Pages tagged with "Infant-Child"

884 pages, most important first (overviews, then meta-analyses, then RCTs, then newest). Combine with another topic

• \" Kids and COVID\" - book summary
• Allergy - Overview
• Children need vitamin D - good global overview, poor recommendations for Italian children
• Pneumonia and low vitamin D - many studies
• Cerebral Palsy and Vitamin D - many studies
• Problems after childhood vaccinations - many studies
• Sudden Infant Deaths (SIDS) soon after vaccination - many studies
• Breastfeeding and Vitamin D - many studies
• Diabetes and poor Vitamin D genes - many studies
• Diarrhea and Vitamin D - many studies
• Respiratory viral infection (RSV) and low vitamin D - many studies
• Brain and Vitamin D - many studies
• Tonsillectomy, tonsillitis and Vitamin D - many studies
• Cancer during childhood - many studies
• Transgender associated with autism, low vitamin D, low BMD, etc. - many studies
• Sepsis is both prevented and treated by Vitamin D - many studies
• Respiratory infection, children and Vitamin D - many studies
• Early Puberty if low vitamin D - many studies
• Middle ear infection (Otitis Media) and Vitamin D – many studies
• Juvenile Idiopathic Arthritis is strongly associated with low vitamin D – many studies
• Bladder infection and Vitamin D - many studies
• Children and COVID - many studies
• Far fewer respiratory track infections in infants and children getting 400 IU of Vitamin D – many studies
• Preterm births reduced by Vitamin D - many studies
• Growing pains associated with low Vitamin D - many studies
• Childhood Cancers - Vitamin D can help - many studies
• Low-energy fractures in children with low vitamin D - many studies
• Child Obesity and Vitamin D - many studies
• More vitamin D, more height - many studies
• Prostate and Urinary systems much better with higher vitamin D – many studies
• Tick disorders associated with Vitamin D - several studies
• Down's syndrome and low vitamin D - several studies
• Preemies, Vitamin D, Omega-3, etc. - several studies
• 22% of children (0-5y) are stunted, Vitamin D deficiency is a primary cause – several studies
• Urinary Tract Infection and Vitamin D – several studies
• Kawasaki Disease and Vitamin D - several studies
• Early puberty during pandemic (low vitamin D) - several studies
• Sudden drop of heart rate (vasovagal syncope) is associated with lower vitamin D - several studies
• Recurrent Wheezing in children is associated with low Vitamin D – several studies
• High-dose Vitamin D safe for children (10,000 IU daily, 600,000 IU bolus) – meta-analysis
• Vitamin D cut dental caries in half in 1930's – RCT meta-analysis
• Autism associated with low Vitamin D (again) – Meta-Analysis
• Autism risk is reduced by Vitamin D – early pregnancy or chlldhood – Umbrella review
• Prenatal vitamin D deficiency increases risk of dental cavities by 35% - meta-analysis
• 4,000 IU Vitamin D while pregnant does not decrease infant respiratory problems (no surprise) - meta-analysis
• Food allergy 4 X more likely in 2 year-old children with low Vitamin D – meta-analysis
• Infant respiratory distress reduced by Vitamin D – meta-analysis
• Getting more than 1,000 IU of Vitamin D cut in half childhood risk of influenza, coughs and fevers – Meta-analysis
• Early Childhood Caries 1.4 times more likely if 20-30 ng of Vitamin D – meta-analysis
• High-dose Vitamin D reduced inflammation and insulin resistance (obese children)
• Infections in children reduced a bit by 2,000 IU of vitamin D - meta-analysis
• Childhood BMI decreased when add a little Vitamin D – meta-analysis
• Malaria death 3X less likely in mice given vitamin D (looks good for humans too) – meta-analysis
• ADHD in children 2.6 X more likely if low vitamin D – meta-analysis
• ADHD risk factors include low Zinc, Vitamin D, Magnesium and Omega-3 (umbrella review)
• Vitamin D during pregnancy increased child’s bone mineral density – meta-analysis
• IBD treated in children by Vitamin D, especially if use more than 2,000 IU daily for 12 weeks – meta-analysis
• Childhood and youth obesity – more than 4,000 IU vitamin D average daily would help – meta-analysis
• Small doses of Vitamin D do not reduce childhood breathing allergies – meta-analysis
• Many ear problems are strongly associated with low vitamin D – meta-analysis
• Need at least 6,000 IU daily while breastfeeding to eliminate Vitamin D deficiency – meta-analysis
• NAFLD associated with low vitamin D (in children too) – meta-analysis
• Urinary Tract Infection in children 4.8 X more likely if low Vitamin D – meta-analysis
• Childhood asthma about 1.3 times more likely if poor Vitamin D Receptor – meta-analysis
• Metabolic syndrome risk in children decreased 12 percent for each 10 ng increase in Vitamin D – meta-analysis
• Jaundice associated with 7 ng less vitamin D – Meta-analysis
• Less obese child if supplemented with Vitamin D as an infant– meta-analysis
• T1 Diabetes 3X lower risk if high vitamin D (over 40 ng) – Meta-analysis
• Acute Lower Respiratory Infections in Children - associated with low vitamin D – meta-analysis
