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Vitamin D appears to fight Diabetes, MS, RA, Lupus, IBD, Hepatitis, Cancer, Psoriasis, Food allergy, etc – June 2019

Extra-Skeletal Effects of Vitamin D.

Nutrients. 2019 Jun 27;11(7). pii: E1460. doi: 10.3390/nu11071460.
Marino R1, Misra M2.

The vitamin D receptor is expressed in multiple cells of the body (other than osteoblasts), including beta cells and cells involved in immune modulation (such as mononuclear cells, and activated T and B lymphocytes), and most organs in the body including the brain, heart, skin, gonads, prostate, breast, and gut. Consequently, the extra-skeletal impact of vitamin D deficiency has been an active area of research. While epidemiological and case-control studies have often suggested a link between vitamin D deficiency and conditions such as type 1 and type 2 diabetes, connective tissue disorders, inflammatory bowel disorders, chronic hepatitis, food allergies, asthma and respiratory infections, and cancer, interventional studies for the most part have failed to confirm a causative link. This review examines available evidence to date for the extra-skeletal effects of vitamin D deficiency, with a focus on randomized controlled trials and meta-analyses.
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Health Problems
   fought by Vitamin D (left column)

(Number of) studies in topic

Acne (20+ studies)
Attention Deficit Hyperactivity Disorder/ADHD (43+)
Alcohol (29+)
Allergy (24+) Overview
Amyotrophic Lateral Sclerosis/ALS (30+)
Alzheimer's (81+) Overview
Ankylosing Spondylitis (20+)
Antibiotics/Probiotics (81+) Overview
Asthma (129+ ) Overview
Atopic Dermatitis Overview (18+)
Autism (147+) Overview
     Vit. D Receptor (14+)
Autoimmune (188+)
     Systemic Sclerosis (10+)
Back Pain (41+)
     Lumbar Degeneration (14+)
Bipolar Disorder (15+)
Bone - Health (296+)
     Bone Mineral Density (28+)
Breathing (429+)
     Asthma (132+)
     Pneumonia (50+)
Burns/Wounds (30+)
Cancer (259+) Overview
Cardiovascular (476+) Overview
     Atrial Fibrillation (20+)
     Heart Failure (42+)
     HRV (10+)
     Statins (80+)
Carpal Tunnel Syndrome (12+)
Cerebral Palsy (6+)
Cholesterol (51+) Overview
Chronic Fatigue (7) Overview
Cognitive (352+) Overview
     Anesthesia ==> Cog
     Brain (94+)
     Delirium (9+)
     Dementia (50+)
     Mental Stress (10+)
Colds/flu Overview
Concussions (25+)
Chronic obstructive pulmonary disease/COPD (17+)
COVID-19 (1200+)
Cystic Fibrosis (49+)
Dental (97+)
Depression (247+)
     Anxiety ( 11+)
     Omega-3 (29)
Diabetes (521+) Overview
     Diabetic Retinopathy (8)
     Hemodialysis (41+)
     Magnesium (27+)
     Red Meat (4+)
     Metabolic Syndrome + Mg
     Prediabetes (30+)
     Type 1 Diabetes (46+)
     Vitamin D Receptor (23+)
Diseases general (93+)
Ear (17+)
     Otitis Media (10+)
Endometriosis (8+)
Epilepsy(15+)
Falls/Fractures (238+) Overview
Fatigue, Chronic Overview
Fertility/Sperm (128+)
     Erectile Dysfunction (12+)
     IVF (16+)
Fibromyalgia Overview
Fractures Overview
     Ankle (16+)
     Bone & Stress Fractures
     Bone Mineral Density (28+)
     Children (16+)
     Hip Fractures (68+)
Frailty (16+)
Genetics (316+)
     CYP24A1 (31+)
     CYP24R1 (25+)
     CYP27B1 (55+)
     Vit D Binding (170+)
     Vit D Receptor (478+)
       Cancer in VDR (79+)
Gestational Diabetes (34+)
Gout (13+)
Gut (191+) Overview
    Bariatric (13+)
    Clostridium difficile (9+)
     Crohn's (38+)
     IBD (28+)
Hair (20+)
     Alopecia Areata (8+)
Headache (40+)
Health - general (97+)
Hepatitis-B (12+)
