Mechanisms and Disease Associations

Series: Respiratory Medicine
Litonjua, Augusto A. (Ed.)
2012, 2012, XI, 329 p. 49 illus., 24 in color, $209.00 (Purchase individual chapters $25)

Delivers a concise, evidence-based review of the evidence for the role of vitamin D in various lung disorders

Written by an international group of expert authors to promote international readership
Essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel

Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders.

Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. T

he second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease.

The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel.

Keywords

Airway Smooth Muscle Cells - Asthma - COPD - Cystic FIbrosis - Dendritic Cells - Genetic and Genomic Effects - Innate Immune Response - Lung Development - Respiratory Epithelial Cells - T-Regulatory Cells - Tuberculosis - Viral Infections - Vitamin D - Vitamin D Deficiency

TABLE OF CONTENTS

Section I – Introduction

1 Vitamin D Deficiency: Historical Perspectives; Kumaravel Rajakumar; Michael F. Holick
{See also by Kumaravel Rajakumar}
2 Perspective: Evolution of Human Skin Color: How Low Levels of Vitamin D Drove Natural Selection; Scott T. Weiss

Section II- Vitamin D Mechanisms of Relevance to Lung Diseases

3 Vitamin D and Lung Development in Early Life; John S. Torday
4 Vitamin D and the Innate Immune Response ; Philip Liu, Aria Vazirnia
5 Vitamin D and Regulatory T Cells ; Catherine Hawrylowicz, Zoe Urry, Sarah Dimeloe
6 Dendritic Cell Modulation by the Vitamin D System ; Luciano Adorini, Gilles Laverny, Giuseppe Penna
7 Vitamin D Modulates Airway Smooth Muscle Function ; Audreesh Banerjee, Reynold A. Panettieri, Jr.
8 Genetic and Genomic Effects ; Kelan G. Tantisira

Section III. Disease Associations

9 Acute Respiratory Infections ;Jonathan M. Mansbach, Carlos A. Camargo, Jr.
10 The role of vitamin D in the development, exacerbation, and severity of asthma and allergic diseases; Augusto A. Litonjua
11 Vitamin D and COPD ; Wim Janssens, An Lehouck
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See also VitaminDWiki

• All items Breathing and Vitamin D 453 items
• All items in category Lung Cancer and vitamin D 55 items
• All items in category Cystic Fibrosis and vitamin D 52 items
• All items in category TB and vitamin D 124 items
• Overview TB and Vitamin D
• Overview Asthma and Vitamin D
• Vitamin D, COPD, and Epigenertics – Aug 2011