• Vitamin D loading doses of up to 400,000 IU OK for adolescents – meta-analysis
• Septic children have low Vitamin D (54 studies, ignored Vitamin D Receptor) – meta-analysis
• Infants need 400 IU of vitamin D to prevent rickets – meta-analysis
• Metabolic Syndrome in children is associated with low vitamin D – review
• Juvenile Rheumatoid Arthritis associated with low vitamin D, but how low – meta-analysis
• Type 1 Diabetes (T1DM) 1.6 X more likely if low vitamin D – meta-analysis
• Critically ill children with low vitamin D: 2.5 X more likely to die or stay 2 days longer - meta-analysis
• Low Vitamin D results in adverse pregnancy and birth outcomes – Wagner meta-analysis
• Omega-3 helps childhood cognition – meta-analysis
• Vitamin D loading dose was as effective as daily dosing (rickets in this case) – RCT
• Poor protein binding gene associated with poor Vitamin D response – RCT
• Omega-3 reduced violence in children and violence between parents – RCT
• Infants getting an additional 800 IU of vitamin D for 2 years had 60% fewer psychiatric symptoms at age 7 – RCT
• Long-COVID in children (PASC) treated by daily 2,000 IU of Vitamin D - RCT preprint
• 6,400 IU of Vitamin D is safe and effective during breastfeeding – RCT Dec, 2020
• Breastfeeding mother getting 6400 IU of Vitamin D is similar to infant getting 400 IU – RCT
• Upper canine teeth extracted faster if take Calcitriol (a form of Vitamin D) - RCT
• 400 IU of Vitamin D daily provided no benefit (UK RCT this time)
• Bronchiolitis hospital stay cut by 2 days with 200,000 IU vitamin D – if deficient – RCT
• Atopic dermatitis reduced by at least half if take 2800 IU Vitamin D while pregnant - RCT
• 1600 IU vitamin D safe for infants – RCT
• Supplement preterm infants with vitamin D if less than 80 ng – RCT
• 4.4 X INCREASE in other respiratory infections in children with influenza vaccinations – RCT
• 430 genes changed when 3,800 IU Vitamin D added in late second trimester – RCT
• Give ICU children a bolus dose of 10,000 IU of vitamin D per kg – RCT underway
• Children had a better response to Vitamin D given every 2 weeks than daily – RCT
• Omega supplementation helped preemie sensory processing – RCT
• Bedwetting reduced 40 percent by 1,000 IU of vitamin D for 2 months – RCT
• 2X less risk of respiratory distress syndrome if 50,000 IU of Vitamin D just before premature birth – RCT
• Response to infant 2,000 IU Vitamin D daily was in 194 ng, monthly dosing was 20% less – RCT
• Monthly 120,000 IU of Vitamin D while breastfeeding was good – RCT
• Atopic Dermatitis not helped by small weekly doses of Vitamin D (8K 2y-6y.16K 12y-18y) – RCT
• 2800 IU of Vitamin D in late pregnancy resulted in 3X fewer fractures, 4X fewer enamel defects in offspring – RCT
• Half of infants had less than 20 ng of Vitamin D with 800 IU (need more) – RCT
• Obese asthmatic children Vitamin D - 50,000 IU then 8,000 IU daily - RCT
• Bone fractures of children not reduced if given little vitamin D, no Calcium etc. – RCT
• Autistic symptoms reduced by Vitamin D and or Omega-3 – RCT
• Infant infection reduced by half with vitamin D supplementation – RCT
• Respiratory Tract Infection visits 2.5 less likely with vitamin D: Pregnancy 2000 IU, Infant 800 IU – RCT
• 3X less Septic Shock in children with sepsis getting 150,000 IU of Vitamin D - RCT
• NAFLD in children nicely treated by combination of Vitamin D and Omega-3 – RCT
• Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT
• Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT
• Little second-hand smoke problem in children if mother had added Vitamin D while pregnant - RCT
• Attention Deficit Hyperactivity Disorder impulsivity reduced by daily 1,000 IU of vitamin D – RCT
• ADHD significantly treated by daily Magnesium plus weekly Vitamin D – RCT
• Autism problems reduced by Vitamin D, Omega-3 – RCT
• COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT
• Dark-skinned infants got minimal vitamin D from 4 minutes sunbathing daily – RCT
• Grip strength of children not improved by 800 IU Vitamin D daily (not nearly enough) – RCT
• Candida infections in PICU reduced by Vitamin D in yogurt – RCT
• Prebiotics increased Vitamin D in celiac disease patients (gut-friendly Vit. D also helps) – RCT
• Faster growth in infants getting 1200 IU of Vitamin D – RCT
• Breastfed Infants need more than an daily average of 800 IU of Vitamin D – RCT
• Children need 2000 IU of Vitamin D (India) - RCT
• Vitamin D for infants – 100,000 IU monthly is better than 400 IU daily – RCT
• Additional Vitamin D not help – infants previously had 35 ng of vitamin D – RCT
• Severe Non-Alcoholic fatty liver disease treated by Omega-3 – RCT
• Infants getting 800 IU more vitamin D daily got no neuro benefit (virtually all Fins were sufficient) – RCT
• 400 IU of Vitamin D helped breastfed infants, need more – RCT
• NAFLD somewhat treated in children with 2,000 IU Vitamin D daily – RCT
• Mother got 100,000 IU of vitamin D monthly, breastfeeding infant got a little – RCT
• Breastfed infant bones not helped by 800 IU of Vitamin D (not enough) – RCT
