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Nigerian albinos have vitamin D levels of 96 ng – Oct 2019

Higher vitamin D levels in Nigerian albinos compared with pigmented controls.

Int J Dermatol. 2019 Oct;58(10):1148-1152. doi: 10.1111/ijd.14611

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2 million Albinos in Nigeria (population of Nigeria = 191 million)

  • An investigation into a possible relationship between vitamin D, parathyroid hormone, calcium and magnesium in a normally pigmented and an albino rural black population in the Northern Province of South Africa - 2000 DOI: 10.1002/biof.5520110110

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Enechukwu N1, Cockburn M2, Ogun G3, Ezejiofor OI1, George A4, Ogunbiyi A4.
1 Department of Internal Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
2 Department of Epidemiology, University of Colorado School of Public Health, Aurora, CO, USA.
3 Department of Pathology, University College Hospital, Ibadan, Oyo State, Nigeria.
4 Department of Medicine, University College Hospital, Ibadan, Oyo State, Nigeria.

BACKGROUND:
Several studies have suggested that the lower vitamin D levels in blacks is attributable to the effect of increased pigmentation in blocking cutaneous ultraviolet (UV)-mediated production of vitamin D. Albinos are devoid of melanin and should invariably have higher vitamin D levels when compared with their pigmented counterparts. However, strict photoprotection required in their medical management has been shown to reduce UV-dependent vitamin D production. Associations between low vitamin D and several diseases suggest that the pattern of vitamin D in the black African albino be investigated.

OBJECTIVE:
To compare the vitamin D levels between albinos and normal pigmented controls in Anambra State, Nigeria, and thus highlight the impact of skin pigmentation and sun protection practices on vitamin D levels.

METHODOLOGY:
This was a cross-sectional study of a consecutive series of albinos from the Albino Foundation, Anambra State. The vitamin D levels of 61 albinos and 58 matched pigmented controls were analyzed. The sun exposures of the participants were calculated using validated sun exposure questionnaires.

RESULTS:
The albinos had significantly higher vitamin D levels (median 95.9 [50.1-177.4] ng/ml) than the controls (78.2 [12.1-250] ng/ml). None of the albinos had low vitamin D levels. None of the sun protection practices had significant effects on vitamin D levels.

CONCLUSION:
This study contests the claim that black Africans including albinos have low vitamin D levels. Albinos living in South East Nigeria have significantly higher vitamin D levels than their pigmented counterparts.


Created by admin. Last Modification: Tuesday March 23, 2021 00:14:46 GMT-0000 by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
12899 Albino foundation.jpg admin 02 Nov, 2019 28.92 Kb 1489
12898 Albino.jpg admin 02 Nov, 2019 33.64 Kb 1122
12897 Albino.pdf admin 02 Nov, 2019 192.83 Kb 684