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Types of Rickets and rickets in Denmark – Feb 2012

Rickets in Denmark.

Dan Med J. 2012 Feb;59(2):B4384.
Beck-Nielsen SS.
Department of Pediatrics, Hospital of Southwest Denmark, Finsensgade 35, 6700 Esbjerg, Denmark. sbeck-nielsen at health.sdu.dk

Rickets is a heterogeneous group of diseases of the growing child caused by defect mineralization of bone. Nutritional rickets is caused by deficiency of vitamin D, calcium or both. Several hereditary forms of rickets exist where the disease proceeds into adulthood. Nutritional rickets was common in the past, but by introduction of preventative administration of cod liver oil and vitamin D supplementation, nutritional rickets became a rarity. During the last decades, case reports of nutritional rickets reappear in the industrialized countries. It is the general conception that in the industrialized countries, hereditary rickets is the most prevalent cause of rickets today. However, the incidence of nutritional rickets and the incidence and prevalence of hereditary rickets in Scandinavia are unknown. The most common form of hereditary rickets is hypophosphatemic rickets (HR). The geno- and phenotype among Scandinavian patients have not been characterized. Especially, the disease in adult patients is not well described. Moreover, there are conflicting reports of the benefits of medical treatment throughout childhood, and in addition on gender differences in disease severity.

PMID: 22293055
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Note: refractory /re·fra·to·ry/ (re-frak´tor-e) = resistant to treatment.

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See also VitaminDWiki

Attached files

ID Name Comment Uploaded Size Downloads
2628 Denmark Rickets types.jpg admin 23 Jun, 2013 13:11 51.53 Kb 7870
2627 Rickets Criteria.jpg admin 23 Jun, 2013 13:10 104.77 Kb 8007
2626 Rickets in Denmark.pdf PDF admin 23 Jun, 2013 13:10 589.57 Kb 949
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