Toggle Health Problems and D

Cystic Fibrosis helped in many ways by Vitamin K – July 2019

Update - RCT to be completed Dec 2021

Vitamin K Supplementation to Reduce Deficiencies in Adults With Cystic Fibrosis (VITK-FK)
Group A: 2mg, every day for 6 months
Group B: 7mg, twice a week for 6 months
Apparently using phylloquinone = K1
Wonder about K2 and D3

Vitamin K and cystic fibrosis: A gordian knot that deserves our attention.

Respir Med. 2019 Jul 6;155:36-42. doi: 10.1016/j.rmed.2019.07.005
Hatziparasides G1, Loukou I2, Moustaki M2, Douros K3.
 Download the PDF from Sci-Hub via VitaminDWiki

Cystic fibrosis (CF) is an inherited genetic disorder with multiorgan involvement. Gastrointestinal tract dysfunction leads to fat and fat-soluble vitamins (A,D,E,K) malabsorption and deficiency of these vitamins. Subclinical vitamin K (VK) deficiency seems to be a common problem in CF patients. However, despite the rest of fat-soluble vitamins being routinely supplemented, this is not a universal clinical practice for VK. Inefficient levels of VK may have significant effects on blood coagulation and bone formation. There are also some data indicating that VK may play a key role on regulation of inflammation. Supplementing CF patients with VK seems rational, but the appropriate dosing regimens are still a matter of debate. This review will try to delineate the problem and communicate the latest opinions on this controversial issue.

Created by admin. Last Modification: Tuesday August 4, 2020 14:33:58 GMT-0000 by admin. (Version 3)
Cystic Fibrosis helped in many ways by Vitamin K – July 2019        
1231 visitors, last modified 04 Aug, 2020,
Printer Friendly Follow this page for updates

Attached files

ID Name Comment Uploaded Size Downloads
12397 Cystic Vitamin K.pdf PDF 2019 admin 29 Jul, 2019 14:48 308.47 Kb 419