• Infant Respiratory Infections not reduced by mothers taking small amount of vitamin D (28,000 weekly)– RCT
• 400 IU of Vitamin D provided no benefit to children (not a surprise) – RCT
• Fewer pre-infants were vitamin D deficient when they got 800 IU – RCT
• Recurrence of child pneumonia delayed by 100000 IU of vitamin D – RCT
• Half the risk of Influenza -A in infants taking 1200 IU of vitamin D for 4 months – RCT
• Takes a year to restore children and youths to good levels of vitamin D without loading dose - RCT
• Toddlers with more than 48 ng of vitamin D weighted less and were thinner – RCT
• Children in Mongolia helped by 800 IU of Vitamin D (need a lot more) – RCT
• Vitamin D needed to get children to just 20 ng in winter 800 IU white skin, 1100 IU dark (Sweden) – RCT
• Newborn Vitamin D - single 50,000 IU is better than daily – RCT
• 2X improved development by severely malnourished children with 2 loading doses of vitamin D – RCT
• Child soccer players who were deficient were helped by a single 200,000 IU vitamin D dose – RCT
• Vitamin D levels in children optimized with six Vitamin D biscuits – RCT
• Little weight loss in obese children from very small amount of vitamin D (1200 IU) – RCT
• Bones of white children not helped by 1,000 IU of vitamin D (Northern latitudes) – RCT
• Vitamin D and Omega-3 may treat Type 1 Diabetes – RCT 2024
• 50,000 IU Vitamin D one time after birth helped – RCT
• Extreme preterm infants helped somewhat by 800 IU of vitamin D – RCT
• Half as many tooth enamel defects in child if 2400 IU Vitamin D in late pregnancy – RCT
• Preemie immunity (Treg) vastly improved by 800 IU of Vitamin D daily – RCT
• Infants receiving 1600 IU of vitamin D were safe and healthy – RCT
• Third study found that Infants needed 1600 IU of vitamin D – JAMA RCT
• Allergic rhinitis in children reduced somewhat during pollen season by just 1,000 IU of vitamin D – RCT
• Treatment of neonate sepsis greatly aided by Vitamin D – RCT
• Risk of infant Asthma cut in half if mother supplemented Vitamin D to get more than 30 ng – RCT
• Asthma in 3 year olds decreased somewhat with 4,000 IU during pregnancy – RCT
• All preteen aged girls in India taking 2,000 IU of vitamin D got levels above 20 ng – RCT
• 2000 IU vitamin D during pregnancy and 800 IU to infant resulted in less use of antibiotics – RCT
• Black infant recurrent wheezing rate dropped from 42 percent to 31 percent with just 400 IU of vitamin D – RCT
• Vitamin D loading dose of 300,000 IU for children – 3 weeks with capsules, biscuits, injection – RCT
• 1200 IU vs 400 IU of vitamin D did not improve bone health or immunity of children who were sufficient – RCT
• Adding Vitamin D, Omega-3, etc to children’s milk improved memory (yet again) – RCT
• Infants getting up to 1600 IU did not increase blood level of vitamin D – RCT
• Extreme preterm infants need a total of 1,000 IU of vitamin D daily – RCT
• 800 IU of vitamin D got most white Danish children to 20 nanograms – RCT
• Children helped by 2,000 IU of vitamin D, but not RDA amount (600 IU) – RCT
• Preemies need 1,000 IU of vitamin D – RCT
• 2000 IU of vitamin D should improve toddlers health in winter – RCT almost completed
• Infants getting 1 g of Omega-3 for 12 weeks got better brains – RCT
• Severely burned children recovered muscle capability much faster with daily 1000 IU of vitamin D – RCT
• Vitamin D improved child muscle mass even without varying dose with weight – RCT
• Five times less mite allergy when vitamin D added in mid pregnancy and to infant – RCT
• 800 IU vitamin D for infant and 2000 IU for mother is good, not great – RCT
• Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT
• 1000 IU vitamin D not enough in winter to restore levels in children - RCT
• Many preemies need at least 800 IU of vitamin D – RCT
• Infants getting 1400 IU vitamin D weekly grew better – RCT
• Maternal vitamin D: slight differences between daily vs single doses – RCT
• 400 IU of vitamin D for infants is good, 200 IU is not enough – RCT
• Sepsis is fought by Vitamin D in 9 ways
• 2,000 IU of vitamin D reduced schizophrenia chance by 77 percent (male infants) - 2004
• Children's autoimmune diseases (T1D, thyroid, celiac, JIA) linked to low vitamin D and cofactors - review
• Vitamin D levels have been crashing since 1995 (Polish Children, Elite Military, etc)
• 400 IU of Vitamin D daily got only half of the infants to 30 ng/mL (might need 1,600 IU)
• 81% of the baby foods in one US city were ultra-processed
• Type 1 Diabetes risk increased if high postpartum Vitamin D binding protein
• Vitamin D is more bio-available when children are critically ill (less Binding Protein)
• Ear infections in children 3X more likely if poor vitamin D binding protein
• Vitamin D (40-70 ng) in Children’s Health – review
• Pediatric sleep apnea associated with low vitamin D – many countries, Egypt 2026
• Shaken Baby Syndrome - probably caused by Ehlers-Danlos Syndrome
• Critically ill children – randomized clinical trial to give single doses of up to 400,000 IU of vitamin D – 2019
• Early brain development helped by Iron, Iodine, Vitamin D, Omega-3, Zinc etc.
