Interactions not in previous version of chart

Less magnesium in food, fish, and meat
More polyunsaturated fats - which decrease vitamin D absorption
People with Alzheimer's and Parkinson's often stay indoors more

CLICK HERE for the main page for this chart

for details, translation, supporting evidence, etc.

$150 which perhaps has 100X more UVB than from the sun - with very very little UVA and visible light

CLICK HERE for on-going details

Oops - lost many email addresses for people getting the this monthly summary

Email Henry Lahore if you want to:

• Subscribe to monthly updates on vitamin D
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Top News

Far more vitamin D publications than other vitamins - Sept 2012

More Vitamin Invervention trials for D than for the total of Vitamins A, C, E, and K
Vitamin D 915 vs 798 = "Vitamin A" 188 + "Vitamin C" 269 + "Vitamin E" 236 + "Vitamin K" 105

TB treatment helped with Vitamin D – RCT Sept 2012
Note: There were 14 TB and Vitamin D Invervention Clinical Trials as of Sept 2012

Multidrug-resistant TB may be reduced with vitamin D – Sept 2012

Vitamin D probably can prevent and treat TB and infectious diseases – 2012

Overweight women lost fat in 12 weeks with just 1000 IU vitamin D daily – Sept 2012 Random Controlled Trial

Weight loss of at least 10 % resulted in 5 ng increase in vitamin D levels – Sept 2012

Prescribing Sunshine - book Aug 2012 great first book to read on Vitamin D

Small for gestational age and insulin at age 6 – Sept 2012

Hypothesis: vitamin D suppresses skin cancer – Sept 2012

Increasing bone mineral density increases breast cancer by at least 2X – Aug 2012

Higher vitamin D in pregnancy resulted in 2X better infant psychomotor and mental scores – Sept 2012

Low vitamin D pregnancy associated with both low birth weight and more weight in child later – July 2012

Vitamin D conferences and special issues - 2013 started by Dr. Grant

80 year olds had better cognition and stood better if high level of vitamin D – Sept 2012

Cerebrovascular disease 40 % less likely if high level of vitamin D – meta-analysis Sept 2012 Strokes, etc

Diabetes 3.5X less likely if more than 25 ng Vitamin D – Sept 2012

African-Americans need only 20 ng of vitamin, not 30 ng, based on iPTH – Sept 2012
Has links to many similar results

Forearm fracture 3.5X more often in black children with low levels of vitamin D – Sept 2012

Pre-cursor of active vitamin D made from plants is better than calcitriol – Sept 2012
Time delay from taking till maximum result in body: 6-12 hours vs 1 hour for calcitriol

Colds not stopped in people who were vitamin D sufficient – RCT Oct 2012 which has the following graph

Work-in-progress at VitaminDWiki

• Tan-through shirts might allow getting vitamin D
• Too much Calcium: Arteries, breast cancer, etc. if lack Vitamin K2
• Fatty Acids may increase levels of active vitamin D
• Vitamin D does NOT continue to accumulate in the body: even toxic amounts dissipate without any intervention in 6 months
• Baldness reduced with Vitamin D (and scalp vibration?)
• Does skin have to be warm to make vitamin D?
• Press Release in October? - Possible sentence
  Just put a reminder on your calendar to take just one pill every two weeks to avoid many diseases
  – at an average cost of less than 2 cents per day.

Previous news Vitamin D News - Aug 2012

Also at VitaminDWiki

• All new web pages
• All recently changed web pages
• Top Vitamin D News - the most recent news is above
• All Vitamin D Overviews
• All categories of Information
• All the ways to search for Vitamin D information on VitaminDWiki
• About us

In Nov 2010 the Institute of Medicine voted that 20 nanograms of vitamin D was enough for BONE health

With the following graph you can see that to protect against bone failure that about 72 nmols is needed

NOT the 50 nmols that the IOM voted for.

hashed lines and red were added by VitaminDWiki

CLICK HERE for details from Nature Magazine - July 2011

By the way - the IOM apparently did not look at any data after mid-2008,

so they missed out on an avalanche of new information: more than the bone benefits from Vitamin D

CLICK HERE for a summary of proof of vitamin D benefits

   generally from Random Controlled Trials with Vitamin D intervention

Vitamin D Recommendations from around the world: both IU and nanograms, which has the following

The MINIMUM recommendation by 25 experts was HIGHER than the Institute of Medicine

A notional graph - which provides an overview of lots of vitamin D reports

People are finding the Vitamin D really helps their pets

Especially those pets at high risk of being vitamin D deficient - similar to list of humans at high risk

• Seniors
• Stay out of the sun
• Do not eat organ meats or lots of fish
• Overweight

Vitamin D for Pets items added in April and May 2012

• Vitamin D for Your Dog – A Beagle’s Happy Days April 2012 by Vitamin D Survivor
  Dog age 10 was in some pain and moving slowly Added 20-40 IU per pound of body weight
  Played with the new puppy and enjoyed another happy 5 years.
• Senior pets rejuvenated with vitamin D
• Anyone Give Vitamin D to Their Dog? PaleoHacks July 2011
  Loads of conflicting information:
    Dogs make it their fur.
      No, they make it in their skin.
        No they don't, they need it in their diets.
          You need to supplement.
            You'd better not supplement.
  Person thought that this was the best answer: Furred animals and vitamin D April 2010
• Fat Soluble Vitamins: A, D, E & K in Dogs
  227 IU of vitamin D per pound of FEED. 10X that much is toxic if given for months
• Vitamin D — for pets, sunlight isn't enough June 2010
  " . . the dog and cat were central figures in the discovery of vitamin D as an essential nutrient. In experiments by Sir Edward Mellanby (1919),"

Overview Veterinary and vitamin D

has details on vitamin D needs for animals and pets such as Reptiles, Turtles, birds, etc.

