Methods for Controlled Release Oral Dosage of a Vitamin D Compound
United States Patent Application 20140357603
Download the Patent PDF with text and images from VitaminDWiki.
A few claims and comments by VitaminDWiki follow
Claim 34.
The method of claim 21, wherein the patient has a disease selected from the group consisting of
- cancer, including but not limited to
breast, lung, skin, melanoma, colon, colorectal, rectal, prostate and bone cancer; an - autoimmune disease, including but not limited to
type I diabetes, multiple sclerosis, rheumatoid arthritis, polymyositis, dermatomyositis, scleroderma, fibrosis, Grave's disease, Hashimoto's disease, acute or chronic transplant rejection, acute or chronic graft versus host disease, inflammatory bowel disease, Crohn's disease, systemic lupus erythematosis, Sjogren's Syndrome, eczema and psoriasis, dermatitis, including atopic dermatitis, contact dermatitis, allergic dermatitis, and chronic dermatitis; other - inflammatory diseases, including but not limited to
asthma, chronic obstructive pulmonary disease, polycystic kidney disease, polycystic ovary syndrome, pancreatitis, nephritis, hepatitis, and infection; - hypertension;
- cardiovascular disease, including but not limited to
atherosclerosis, arteriosclerosis, coronary artery disease, cerebrovascular disease, peripheral vascular disease, myocardial infarction, myocardial ischemia, cerebral ischemia, stroke, congestive heart failure, cardiomyopathy, - obesity and other weight disorders; lipid disorders including but not limited to
hyperlipidemia, dyslipidemia including associated diabetic dyslipidemia and mixed dyslipidemia hypoalphalipoproteinemia, hypertriglyceridemia, hypercholesterolemia, and low HDL (high density lipoprotein); - metabolic disorder, including but not limited to
Metabolic Syndrome, Type II diabetes mellitus, Type I diabetes mellitus, hyperinsulinemia, impaired glucose tolerance, and - insulin resistance; diabetic complication, including but not limited to
neuropathy, nephropathy, retinopathy, diabetic foot ulcer and cataracts; - thrombosis; and combinations of any of the foregoing
carcinoma, psoriasis, sarcoidosis, tuberculosis, chronic kidney disease, hypophosphatemic VDRR, vitamin D dependent rickets, anticonvulsant treatment-induced bone disease, fibrogenisis imperfecta ossium, osteitis fibrosa cystica, osteomalacia, osteoporosis, osteopenia, osteosclerosis, renal osteodytrophy, rickets, glucocorticoid antagonism, idopathic hypercalcemia, malabsorption syndrome, steatorrhea, tropical sprue, an autoimmune disorder, and combinations of any of the foregoing.
Claim 35.
The method of claim 21, wherein the patient has a disease selected from the group consisting of hypoparathyroidism, Pseudohypo-parathyroidism, secondary hyperparathyroidism, diabetes. medullary carcinoma, psoriasis, sarcoidosis, tuberculosis, chronic kidney disease, hypophosphatemic VDRR, vitamin D dependent rickets, anticonvulsant treatment-induced bone disease, fibrogenisis imperfecta ossium, osteitis fibrosa cystica, osteomalacia, osteoporosis, osteopenia, osteosclerosis, renal osteodytrophy, rickets, glucocorticoid antagonism, idopathic hypercalcemia, malabsorption syndrome, steatorrhea, tropical sprue, an autoimmune disorder, and combinations of any of the foregoing.
Claim 36.
The method of claim 21, wherein the patient has a disease selected from the group consisting of cancer, dermatological disorders, psoriasis, parathyroid disorders, hyperparathyroidism, secondary hyperparathyroidism, bone disorders, osteoporosis, autoimmune disorders, and combinations thereof.
Observations by VitaminDWiki
- Vitamin D has a half life measured in weeks( vs days or months), so it is not surprising that blood levels of vitamin D decreased three weeks after getting a single dose.
- If a person is taking such a low dose of vitamin D that they need a 50,000 IU does less than once every 2 weeks they can just add the vitamin D powder to food consumed over a weeks of so – example – adding it to jam, fruit juice, . . .