• Severe asthma children 31X more likely to develop chronic obstructive lung disease
• Ticks in children twice as likely to be severe if lower vitamin D
• Tick disorder reduced by Vitamin D supplementation
• Chronic tick disorder 2X less likely if 11 ng higher level of vitamin D
• Vitamin D during lactation – 6,000 IU mom or 400 IU infant (Hollis, Wagner chapter)
• Childhood asthma problems eliminated for months by 600,000 IU of Vitamin D injection
• 600,000 IU of vitamin D2 every 4 months for decades in East Germany – 1987
• Stressors as a fetus or child can cause health problems in adult (perhaps via epigenetics)
• UK Day-Cares being offered grants to develop vitamin D methods
• Death of infant twins due to 5 vaccinations, not measles
• 4X reduction in childhood Primary Nocturnal Enuresis by Vitamin D
• Daytime Sleepiness in children 1.7X more likely if low vitamin D
• Air pollution: half of all US children
• Brittle bone disease (Osteogenesis Imperfecta) is probably helped by Vitamin D
• The 6 percent of infants hospitalized for ARI are 2.2 X more likely to be Vitamin D deficient
• Allergic rhinitis sublingual therapy was 22X more successful if those who got a good level of Vitamin D
• Children of Pacific Islands: 96% have insufficient Vitamin D
• Vitamin D Webinar - cost of preterm birth etc- Baggerly
• Unvaccinated Children Are Far Healthier - 12 studies agreed
• Vaccinated kids: 4X more asthma, 6.5 X more neuro, more chronic
• Infant Vitamin D: 1000 IU weekly is better than 240 IU daily (better compliance)
• Toxins, not viruses, are the cause of Diarrhea in babies - Hypothesis
• Surgery for Pediatric Fracures 55 X more likely if < 12 ng of Vitamin D
• Low Calcium (Hypocalcemia) in infants: the principal cause is low Vitamin D
• ADHD and Vitamin D Deficiency
• Infants born early or low vitamin D are more likely to get sepsis
• Breastfed infants have low levels of Iron, Vitamin B-12, and Vitamin D (Turkey)
• Big increases in Vitamin D supplementation in NZ, especially the very young and very old
• Childhood Infections reduced 1.3X to 3X by exclusive breastfeeding
• Finland reduced infants Vitamin D from 4,000 IU to 400 IU (1964-1990)
• Pediatric fractures heal much faster when Vitamin D levels are > 30 ng
• Blaming some child deaths on covid shots, FDA vows stricter vaccine rules - Nov 2025
• Vaccinations resulted in increased office visits for children 16 months later
• 37 VAERS Events after COVID-19 vaccination in pregnancy
• 25X higher risk of low Vitamin D (S. Asian children in London)
• Respiratory problem 1.9 X more likely if age 2-4 and low Vitamin D
• Very Low Birth Weight Preemies are in hospital 9 days longer if Vitamin D was delayed
• ICU child deaths reduced when add just 95 IU of Vitamin D
• Smoking while Pregnant increases atopic dermatitis if not add Vitamin D
• Infant bone density not improve if increase only Vitamin D (no surprise)
• Autism may be synergistically treated by Vitamin D and probiotics
• Comparison of Vitamin D supplementation guidelines for children – China 400 IU 2012
• Short stature (stunting): might be low Vitamin D or K, Iron, Zinc, etc
• 2.7 X increase in % of African-American children who were Vitamin D deficient
• Not All That Glitters Is Gold: Questioning High-Dose Vitamin D Supplementation in Young Children
• The top 10 chronic childhood health problems are all associated with low Vitamin D
• 400 IU of vitamin D does not help infants much (no surprise)
• Preemies should have vitamin D supplements – reaching an agreement
• Dental caries cut in half by vitamin D, review of 24 old clinical trials
• More dental caries in children who have less than 30 ng of Vitamin D – Review
• Increased risk of Childhood COVID: 4.9X if low Vitamin D, 3X if poor receptor
• Obesity is associated with 1 to 5 poor vitamin D genes (childhood obesity in this case)
• CT scans appear to increase risk of Cancer: 5% in adults, 40% in infants
• Childhood vaccinations are recommended, not mandatory - Japan since 1994
• Asthma is worse in overweight children
• Obese children have poor vitamin D genes (CYP27A1, CYP2R1, CYP27B1)
• Children with Long-COVID 2.2 X more likely to have with low vitamin D
• Vitamin D injection did not help critically ill children (injection take too long to help)
• Multiple Childhood Vaccinations increased autism risk by 4.4 X (Florida)
• Children who had COVID had 2.2 X higher risk of long COVID if had less than 30 ng of Vitamin D
• Pink eye (seasonal allergic conjunctivitis) associated with low vitamin D and high vitamin E
• Cancer patients have low vitamin D (Pediatric in this case)
• Rett syndrome associated with low vitamin D, treated by Omega-3
• Increased risk of child obesity if low vitamin D while pregnant
• Gene that predicts wheezing is associated with low vitamin D
• Infant-Child
• Children with low vitamin D became adults having 2X more chronic health problems
• French children prescribed liquid vitamin D - daily, monthly and quarterly
• 3X reduction in respiratory infections in children taking more than 800 IU of Vitamin D weekly
• T1 Diabetes treated by Vitamin D and Omega-3
• Perhaps getting Vitamin D as infant decreases risk of Autoimmune Diseases as adult
• Growing pains reduced in 91% of children with a single dose of Vitamin D
• Risk of childhood pneumonia reduced 30% by high Vitamin D
• Bronchopulmonary dysplasia, in a third of preemies, 87% reduced risk for just 1 ng higher Vitamin D level
