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Vitamin D helps treat Osteoporosis – Sept 2018

Role of nutritional vitamin D in osteoporosis treatment.

Clin Chim Acta. 2018 Sep;484:179-191. doi: 10.1016/j.cca.2018.05.035. Epub 2018 May 18.
Hou YC1, Wu CC2, Liao MT3, Shyu JF4, Hung CF5, Yen TH6, Lu CL7, Lu KC8.

VitaminDWiki

Overview Osteoporosis and vitamin D contains the following summary

  • FACT: Bones need Calcium (this has been known for a very long time)
  • FACT: Vitamin D improves Calcium bioavailability (3X ?)
  • FACT: Should not take > 750 mg of Calcium if taking lots of vitamin D (Calcium becomes too bio-available)
  • FACT: Adding vitamin D via Sun, UV, or supplements increased vitamin D in the blood
  • FACT: Vitamin D supplements are very low cost
  • FACT: Many trials, studies. reviews, and meta-analysis agree: adding vitamin D reduces osteoporosis
  • FACT: Toxic level of vitamin D is about 4X higher than the amount needed to reduce osteoporosis
  • FACT: Co-factors help build bones.
  • It appears that to TREAT Osteoporosis:
  •        Calcium OR vitamin D is ok
  •        Calcium + vitamin D is good
  •        Calcium + vitamin D + other co-factors is great
  • CONCLUSION: To PREVENT many diseases, including Osteoporosis, as well as TREAT Osteoporosis
  • Category Osteoporosis has 172 items
  • Category Bone Health has 240 items

Osteoporosis category includes the following

Pages in BOTH the categories Osteoporosis and Meta-analysis

https://vitamindwiki.com/tiki-editpage.php?page=Osteoporosis
Pages listed in BOTH of the categories Genetics and Osteoporosis

20 Most-visited pages in Osteoporosis category in VitaminDWiki

Id Page Hits Last modification Creator Categories
2095 Quick, free, self test of vitamin D deficiency 130557
21 Oct, 2018 16:12
admin Deficiency of Vitamin D
Tests for Vitamin D
Osteoporosis
Predict Vitamin D
1344 Overview Fractures and vitamin D 45747
25 Nov, 2017 13:59
admin Bone - Health
Osteoporosis
Vitamin D and Calcium
Overviews
Falls and Fractures
1328 Overview Osteoporosis and vitamin D 29364
22 Feb, 2018 19:48
admin Bone - Health
Osteoporosis
Vitamin D and Calcium
Overviews
3424 Osteoporosis 21184
11 Dec, 2018 23:08
ricks99 Osteoporosis
Category
2126 Osteoporosis increasing and vitamin D decreasing in Middle East - Oct 2011 12299
25 Dec, 2011 12:22
admin Osteoporosis
Middle East
2366 Vitamin D, K2, Magnesium, etc increase bone density when taking together– Jan 2012 11812
28 Nov, 2013 17:20
admin Bone - Health
Osteoporosis
Vitamin D and Magnesium
Vitamin D and Vitamin K
1121 Alcoholics have osteoporosis – Nov 2010 11461
31 Jul, 2013 15:11
admin Liver
Osteoporosis
6694 High dose vitamin reduced pain of fibromyalgia, osteoarthritis, and rheumatoid arthritis - July 2015 10637
05 Dec, 2016 16:03
admin Pain - chronic
Rheumatoid Arthritis
Osteoporosis
Intervention
1092 Suboptimal appreciation by Asian physicians of vitamin D for bone health – Oct 2010 10440
03 Feb, 2013 14:00
admin Osteoporosis
535 Better total hip replacement if have high vitamin D 10237
07 Jul, 2018 12:55
admin Bone - Health
Osteoporosis
Trauma and surgery
4647 Yet again, 800 IU of vitamin D was found to be barely enough to help bones – Lancet Oct 2013 8520
12 Nov, 2015 04:18
admin Osteoporosis
Top news
Falls and Fractures
3122 Calcium and bone disorders in pregnancy – May 2012 8442
19 Aug, 2012 15:18
admin Pregnancy
Osteoporosis
Vitamin D and Calcium
Thyroid and parathyroid
476 Patients like me survey found vitamin D to be number one supplement 7715
27 Jun, 2010 01:38
admin Multiple Sclerosis
Pain - chronic
Osteoporosis
1063 Fewer falls and fractures as vitamin D is increased – 1800 to 4000 IU July 2010 6528
04 Oct, 2017 00:29
admin How much Vitamin D
Osteoporosis
Falls and Fractures
4553 Causes, consequences, and treatment of osteoporosis in men– Aug 2013 6484
11 Sep, 2013 02:45
admin Osteoporosis
2088 CureTogether Vitamin D symptoms, treatments, and causes 6461
25 Dec, 2013 17:03
admin Multiple Sclerosis
Osteoporosis
Evidence for D
Intervention
1000 Review of vitamin D pathways to bone health - July 2010 6322
16 Mar, 2013 23:23
admin Osteoporosis
6703 Calcium supplements proven to NOT reduce fractures, but are proven to INCREASE heart problems – July 2015 6152
24 Jul, 2015 16:51
admin Osteoporosis
Vitamin D and Calcium
Top news
Falls and Fractures
969 Vitamin D for elderly 800 to 2000 IU - Osteoporosis Canada - Sept 2010 6042
23 Jun, 2012 02:17
admin About D - more info.
Osteoporosis
Meta-analysis of Vitamin D
Vitamin D in Canada
3490 Vitamin D Receptor genes bb and BB and Osteoporosis, esp. for blacks – meta-analysis Nov 2012 5582
05 Dec, 2016 16:09
admin Skin - Dark
Osteoporosis
Genetics
Meta-analysis of Vitamin D
Vitamin D Receptor


Here are all of the articles


Osteoporosis is a systemic skeletal disorder characterized by a decrease in bone mass and microarchitectural deterioration of bone tissue. The World Health Organization has defined osteoporosis as a decrease in bone mass (50%) and bony quality (50%). Vitamin D, a steroid hormone, is crucial for skeletal health and in mineral metabolism. Its direct action on osteoblasts and osteoclasts and interaction with nonskeletal tissues help in maintaining a balance between bone turnover and bone growth. Vitamin D affects the activity of osteoblasts, osteoclasts, and osteocytes, suggesting that it affects bone formation, bone resorption, and bone quality. At physiological concentrations, active vitamin D maintains a normal rate of bone resorption and formation through the RANKL/OPG signal. However, active vitamin D at pharmacological concentration inhibits bone resorption at a higher rate than that of bone formation, which influences the bone quality and quantity.

Nutritional vitamin D rather than active vitamin D activates osteoblasts and maintains serum 25(OH)D3 concentration. Despite many unanswered questions, much data support nutritional vitamin D use in osteoporosis patients.
This article emphasizes the role of nutritional vitamin D replacement in different turnover status (high or low bone turnover disorders) of osteoporosis together with either anti-resorptive (Bisphosphonate, Denosumab et.) or anabolic (Teriparatide) agents when osteoporosis persists.

Created by admin. Last Modification: Wednesday October 31, 2018 00:37:59 UTC by admin. (Version 1)

Vitamin D helps treat Osteoporosis – Sept 2018        

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