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Review of the Management of Rickets (mainly vitamin D) - Aug 2025


Management of rickets: the new horizons for the pediatrician

J Health Popul Nutr 2025 Aug 26;44(1):310. doi: 10.1186/s41043-025-00885-4.
Rummana Tazia Tonny 1, Ranjit Ranjan Roy 2, Tahmina Jesmin 2, Abdullah Al Mamun 2, Nadira Sultana 2

Rickets is a major public health concern globally. It results from impaired mineralization of the growing bone at its growth plate associated with abnormal calcium and phosphate metabolism. Among different classifications, nutritional deficiency is the commonest variety, and the genetic form of rickets has also been identified frequently in this genomic era. Treatment and management of rickets should be targeted as per type along with the pathogenesis of development of this condition. Management differs for each form of rickets and therapy requires distinct treatment, monitoring and follow-up schedule according to the pattern of response to therapy. The objective of this review is to summarize the treatment and management of different types of rickets in the light of recent guidelines and relevant literature.
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