• Childhood Fractures – consensus report on vitamin D
• Children with fracture history have lower vitamin D levels
• Leg fractures in children requiring surgery healed months faster if high vitamin D
• Hospital costs for an extreme preemie adds 58,000 dollars to the cost of full term birth
• Dr. Sears podcast with Carole Baggerly about Vitamin D (with transcript)
• Preterm birth rate increased 60 percent in 50 years (US)
• Vitamin D and Omega-3 benefits to pregnancy and infants
• Children in Intensive Care need Vitamin D loading dose of 10000 IU per kg (nearing a consensus)
• Highly likely that neonate will be vitamin D deficient if the mother was
• Pfizer COVID vaccinations resulted in altering immune systems (increased IgG4 )
• Very preterm infants with low vitamin D are 4 X more likely to have retinal problems
• Monthly vitamin D dosing better for children than daily (again)
• Urinary Tract Infection in infants 5.6 X MORE likely if low Vitamin D, 3.3 X LESS likely if supplement
• Preemie Respiratory Distress Syndrome is 5X more likely if low vitamin D
• Omega-3 added to father’s diet reduced offspring’s obesity (mice)
• Low Vitamin D in infants - video interview of Dr. Holick
• Bedwetting more frequent if Vitamin D levels less than 14 ng
• Bedwetting 3X more likely with low vitamin D
• Only 3.4% of Portuguese children get vitamin D supplements (a good dose taken weekly costs only 10 cents)
• Atopic Dermatitus more likely if e-cigarette, passive smoke while pregnant or Caesarean
• FDA study of 4 million children found 2 COVID-19 vaccination red flags, but continue to push boosters
• Fathers taking antibiotics at time of conception had 3X higher infant deaths (mice – so far)
• 2400 IU Vitamin D daily to get 90% of children above 30 ng, etc. – Cashman
• Childhood Dental Caries about 2X more likely if Vitamin D is less than 20 ng – review
• Children in hospital: those with COVID had lower Vitamin D, Iron, etc.
• Vitamin D deficiency in children: 9%, but up to 75% in children with fractures
• Vitamin D half life is shorter in asthmatic children who are more obese
• Obese children had less gene methylation (gene not work as well)
• US has the most vaccinations before age 1 and the most deaths
• Increase infant Vitamin D: forification, daily, weekly, monthly, breast milk - Review
• Hay fever and autism 2X more likely if poor Vitamin D Receptor (children in India)
• Children eating a plant-based diet should add Vitamin B12, Vitamin D, etc
• Children with Kawasaki disease are 29 X more likely to be Vitamin D deficient
• 18,000 schoolchildren in Canada to be suspended for not being vaccinated
• Wheezing and asthmatic children have weaker Vitamin D responses
• Asthma by age 7 if wheezing before preschools and poor vitamin D Receptor
• Vitamin D levels are low during Recurrent Wheezing
• Childhood cancers – give Vitamin D loading dose if low
• Arctic school children in Russia: only 1 in 11 has more than 30 ng of Vitamin D
• Newly diagnosed Children with Cancer have low vitamin D, especially if black
• Vitamin D levels in new borns are so low that they are considering supplementing to prevent Rickets (Japan)
• Poor children were 2X more-likely to be vitamin D deficient (Ireland)
• 24 Vitamin D global guidelines for children, huge diversity
• 94 percent of children with Chronic Neurological Diseases had low vitamin D
• Depressed infants have very low Vitamin D (7.5 ng)
• Vitamin D recommended for infants by 98% of Belgian pediatricians - 2024
• Nutrient consumption – only 7% of recommended DRV of Vitamin D (German Children in this case)
• COVID Vaccinated Children 1.25 X More Likely to Be Hospitalized for Respiratory Illness - CDC
• COVID kids were more likely to have a poor VDR (4.3 X), than low Vitamin D (2.6 X)
• France has injected 200,000 infants with RSV vaccine, based on no long-term data - Here we go again
• Prevention of allergies, eczema, asthma, in children – Vitamin D during pregnancy is a principal solution
• UVB added in classroom reduced cavities, increased height, increased academics. etc
• Asthma in child 2.3 X more likely if both parents asthmatic (unless add Vitamin D) – VDAART
• Monthly vitamin D dosing during lactation was great for infant and mother
• Caries in deciduous teeth about 2X more likely if low vitamin D – Review
• FDA drug to TREAT child Type 2 diabetes (based on 1 trial of only 50)
• Brazil mandates COVID-19 vaccine for children
• A common recurrent childhood fever (PFAPA) was reduced by half by 2000 IU of daily vitamin D
• Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks
• Preemies with pneumonia infection have especially low vitamin D levels (12 ng)
• 16,000 Physicians and Scientists Agree Kids Shouldn’t Get COVID Vaccine
• Infants getting lots of vaccinations are 2X more likely to die
• Doctors in NY cannot opt out of COVID boosters for children
• Children 41X more likely to be vitamin D deficient if both parents were deficient
• Anemia 8X more likely in infants if low vitamin D
• Vitamin D levels of breastfeeding mothers and infants in 3 cities
• Breast-feeding mothers need 2000 IU of vitamin D to get infants to even 12 ng
• Effects of low vitamin D on pregnancy and neonate – review
• Respiratory infections in children 6 X more likely if low Vitamin D (avg of 2 studies)
• Concern about accidentally giving infant too much liquid vitamin D
• COVID, Long-COVID and Vitamin D in children - Review
