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Increased Quality of Life with increased vitamin D – April 2014

Qual Life Res. 2014 Apr 24. [Epub ahead of print]
Chao YS1, Ekwaru JP, Ohinmaa A, Griener G, Veugelers PJ.
School of Public Health, University of Alberta, 3-50 University Terrace, 8303 - 112 Street, Edmonton, AB, T6G 2T4, Canada.

VitaminDWiki Summary

Vitamin D levels 36 ng average, and as high as 128 ng
We believe that the participants were encouraged to supplement with vitamin D
40 ng increase in vitamin D associated with fewer reported problems

  • Mobility 40% fewer
  • Usual activities 30% fewer
  • Depression and anxiety 30% fewer

See also VitaminDWiki

PURPOSE:
To assess how vitamin D status is associated with health-related quality of life (HRQOL) among older residents of Canada.

DESIGN:
We analysed baseline data of 1,493 Canadians aged 50 years and over in Alberta on HRQOL (EQ-5D-5L) and serum 25-hydroxyvitamin D (25(OH)D) as a measure of vitamin D status. We applied multivariable regression methods to examine the association between vitamin D status and each of the five dimensions and the summary index of the EQ-5D-5L.

RESULTS:
Participants with higher serum 25(OH)D levels were significantly less likely to report problems with mobility, usual activities, and depression and anxiety. Specifically, age- and gender-adjusted odds ratios for reporting problems with mobility, usual activities, and depression and anxiety were 0.58 (95 % confidence interval 0.44-0.78), 0.67 (0.50-0.89), and 0.67 (0.51-0.88) per 100 nmol/L increase in 25(OH)D, respectively. No significant associations were observed for problems with self-care and with pain and discomfort. HRQOL scores combining the responses of each of the five dimensions increased significantly with increasing serum 25(OH)D levels.

CONCLUSIONS:
This is the first study to reveal the importance of vitamin D for the five dimensions of HRQOL in a community-based sample. The observed associations of vitamin D and HRQOL call for intervention studies to strengthen the evidence of the potential benefits of vitamin D supplementation for HRQOL among older adults.



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PMID: 24760533

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3840 QoL T1.jpg admin 25 Apr, 2014 14:51 48.46 Kb 585
3839 QoL.jpg admin 25 Apr, 2014 14:14 45.73 Kb 764
3838 QoL.pdf PDF 2014 admin 25 Apr, 2014 14:11 318.81 Kb 508
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