Hepatitis-C (13+)
Human Immunodeficiency Virus/HIV (45+) Overview
Hives (10+)
Hypertension (159+) Overview
    Pregnancy (41+)
Hyperparathyroid Overview
Immunity (249+)
Inflammation (160+)
Infection (141+)
Influenza Overview
Kidney (221+) Overview
    Chronic Kidney (63+)
    Dialysis (39+)
Kidney Stones (27+) Overview
Leprosy (16+)
Liver (99+) Overview
Lupus (72+)
Mental Illness (20+)
Mental Stress (5+)
Metabolic Syndrome (97+) Overview
Mortality (292+)
Multiple Sclerosis (386+) Overview
     MS and Herpes (10+)
     MS and Virus (16+)
Muscle (113+)
Muscular Dystrophy (9+)
Myopia (17+)
Obesity (401+)Overview
     Child & Youth (60+)
     Virus and Obesity (25+)
     Weight (67+)
Osteoarthritis (57+) Overview
     Knee (26+)
Osteoporosis (207+) Overview
     BMD (26+)
Pain - chronic (150+) Overview
     Magnesium (13+)
Pancreatitis (10+)
Parkinson's (105+) Overview
Pneumonia (22+)
Pollution (31+)
Pregnancy (849+) Overview
     Breastfed (35+)
     Depression (21+)
     Gestational Diabetes (49+)
     Iodine (21+)
     Magnesium (30+)
     Miscarriage (31+)
     Multiple Sclerosis (13+)
     Omega-3 before and during (49+)
     Preeclampsia (55+)
     Preterm (116+)
     Preterm - Omega-3 (13+)
Prostate - BPH (16+)
Psoriasis (65+)
Respiratory Tract Infection/RTI (8+)
Restless Legs Syndrome (15+)
Rheumatoid Arthritis (111+) Overview
Rickets (126+) Overview
Sarcopenia (28+)
Schizophrenia Overview
Sepsis (38+)
Shingles (15+)
Sickle Cell (17+)   Overview
Skin (108+) Overview
     Aging
     Atopic Dermatitis
     Hives
Sleep (91+)
Smoking (83+)
Spinal Cord (20+)
Spinal Surgery (13+)
Statins (40+)
Stroke (113+) Overview
     Depression (9+)
Suicide (16+)
Thyroid/Parath. (79+) Overview
     PTH (34+)
Trauma/Surgery (323+)
     Bariatric surgery (12+)
     Bone surgery (23+)
     Need Vit D (69+)
     Orthopaedic and Hip surgery (69+)
     Sepsis (36+)
     Traumatic Brain Injury (21+)
Tuberculosis (118+) Overview
Urinary Tract Infection (15+)
Vertigo (18+)
Virus (1220+)
     Air pollution
     Bird Flu
     Child - years after VAX (11+)
     Dengue (13+)
     Epstein-Barr Virus (20+)
     Excess Deaths (23+)
     Hepatitis (29+)
     Herpes or Shingles (13+)
     Ivermectin (35+)
     Long-COVID (72+)
     Magnesium (60+)
     Mononucleosis
     Omega-3 (14+)
     RSV (12+)
     Ultraviolet light (16+)
     Vaccination (198+)
     Vitamin D (650+)
     Vitamin D Receptor (31+)
     Vitamin K
     Zinc (32+)
Vision (92+)
     Cataracts (12+)
     Dry Eye (15+)
     Macular Degneration (14+)
     Myopia (14+)

People and Low Vitamin D

Infant/Child (752+)
     Cancer (13+)
     Cerebral Palsy (15+)
     Fracture, low energy (10+)
     Pneumonia (25+)
     Puberty early if low D (9+)
     RSV (25+)
     Tonsils (9+)
     Vaccination (10+)
     Virus (50+)
Military (27+)
     Veterans (17+)
Seniors (393+) Overview
     Fraility (20+)
     Nursing Homes (19+)
     Sarcopenia (25+)
     Urinary incontinence (15+)
     Vertigo (22+)
Skin - Dark (457+)   Overview
Sports (265+) Overview
     Exercise (68+)
Women (182+) Overview
    Endometriosis (25+)
    Incontinence (16+)
    Menstrual Cycle (6+)
    PCOS
    Premenstrual Syndrome (13+)
    Uterine Fibroid (13+)
    Yeast Infection
Youth (168+)
     Early Puberty (15+)

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  # of studies as of May 14, 2023


Vitamin D appears to fight Diabetes, MS, RA, Lupus, IBD, Hepatitis, Cancer, Psoriasis, Food allergy, etc – June 2019        
1174 visitors, last modified 17 Jul, 2019,
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