Vitamin D's potential to reduce the risk of hospital-acquired infections
Dermato-Endocrinology Volume 4, 2012 - Issue 2 Dec 2021 https://doi.org/10.4161/derm.2078
Dima A. Youssef, Tamra Ranasinghe, William B. Grant. Alan N. Peiris
Table of contents
Burden of Hospital-Acquired Infections
Antimicrobial Role of Vitamin D
Use of Vitamin D in Infectious Diseases
Bacteremias and Central Vascular Catheter-Associated Bloodstream Infections
Health Care-Associated Pneumonia and Hospital-Acquired Pneumonia
Clostridium difficile Infections
Catheter-Associated Urinary Tract Infections
Surgical Site Infections
Infections due to Virulent Organisms, such as MRSA
Appropriate Dose of Vitamin D
Clipped from PDF
"To note that most recently, Cannell announced that it has become possible to prescribe vitamin D3, as 50,000 IU once weekly, and it can also be prescribed as once every 2 weeks.118"
Health care–associated and hospital-acquired infections are two entities associated with increased morbidity and mortality. They are highly costly and constitute a great burden to the health care system. Vitamin D deficiency (< 20 ng/ml) is prevalent and may be a key contributor to both acute and chronic ill health. Vitamin D deficiency is associated with decreased innate immunity and increased risk for infections. Vitamin D can positively influence a wide variety of microbial infections.
Herein we discuss hospital-acquired infections, such as pneumonia, bacteremias, urinary tract and surgical site infections, and the potential role vitamin D may play in ameliorating them. We also discuss how vitamin D might positively influence these infections and help contain health care costs. Pending further studies, we think it is prudent to check vitamin D status at hospital admission and to take immediate steps to address existing insufficient 25-hydroxyvitamin D levels.
Download the PDF from VitaminDWiki
See also VitaminDWiki
- 42 studies with GRANT in VitaminDWiki title as of Dec 2022
- Doctors Still Struggle to Diagnose a Condition That Kills More Than Stroke (Sepsis, Vitamin D helps) Oct 2022
- Vitamin D is needed before most surgeries – many studies and RCTs
- Little risk of infection after surgery if have more than 50 ng of vitamin D - 2014
- Surgical Site Infection 4X more likely if low vitamin D – Aug 2019
- Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency and liver failure – Oct 2018
- Hospital Acquired Infection, Mortality, Critically Ill and Vitamin D - 2017
- Superbug (Clostridium difficile) Infections strongly associated with low vitamin D - many studies
- Having less than 15 ng of vitamin D increased risk of hospitalization with infection by 2.8 times – April 2016
1,000 hits for "hospital acquired infections" "vitamin D" Dec 2022
- Vitamin D Status and the Risk for Hospital-Acquired Infections in Critically Ill Adults: A Prospective Cohort Study - April , 2015 https://doi.org/10.1371/journal.pone.0122136 FREE PDF small study
- Vitamin D, Hospital-Acquired Infections and Mortality in Critically Ill Patients: Emerging Evidence - 2017 https://doi.org/10.1007/978-3-319-51908-1_15 book chapter
- An effect of single high dose of vitamin D3 on the risk of nosocomial infections, hospitalization time and mortality in hospitalized elderly population. A preliminary report - Dec 2020 https://doi.org/10.36553/wm.56
- One dose of 60,000 IU reduced incidence of Clostridium difficile infection RCT
- Relationship Between Preoperative 25-Hydroxy Vitamin D and Surgical Site Infectiom - Jan 2020 https://doi.org/10.1016/j.jss.2019.07.036