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Vitamin D and calcidiol are not hormones, but calcitriol is a hormone – Aug 2014

Is vitamin D a hormone or vitamin? ResearchGate Aug 2014


  • Vitamin D itself - neither cholecalciferol (Vitamin D3) nor ergocalciferol (Vitamin D2)
    - is not a hormone, but rather a biomodulator vitamin (capable of gene regulation);
  • the primary active form 1,25-dihydroxyvitamin D (calcitriol) is a calcium-regulating hormone;
  • the primary circulating non-active form 25-hydroxy-VitaminD is a prehormone,
    converted peripherally to the active hormone 1,25-dihydroxyvitamin D (calcitriol).

Vitamin D is the structural raw material that one or more hormones or prehormones (not prohormones) are made from, and meets the strict definition of a vitamin, namely an organic substance present in minute amounts in the natural diet (foodstuffs, not supplements) that is essential to normal metabolism, and insufficient amounts of which in the diet may cause deficiency diseases

From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health
Dr. Norman 2008, full text online

Why "Vitamin D" is not a hormone, and not a synonym for 1,25-dihydroxy-vitamin D, its analogs or deltanoids.

Vieth R. 2004
 Download the PDF from VitaminDWiki.

Click on chart for details

Attached files

ID Name Comment Uploaded Size Downloads
4714 Vit D not a Hormone Vieth.pdf PDF admin 12 Dec, 2014 00:39 54.06 Kb 687
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