels were < 12 ng
Note: No apparent indication of obesity in either group
Note: No apparent indication of use of concealing clothing in the East African Women

 Download the PDF from VitaminDWiki

East African



Notice for White vs Dark skin women:

  1. Start at higher level
  2. Got to a higher level
  3. Got to higher level months sooner
  4. 800 IU not much better than 400 IU

Insufficient vitamin D status (serum 25-hydroxyvitamin D (S-25(OH)D)<50 nmol/l) is common among immigrants living at the northern latitudes. We investigated ethnic differences in response of S-25(OH)D to vitamin D3 supplementation, through a 5-month randomised controlled trial, in East African and Finnish women in Southern Finland (60°N) from December 2014 to May 2015. Vitamin D intakes (dietary and supplemental) were also examined. Altogether, 191 subjects were screened and 147 women (East Africans n 72, Finns n 75) aged 21–64 years were randomised to receive placebo or 10 or 20 µg of vitamin D3/d. S-25(OH)D concentrations were assessed by liquid chromatography–tandem MS.

At screening, 56 % of East Africans and 9 % of Finns had S-25(OH)D<50 nmol/l. Total vitamin D intake was higher in East Africans than in Finns (24·2 (sd 14·3) v. 15·2 (sd 13·4) µg/d, P<0·001). Baseline mean S-25(OH)D concentrations were higher in Finns (60·5 (sd=16·3) nmol/l) than in East Africans (51·5 (sd 15·4) nmol/l) (P=0·001). In repeated-measures ANCOVA (adjusted for baseline S-25(OH)D), mean S-25(OH)D increased by 8·5 and 10·0 nmol/l with a 10-µg dose and by 10·7 and 17·1 nmol/l with a 20-µg dose for Finns and East Africans, respectively (P>0·05 for differences between ethnic groups).

In conclusion, high prevalence of vitamin D insufficiency existed among East African women living in Finland, despite higher vitamin D intake than their Finnish peers. Moderate vitamin D3 supplementation was effective in increasing S-25(OH)D in both groups of women, and no ethnic differences existed in the response to supplementation.

Title revision of Dec 2019 caused the visitor count to reset.
There have actually been 5233 visitors to this page since it was originally made

Attached files

ID Name Comment Uploaded Size Downloads
9888 Finn.jpg admin 21 May, 2018 33.39 Kb 764
9887 EA.jpg admin 21 May, 2018 35.18 Kb 738
9886 Finish and East African 400 and 800 IU.pdf admin 21 May, 2018 808.74 Kb 732