COVID: more than 33 lineages and vaccines – Nov 2022

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36 lineages and 33 vaccines as of Nov 2022

An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants
November 2022 Frontiers in Immunology 13   DOI: 10.3389/fimmu.2022.1034444

 Download the PDF from VitaminDWiki

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BQ.1 = 20% of reported (not actual) cases - CDC - Nov 11, 2022

A variant that produced very mild or no symptoms would not be detected by the CDC

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US Variant lineage as of Oct 13, 2022

Wwitter

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New COVID variant gaining traction in U.S. - Oct 18, 2022 (BQ.1, 10% of cases)

MDEdge

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The Nightmare COVID Variant That Beats Our Immunity Is Finally Here (XBB) - Oct 16, 2022

the Daily Beast

• "... XBB is in many ways the worst form of the virus so far. It’s more contagious than any previous variant or subvariant. It also evades the antibodies from monoclonal therapies, potentially rendering a whole category of drugs ineffective as COVID treatments."
• "The good news is that the new “bivalent” vaccine boosters from Pfizer and Moderna seem to work just fine against XBB, even though the original vaccines are less effective against XBB. They won’t prevent all infections and reinfections, but they should significantly reduce the chance of severe infection potentially leading to hospitalization or death. "

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Is the XBB SARS-CoV-2 Mutant Behind Singapore’s Emerging Surge in COVID-19 Cases? Oct 9, 2022

Trial Site News Oct 9, 2022
XBB (Singapore). BQ.1 Europe

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Rising cases of variants BQ.1 and XBB could make COVID drugs all but useless, study finds - Oct 4. 2022

Salon

• "And then there's XBB, which Cao has described as "the most antibody-evasive strain tested." It combines two different omicron lineages (BJ.1 and BM.1.1.1) to make something so good at evading immunity (either from previous infections or vaccines) that it's close to SARS-CoV-1. It "could cause significant immune escape at a scale never seen before," Cao and his colleagues wrote."

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The biggest COVID concern now is the increased risk of Long-COVID

Long-COVID is now the biggest COVID concern - many studies

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