• Thin Choroid (eye lining) in children thickened by 300,000 IU of Vitamin D
• Children getting 60,000 IU monthly got to vitamin D level of 33 ng
• Cost-effective to give Vitamin D to all children to prevent acute respiratory infection
• Childhood Cancer Survivors have worse arteries due to anticancer therapy
• 3% fewer respiratory problems in children if single 100K vitamin D in 3rd trimester
• Both parents smoke – child’s vitamin D level was 30 percent lower and worse asthma
• Pediatric trials of high dose vitamin D -163 are in a single online database
• ADHD, Autism, Early Psychosis and Omega-3 – review
• ADHD children eat less fatty fish (Omega-3 again)
• Autism and ADHD type disorders were 14X more likely in survey of extreme preterm vaccinated infants
• Autistic children have lower levels of Iron, Vitamin D, Magnesium, etc
• Autistic children were 3.6 X more likely to have low levels of vitamin D
• Vaccinated children had more chronic diseases
• Omega-3 probably can decrease Autism and ADHD
• Autism 2X to 3X more likely if poor Vitamin D Receptor
• Autism increased 53 percent between 2017 and 2020
• Infant should have fewer problems with air pollution if high maternal vitamin D
• Croup (due to viruses) has surged with Omicron
• Multisystem Inflammatory Syndrome of COVID in Children 3X more likely if low Vitamin D
• Recommend 100 IU of vitamin D per kg of infant - Poland
• Higher Vitamin D-binding protein is good (neonates in this case)
• Forearm fractures in children having low Vitamin D had 3.8 X higher risk of surgery
• The Vitamin Deficiency Signs That Can Send You to Prison
• All children with Chronic Kidney Disease had low Vitamin D (Pakistan hospital)
• Child abuse fractures – 96 percent were associated with poor bones (low vitamin D, etc.)
• Low energy bone fractures associated with low vitamin D
• 6X increase in excess deaths of children since vaccinations were started
• Vitamin D spray results in bigger response than drops
• COVID 5.5 X more likely to be severe if low Vitamin D (children in this case)
• Behavior disorders reduced with Magnesium, Omega-3, and Zinc
• Cancer in children (Leukemia) more likely to recur if 20-30 ng of vitamin D
• Phototherapy to reduce infant Jaundice decreases Vitamin D, Mg, etc.
• Jaundice and vitamin D
• Milk Consumption Is strongly linked to Type 1 Diabetes – Dr. Greger
• T1 Diabetes reduction by high Omega-3 and Vitamin D – GRH ongoing observation
• Tripledemic: Flu, COVID, and RSV (all fought by Vitamin D)
• PICU layoffs due to pandemic lulls, but children are now getting 3 years of viral infection all at once
• CDC advised to recommended annual COVID vaccination of all children over 6 months old
• RSV kills 100,000 children annually around the world (Vitamin D can help)
• Birth Defects – March of Dimes Global Report (does not even mention Vitamin D)
• March of Dimes pays for study of Vitamin D
• FDA approved 5-11 vaccine booster (based tiny unpublished study without asking advisory panel)
• Vitamin D Deficiency in children in SE Asia
• 2.5 X more health compaints in children and youths if low vitamin D
• T1 Diabetes in child not prevented by a tiny amount of vitamin D during pregnancy
• Opioids leading cause of poisoning deaths in young children
• US children not getting enough vitamin D, recommends free milks and perhaps 3X increased fortification
• Vitamin D before, during, and after pregnancy
• Vitamin D associated with reduced COVID-19 risks in children - Grassroots
• Recent increases in pediatric endocrine problems may be decreased by Vitamin D
• Obese during childhood usually results in obese adult (M.R., not a surprise)
• Hepatitis normally rare in children: huge increase after lockdown (Adenovirus, low Vitamin D)
• Poor prognosis of solid childhood cancers 14.7 X more likely with a poor Vitamin D Receptor
• Growing pains reduced 57 percent by vitamin D therapy
• Pandemic Vitamin D levels dropped by 3.3 ng (perhaps less D, more health problems)
• Children have less severe COVID, but just as much long-haul as adults
• Kawasaki disease (strawberry tongue) not treated by occasional 400 IU of Vitamin D
• Kawasaki disease (strawberry tongue) associated with very low vitamin D
• Increase in children with low vitamin D and with tibia fractures during COVID
• 28,859 deaths and 238,412 serious injuries due to vaccines, how many more when add ages 0.5 - 5
• Pregnant while black increases chance of death – mothers 3X, infants 2X (low Vitamin D)
• Vitamin D reduces childhood allergic airway diseases (confirmed by metabolomics this time)
• Puberty Starts Earlier Than It Used To (unaware of Vitamin D)
• Arab preterm infants often have less than 10 ng of vitamin D - 2010
• Remdesivir approved to treat COVID in Infants, yet Vitamin D is 3000 X more cost effective and widely used
• More UV during first trimester, less Osteoporosis in offspring
• Vitamin D congress on pregnancy and childhood diseases
• Overweight children associated with low vitamin D during pregnancy – 2015, 2018
• Infant risk of obesity increased by 50 percent if low vitamin D during pregnancy
• Moderate to high Myopia 2X more likely if low Vitamin D (China)
• Vitamin D helps some child health problems in Pakistan
• Risk factors for severe COVID in children are all related to low vitamin D (same as adults)
• Liver transplants in children more likely to be rejected if insufficient vitamin D
• Children with higher Vitamin D had less severe COVID (no surprise)
