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Half as much chronic kidney disease infection if supplement with Vitamin D – 2018

Use of vitamin D and infection in patients with chronic kidney disease.

Rev Bras Enferm. 2018;71(suppl 6):2792-2799. doi: 10.1590/0034-7167-2018-0640.
[Article in English, Portuguese]
Silva ECD1, Taminato M1, Fonseca CDD1, Moraes GM1, Longo MCB1, Grothe CE1, Belasco AGS1, Barbosa DA1. ~ha~ dulce.barbosa at unifesp.br

VitaminDWiki

Study amazingly does not state the size of loading nor maintenance doses
Unsure the time period for infection statistics – 0-6 months, 3-6 months? 5-6 months?
Did all chronic kidney patients get maintenance dose?

Kidney category starts with

Kidney category listing has 190 items

see also Overview Kidney and vitamin D
Search VitaminDWiki for dialysis OR haemodialysis 1040 items as of Nov 2018
Search VitaminDWiki for kidney transplant 798 items as of June 2019
"Chronic Kidney Disease" OR CKD 874 items as of Jan 2018

Calcitriol category listing has 45 items along with related searches

Kidney Intervention trials using Vitamin D:


Overview Kidney and vitamin D contains the following summary

  • FACT: Kidney is the primary way to activate vitamin D
  • FACT: When the Kidney has problems, there is less active vitamin D (Calcitriol) for the body
  • FACT: When the Kidney has problems, there is increased death due to many factors - many of which are associated with lack of Calcitriol
  • FACT: There are many on-going intervention clinical trials trying to determine how much of what kind of vitamin D is needed to treat the problem
  • FACT: One Randomized Controlled Trial has proven that Vitamin D treats CKD
  • FACT: Taking extra Vitamin D, in various forms, does not cause health problems - even if poor kidney
  • Suggestion: Increase vitamin D getting into body now - and increase co-factors so that the vitamin D can be better used
      Sun, UV lamp, Vitamin D supplement - probably > 5,000 IU,
    Calcitriol - which bypasses the need for the kidney to activate vitamin D
      Problems with Calcitriol however: typically only lasts for a few hours, also, possible complications
        Update: Pre-cursor of active vitamin D made from plants is better than calcitriol – Sept 2012
  • Category Kidney and Vitamin D contains 190 items

 Download the PDF from VitaminDWiki

Supplement Infection
Vitamin D16 %
No D 32 %

 

Blood levelLoading DoseMaint. Dose
<20 ng/mL 3 months 3 months?
20–19 ng/mL 3 month; 3 months?
>30 ng/mL no maintenance dose
3 month or 6 month?


OBJECTIVE:
To evaluate the effectiveness of vitamin D supplementation as protection factor against infection of patients with chronic kidney disease on conservative treatment.

METHOD:
Retrospective cohort study carried out between 2013 and 2016 in the Conservative Treatment Outpatient Clinics (Ambulatório de Tratamento Conservador) of the Hypertension and Kidney Hospital (Hospital do Rim e Hipertensão) of the Universidade Federal de São Paulo. Data on sociodemographic factors, comorbidity, infection episodes and use or nonuse of vitamin D supplementation for at least 6 months were collected from medical records. The primary outcomes considered in both groups were: presence or absence of infection anywhere on the body (bloodstream, urinary, respiratory and surgical sites).

RESULTS:
A total of 263 patients were included and those who received (n=43) vitamin D had 59% less chance of developing infections (OR=0.41; 95%CI; 0.15-0.99), when compared to those who did not receive.

CONCLUSION: Vitamin D supplementation was a protective factor against infections of all causes.

Created by admin. Last Modification: Friday March 15, 2019 11:16:21 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
11567 Chronic Kidney intervention.pdf PDF 2018 admin 15 Mar, 2019 11:04 531.64 Kb 51
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