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Vitamin D for infants – 100,000 IU monthly is better than 400 IU daily – RCT Oct 2020

Effect of vitamin D supplementation as a single dose on the nutritional status of vitamin D

Revista Chilena de Pediatría 2020, 91 (5): 684-690 (study is in Spanish)
Johanna Pacheco-Acosta, Fernando Pizarro

VitaminDWiki

100K was better because more of them have vitamin D levels between 30 and 40 ng

Infant-Child category has 835 items and starts with

Having a good level of vitamin D cuts in half the amount of:

Need even more IUs of vitamin D to get a good level if;

  • Have little vitamin D: premie, twin, mother did not get much sun access
  • Get little vitamin D: dark skin, little access to sun
  • Vitamin D is consumed faster than normal due to sickness
  • Older (need at least 100 IU/kilogram, far more if obese)
  • Not get any vitamin D from formula (breast fed) or (fortified) milk
    Note – formula does not even provide 400 IU of vitamin D daily

Infants-Children need Vitamin D

Better than Daily category listing has 31 items


Items in both categories Infant-Child and Intervention - non daily are listed here:

 Download the PDF from VitaminDWiki
Image

INTRODUCTION: Infants are a group at risk of vitamin D (VD) deficiency. The administration of 400 IU of VD per day during the first year of life does not achieve 100% adherence. A single dose of 100,000 IU of oral VD is safe in newborns.

OBJECTIVE: To compare the effect of oral administration of VD between a single dose of 100,000 IU at one month of age vs daily doses of 400 IU on serum concentrations of VD, at 6 months of age.

SUBJECTS AND METHOD: Randomized clinical trial, without masking. 84 healthy infants were included at 1 month of age, randomized to the study group (SG) receiving a single oral dose of 100,000 IU or to the control group (CG), who received daily oral doses of VD of 400 IU from the 1st to the 6th month of life. At 6 months of life, the serum concentration of VD was determined.

RESULTS: 65 infants completed the study, 36 in SG and 29 in CG. No VD deficiency was found.
VD insufficient was 5.5% and 6.8% in the SG and CG, respectively.
The serum concentration of VD at six months of age was 38.8 ± 5.2 ng/ml and 39.7 ± 6.3 ng/ml for the SG and CG, respectively (NS).

CONCLUSIONS: Supplementation of 100,000 IU of VD at one month age achieves serum concentrations of VD at 6 months of life similar to the administration of daily doses of 400 IU of VD from the 1st to the 6th month.
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A randomized clinical trial was conducted, without blinding, which included 84 healthy infants (42 per group) between August 15, 2015, and July 15, 2016, who attend well-baby checkups at the Padre Vicente Irarrázaval Family Health Center (CESFAM), Santia go (Latitude 33°S). We included full-term newborns between 25 and 45 days of age, fed with exclusive or mainly breast milk, with the written informed consent of their parents or representative of legal age.


Created by admin. Last Modification: Friday June 10, 2022 20:48:29 GMT-0000 by admin. (Version 9)

Attached files

ID Name Comment Uploaded Size Downloads
14840 100K monthly.jpg admin 10 Jan, 2021 28.64 Kb 383
14839 100K English.pdf admin 10 Jan, 2021 511.59 Kb 338