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Diabetic Neuropathy treated by Vitamin D – review April 2022

Vitamin D in the Prevention and Treatment of Diabetic Neuropathy

Clin Ther. 2022 Apr 12;S0149-2918(22)00136-9. doi: 10.1016/j.clinthera.2022.03.012
Zsuzsanna Putz 1, Dóra Tordai 2, Noémi Hajdú 2, Orsolya Erzsébet Vági 2, Miklós Kempler 3, Magdolna Békeffy 2, Anna Erzsébet Körei 2, Ildikó Istenes 2, Viktor Horváth 2, Anca Pantea Stoian 4, Manfredi Rizzo 5, Nikolaos Papanas 6, Péter Kempler 2

5 Diabetic Neuropathy interventions

Purpose: Neuropathy is one of the most important complications of diabetes. According to recent advances, vitamin D deficiency might play a role in the development and progression of diabetic neuropathy. Moreover, therapeutic vitamin D supplementation has the potential to improve this condition. The aim of the present review was to summarize new data available in this area.

Methods: The PubMed database was searched for articles written in English and published through September 2021, using combinations of the following key words: vitamin D, diabetes, diabetes mellitus, diabetic neuropathy, polyneuropathy, peripheral neuropathy, cardiac autonomic neuropathy, supplementation, and therapy.

Findings: A number of studies have suggested that vitamin D deficiency can play a significant role in the development of peripheral neuropathy, diabetic foot ulcers, as well as cardiovascular autonomic neuropathy in patients with type 2 diabetes. Vitamin D supplementation might serve as an effective adjuvant therapy for neuropathic pain and may slow or stop the progression of neural damage.

Implications: Vitamin D therapy for diabetic complications could be a reliable option; however, further studies are needed to confirm this notion.
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VitaminDWiki titles containing "Neuropathy" (15 as of April 2022)

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Created by admin. Last Modification: Saturday April 16, 2022 14:31:30 GMT-0000 by admin. (Version 5)

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17439 DN intervention.jpg admin 16 Apr, 2022 14:23 156.35 Kb 162
17438 Diabetic Neuropathy - April 2022.pdf PDF 2022 admin 16 Apr, 2022 14:22 321.91 Kb 98