From Henry Lahore - administrator of the VitaminDWiki

After reading over 5,000 papers on vitamin D I feel that some topics fall into one of the following categories

Updated Aug 2012

LACK CONSENSUS

• Dark Skin and vitamin D
  • How much vitamin D is needed by people with dark skins?
  • How many generations does it take for a family with dark skin to adapt to high latitudes?
• Vitamin A - consensus that too much is bad, but lack consensus about needing some with vitamin D

UNKNOWN

• Why do 10% of the people who have >60 ng/ml need so little vitamin D to maintain that level?
• Why does it only take < 1 minute of UV to greatly increase the vitamin D in mushrooms and carrots?
• Toxic reaction to vitamin D is very rare - but how often is the "toxic" reaction due to a lack of co-factors?
• Should the vitamin D level remain constant throughout the year?
  • Evolution appears to indicate that the vitamin D level should vary with the season
• UV and vitamin D
  • For some conditions it appears that UV better than vitamin D (e.g. MS)
  • For other conditions it appears that Vitamin D needs UV as well