Note:

1. Vets and the US govt consider that Vitamin D2 should not be given to any primate (we are a primate, right?)
2. Vets give 3X as much vitamin D per pound than the US govt says is needed for animials (or humans)
   But, vets are paid to keep their customers healthy, thus they ignore recommendations which might decrease their income
   Doctors on the other hand . . . .

Vitamin D IS a rat poison Nov 2010 in VERY HIGH doses

Lethal dose which will kill half of the rats (LD-50) = 17 mg/kg of rat = 680,000 IU per kg
Thus for a 100 kg rat (weight of an human adult) the LD-50 would be 68,000,000 IU = lethal

Vitamin D was added and the results were documented

Many were random controlled clinical trials in which not even the doctor knows who gets the vitamin D (or how much)

In two cases the group was large enough (an entire country) that they just documented the without/with = before/after.

Example: Turkey found a 60X decrease in rickets after providing FREE 400 IU of vitamin D for all infants

The following table is a snapshot of the documentation as of June 3, 2012

Health Problem	Reduction	Notes
Hypertension	149 => 142	RCT, mmHg, 2400 IU
Cardiovascular	32%	Death after HF. 1000 IU
Diabetes T1	85%	12000 kids, 2000 IU
Diabetes T2	62%	RCT, CRP reduction, 4000 IU
Back Pain	95%	5000/10000 IU
Influenza	90%	RCT, 2000 IU
Falls	19%	RCT, 1000 IU
Pregnancy risks	50%	RCT, 4000 IU
Rickets	98%	Turkey, 400 IU
Multiple Sclerosis		on-going RCT EVIDIMS 10000 IU
Raynaud's pain	40%	RCT, visual scale, 20000 IU avg
Menstrual Pain	76%	RCT, visual scale, 7000 IU avg
C-section, unplanned	50%	RCT underpowered 4000 IU

There are over 800 Clinical Trials with Vitamin D Intervention as of May 2012

Anticipate that this table will be updated many times in 2012 and 2013 as these trials are finished and published.

CLICK HERE for the latest information and more details

The more vitamin D mom takes, the more benefits for her and the future child.

• The benefits to mom start about 2,000 IU daily average (2000 IU costs less than $15 per year)
• Substantial benefits proven for 4,000 IU taken during pregnancy (fewer complications, lower cost)
• Best benefits at 6,000 IU - this much is also needed if breast feeding without supplementing the infant
• Taking > 2,000 IU raises the cost, primarily due to cost of Co-factors

Vitamin D during pregnancy

$* assumes

• You buy fairly low cost vitamin D and co-factors (more expensive if liquid and/or vegan)
• Using a low cost size of vitamin D - such as 5,000 IU, as often as needed. (50,000 IU costs even less)
  Example: 5000 IU every other day if you only want an average of 2500 IU
• Test vitamin D levels of those moms who are at high risk for being vitamin D deficient
     $30 for a blood test about 6 weeks after starting vitamin D to check that mom is getting enough

The above is the summary of the Overview of Vitamin D for Moms and babies, updated May 1, 2012

CLICK HERE for the entire Overview

A Clinical Review of April 2012

Early lack of vitamin D may trigger autism

Also: Overview Autism and vitamin D has the following graphs

US explosion of Autism: the biggest increase was among blacks

Based on a 2008 study (almost certainly higher rates in 2012)

Autism in Denmark

A sample of previous items: Prenatal vitamins – including vitamin D – reduced autism by 7X in some cases – May 2011

special issue papers which are in VitaminDWiki

• Vitamin D: Its role in disease prevention Introduction to special issue by Dr. Grant
• Vitamin D and difference between cancer in whites and blacks
• Why trials of calcium and vitamin D sometimes fail
• Beneficial effects of UV radiation other than via vitamin D production
• All cause mortality and follow-up time Dr. Grant
• Vitamin D and metabolic syndrome
• Vitamin D associations with erectile dysfunction
• Sepsis associated with low vitamin D
• How to reduce hospital infections with vitamin D

We had been speculating why the medical profession has been so slow to accept vitamin D.
Probable reasons appear to include:

1. Myth: Excess vitamin D will turn the human body into marble
    
2. Reversal of position for many previous supplements.
    
3. Risk being sued if exceed guidelines
    
4. Experts do not agree
    
5. Doctors were rarely been trained in nutrition
    
6. Emphasis on treatment, not prevention
    
7. Doctors often can only prescribe D2 anyway
    
8. Seems like too much of a “wonder drug”
    
9. Fear possible loss of income
    
   "It is difficult to get a man to understand something when his salary is dependent upon his not understanding it”  Upton Sinclair
    

CLICK HERE for updated list, links to proofs, etc.