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Overlooked Importance of Vitamin D Receptors – Life Extension Mag. Aug 2013

By Logan Bronwell 10 pages including references and pictures


PDF is attached at the bottom of this page

One table from the article
RISK INCREASE WITH LOW VITAMIN D LEVELS*

Autoimmune: Multiple Sclerosis 78 61%
Autoimmune: Psoriasis 79 189%
Autoimmune: Rheumatoid Arthritis 80 24% (Patients taking vitamin D supplements had 24% lower risk.)
Cancer, Bladder 54 83% overall; 494% for invasive tumors
Cancer, Breast 53 150%
Cancer, Thyroid 55 100%
Cognitive Decline 7 41 to 60%
Cardiovascular: (Risk of Heart Attack)12,13,15 38 to 192%
Dementia, Alzheimer's 43 77% increase for lowest vitamin D intake
Dementia, Non-Alzheimer's 7 Almost 20-fold increase
Infection, Respiratory 81 36%
Metabolic: Diabetes 4,82 91% for insulin resistance
38 to 106% for type 2 diabetes
Metabolic: Risk of progression
from normal blood glucose to diabetes 83
77%
Stroke 13,84 22 to 64%

  * Defined either as serum levels less than 30 ng/mL (75 nmol/L),
  or as lowest percentiles vs. highest; risk expressed as percent increased for those with normal or highest levels.


Fairly good overview of vitamin D

>30 ng = sufficiency (standard)
1 billion people have < 30ng (does not mention far more people do not have optimal (50ng) nor high optimal (80 ng))
64% of Americans do not have enough to operate at ‘’peak capacity’’ ( 30 ng)
>50 ng = minimum optimal (lots of discussion on 50 ng being too low, jut right, or too high)
80 ng = high optimal (Unaware that any national standard board recommends this level yet, but I agree)
Shows association of 40+ diseases with low levels of vitamin D

Uses old estimate of how many IU to increase blood level

Uses old rule of thumb: need 100 IU for each additional 1ng of vitamin D
The old estimate is wrong in that the equation is not linear, varies with nanogram level, and varies with body weight
Their example 20 ng ==> 50 ng would equate to 3,000 IU needed
GrassRootsHealth chart indicates 29 IU per lb. For 20 ==> 50 ng
To get to 50 ng a 200 lb person would need to take 5,800 IU

What was not covered in the 6 pages of text

Loading dose can restock vitamin D levels in < 1 month - not have to wait 2-3 months to test again
Groups at high risk of being deficient
   seniors, pregnant women, dark skinned people far from equator, obese, . .
Vitamin D3 much better than Vitamin D2
Random Controlled Trials have proved the benefits of taking Vitamin D3
   most of the references in the article are to associations of vitamin D and a disease
There is a no-cost way to check your self for low vitamin D in the home.
There is a 4X variation between individual response to the same dose
Vitamin D levels are typically very low in the winter/spring (lack of sunshine)
Great reduction in many forms of pain when have optimal or high optimal levels
Vitamin D does discuss Interaction with drugs - watch out for potentially deadly interactions with chemotherapies
There are many forms of vitamin D3 available -liquid, spray, sublingual, vaginal, and even a type for those with digestion problems
There are forms of Vitamin D3 for vegans, Muslems, Jews
If taking > 2,000 IU of vitamin D should also take cofactors - Magnesium being the most important
OK to take vitamin D weekly: daily does not appear to be necessary
Vitamin D can also be obtained from the sun
Genes have a powerful effect on your vitamin D blood levels and the amount of vitamin D which actually gets to your cells
Large variation between vitamin D tests - even on the same machine
About 1 in 300 people trying vitamin D get an adverse reaction - generally because they are deficient in Magnesium

Attached files

ID Name Comment Uploaded Size Downloads
2822 LEF Vitamin D Autg 2013.pdf PDF 2013 admin 21 Jul, 2013 15:58 3.22 Mb 619
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