• Dosing error gave 12000 IU daily vitamin D to infant, but no indication of any problem
• Turkey gave 400 IU vitamin D to all infants and reduced Rickets by 60X - 2011
• Giving vitamin D to ALL children reduced (rickets) symptoms by 60 percent
• French pediatric consensus: 30 – 60 ng of Vitamin D
• Majority of South Asian children and youths have low vitamin D (85 pcnt of neonates)
• Vitamin D Toxicity with no long term problems starts at 300 ng (infant with 222 ng had no symptoms)
• COVID children with multisystem inflammatory syndrome have less than 10 ng of vitamin D
• Vitamin D might reduce Multisystem Inflammatory Syndrome in children
• Hospitalized children with COVID-19 and inflammation had lower vitamin D
• 8 of 10 pediatric COVID-19 infections were Vitamin D deficient (49 patients)
• Younger are much less likely to die of COVID than elderly (posters)
• IBD in children might be associated with low sun exposure
• Acute lower respiratory infection 5X more frequent with low vitamin D intake
• 3X fewer infant dental caries if good level of vitamin D while pregnant
• Infants have gotten free 400 IU of vitamin D in Turkey since 2005, More for longer would be even better
• Many sleep problems are associated with low Vitamin D (children in this case)
• Children with cancer were deficient in Vitamin D, Vitamin C, and Zinc
• Vitamin D levels very low for some childhood cancers, then got lower
• Cancer of the eye in children: most of the risk factors are associated with low vitamin D
• Vitamin D2 not help – again ( T1 diabetes– which has been helped by D3)
• Severe infant caries 10X higher risk if low vitamin D (under 14 ng)
• Vitamin D levels dropped 42 percent immediately after pediatric cardiac surgery
• Lower IQ among Autistic Black children (5 in 10) than White (3 in 10)
• Half of Mongolian schoolchildren have less than 10 ng of vitamin D
• COVID Vaccination trial for kids: 11 red flags
• Congenital heart surgery dropped vitamin D levels by 40 percent
• Obese children with celiac disease had lower levels of vitamin D
• Children with Celiac Disease were 2.6X more-likely to be vitamin D deficient
• Obese children had 2.2 X less response to a single dose of Vitamin D
• Decreased response to vitamin D in white children having poor Vitamin D binding gene
• TB vaccinations increased vitamin D levels a year later
• 93 percent of US children had less than 40 ng of vitamin D a decade ago
• Reasons for children having low vitamin D (proposed by 10 societies)
• 73 percent of US infants still do not even get 400 IU of Vitamin D
• Recurrent RTI treatment success: Conventional 71 pcnt, Vitamin D 96 pcnt
• A poor infographic of Vitamin D for children
• Children no longer get much vitamin D from milk - fortify at home
• 36X more likely for an infant to be low vitamin D if exclusively breastfed (Hong Kong)
• Severe childhood COVID-19 associated with Vitamin D deficiency (hospital in Turkey)
• Breastfed infants: 90 percent had less than 20 ng of vitamin D, formula-fed: 15 percent
• Severe childhood dental problems 2.4 X more likely if breastfed for more than two years (low vitamin D)
• Allergy medications may be improved by Vitamin D (6X for birch pollen in this case)
• Fewer drugs needed after cardiac surgery if higher levels of vitamin D (Chinese children)
• Hospital has banned Dr. Holick due to testifying in cases of infants with broken bones- August, 2021
• Severe pediatric COVID 5.5 more likely if low vitamin D (review of 6 studies)
• Lack of vitamin D in infants can result in broken bones and shaken baby syndrome
• Danish study of childhood diseases vs vitamin D fortification
• 1.8 X more heart medicines needed by children after heart surgery if low Vitamin D
• Taking vitamin D for health problems has raised D levels a bit (child Arthritis this case)
• Arthritic children have low vitamin D (84 percent of the studies)
• Vitamin D required for breastfed infants – daily or monthly, infant or mother
• Breast milk rarely now has even 20 percent of needed vitamin D – even in sunny climates
• Breastfeeding a child without adding vitamin D increases risk of many food allergies (egg whites in this case)
• 42X increased vitamin D testing of children, no increase in levels (too little vitamin D prescribed to make a difference)
• Children's Cancer hospital now testing vitamin D frequently and supplementing weekly
• UK people and doctors still clueless about vitamin D – Survey
• 10 Reasons why children no longer have healthy levels of Vitamin D
• Child 49 percent higher risk of being overweight if preeclampsia during pregnancy
• Asthmatic children 5X more likely to have a poor Vitamin D Receptor
• Virtually all infants in Poland got 400 IU of Vitamin D daily (not enough, non-daily is better)
• Infant 7.6 X more likely to be Vitamin D deficient if mother had been
• Infants need more sun than 17 minutes per week on 6 percent of skin
• Anemia in children 3.5 X more likely if low vitamin D
• Consensus recommends at least 20 ng of Vitamin D for childhood cancer (not nearly enough)
• Vitamin D insufficiency in child 15X more likely if father is Vitamin D insufficient
• Vitamin D in US children: those having more than 40 ng increased 60 percent (2001-2010)
• 26 X increase in Vitamin D prescriptions for youths in England in 8 years
• Very low Vitamin D levels after Liver transplant in children (need Calcitriol or topical)
