Half as much chronic kidney disease infection if supplement with Vitamin D – 2018

Use of vitamin D and infection in patients with chronic kidney disease.

Rev Bras Enferm. 2018;71(suppl 6):2792-2799. doi: 10.1590/0034-7167-2018-0640.
[Article in English, Portuguese]
Silva ECD1, Taminato M1, Fonseca CDD1, Moraes GM1, Longo MCB1, Grothe CE1, Belasco AGS1, Barbosa DA1. ~ha~ dulce.barbosa@unifesp.br

VitaminDWiki

Study amazingly does not state the size of loading nor maintenance doses
Unsure the time period for infection statistics – 0-6 months, 3-6 months? 5-6 months?
Did all chronic kidney patients get maintenance dose?

Kidney category starts with


Overview Kidney and vitamin D contains the following summary

 Download the PDF from VitaminDWiki

Supplement Infection
Vitamin D16 %
No D 32 %

 

Blood levelLoading DoseMaint. Dose
<20 ng/mL 3 months 3 months?
20–19 ng/mL 3 month; 3 months?
>30 ng/mL no maintenance dose
3 month or 6 month?


OBJECTIVE:
To evaluate the effectiveness of vitamin D supplementation as protection factor against infection of patients with chronic kidney disease on conservative treatment.

METHOD:
Retrospective cohort study carried out between 2013 and 2016 in the Conservative Treatment Outpatient Clinics (Ambulatório de Tratamento Conservador) of the Hypertension and Kidney Hospital (Hospital do Rim e Hipertensão) of the Universidade Federal de São Paulo. Data on sociodemographic factors, comorbidity, infection episodes and use or nonuse of vitamin D supplementation for at least 6 months were collected from medical records. The primary outcomes considered in both groups were: presence or absence of infection anywhere on the body (bloodstream, urinary, respiratory and surgical sites).

RESULTS:
A total of 263 patients were included and those who received (n=43) vitamin D had 59% less chance of developing infections (OR=0.41; 95%CI; 0.15-0.99), when compared to those who did not receive.

CONCLUSION: Vitamin D supplementation was a protective factor against infections of all causes.

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