• Childhood Cancer survivors – only 1 in 25 had consumed Vitamin D RDA
• Rare infant vitamin D toxicity – due to errors which resulted in more that 240,000 IU
• Preemies with low Vitamin D are 14 percent more like to have expensive gut problems (necrotizing enterocolitis)
• Preemies with poor lungs (Respiratory distress syndrome) have low levels of vitamin D
• Increased weight in children 8X more likely for each unit increase in adenovirus (if ignore Vitamin D)
• Mental health of children: vast majority of studies reviewed found that vitamin D helped
• Pneumonia in Egyptian Children 3.6 X more likely if poor Vitamin D Receptor
• Low vitamin D associated with 5.5X increased risk of low bone mineral density
• Acute pneumonia in children 3X less likely if greater than 30 ng of vitamin D
• Somewhat less Type 1 Diabetes in Wales recently – perhaps more sun or more vitamin D
• Children with low vitamin D far more likely to hospitalized with COVID-19
• 87 percent of children with COVID–19 had low vitamin D (small study)
• Poor hip joint in infants associated with poor Vitamin D receptor
• Vitamin D toxicity is extremely rare, accidental, and very mild in Iranian children
• Children with low Vitamin D slept 1 hour less, had 1 hour later bedtimes
• 75 percent of unexplained sudden infant deaths had inadequate level of vitamin D
• Type 1 Diabetes (Autoimmune) and Vitamin D, Vitamin D Receptor and Cathelicidin
• 13 possible reasons why COVID-19 is less severe in children
• FDA doubles the amount of vitamin D permitted in milk
• 2,000 IU vitamin D recommended for pediatric rheumatology
• Germany raised Vitamin D RDA to 800 IU - helped infants, but not children (who need even more)
• Preemies still have low vitamin D at age 6
• Allergic Rhinitis in infants treated by 1,000 IU vitamin D daily
• Obesity 3X more likely in US children having low vitamin D
• Lower Respiratory Tract Infection in Infants reduced 5.9 X by daily 600 IU of vitamin D (China)
• Vitamin D deficiency in pediatric critical illness: Time to move on from observational studies
• 83 percent of children had less than 20 ng of vitamin D – 15 ng avg for hispanic
• Child movement disorders reduced in 1 week by Vitamin D injection (China)
• Sleep half hour longer if OK level of Vitamin D (2-year olds)
• Low birth weight far more likely if African-American (low vitamin D) – 1997,
• Low birth weight 3X more likely if mother had less than 25 nanograms of vitamin D
• Polish children need 45 minutes of noon sun to get 800 IU of Vitamin D
• Infant and child immunity depends on Vitamin D and two Vitamin D genes – Review
• Group is giving only 200 IU of Vitamin D to 70 million women and children to prevent Rickets
• Respiratory infection in infant was 7 X more likely if low cord Vitamin D
• Largest cause of infant deaths is respiratory infections, which is associated with low vitamin D
• Vitamin D improves a child’s immune system – can now be claimed in Europe
• PICU children with low vitamin D levels have worse health scores (PRISM-III)
• Vitamin D DRI for children lowered to 200 IU in Korea
• Micronutrients (such as Vitamin D) for critically ill children – review
• Childhood allergies (Atopy) 4.8 X more likely if low vitamin D in early pregnancy
• Type I diabetes in dark skin children associated with low vitamin D if far from equator
• Childhood Food Allergies (UK 1 in 14) – huge recent increase (low vitamin D)
• Infant Vitamin D doubles 6 months after birth (can double in 2 weeks)
• Antibiotics increased the risk of asthma by 47%, and allergies by 25%
• Crohn's disease in black children is worse in 6 ways
• Hospitalization consumes vitamin D in children
• Eating fish improves cognition (Omega-3 fish during pregnancy in this case)
• Seafood (Omega-3) during pregnancy increased childhood IQ by 8 points – review
• Turkey needs to give Vitamin D to children too (infants get D for free)
• Romania joins Turkey in giving free Vitamin D to all infants – 2018
• Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies
• Juvenile Rheumatoid Arthritis 8 X more likely if poor Vitamin D receptor
• Sudden kidney infection in children was 9X more likely if poor Vitamin D receptor
• Children in India – 1 in 7 extremely low Vitamin D, 1 in 10 prediabetic
• Type I Diabetes stopped increasing in Finland after Vitamin D levels were raised
• Child exposed to smoke is 1.5 X more likely to have low vitamin D
• European Food Safety Authority (EFSA) found “paucity” of Vitamin D data for infants
• Poor motor development in infant was 40 percent more likely if low maternal vitamin D
• I have a PhD in immunology and this is how I keep my daughter from getting sick during the winter
• Type II Diabetes in children in India increased 4 X in 20 years
• Vitamin D consensus for Italian children, 30 ng needed, up to 4,000 IU if over age 10
• Obese children and youths need more vitamin D – Review
• Prisoners Get More Time Outdoors Than Children
• Child is 2 X more likely to get influenza if have older sibling (perhaps closely-spaced birth)
• Relapses of Acute Lymphoblastic Leukemia (ALL) – 1 in 5 are due to genes mutated by chemotherapy
• Premature infants (30 weeks) who got 800-1000 IU of vitamin D were much healthier
• Type 1 diabetes trial having problems getting participants – too many taking Vitamin D or Omega-3
• Children with Cancer were 3X more likely to be vitamin D deficient
• 100,000 IU Vitamin D weekly for 4 weeks is safe and effective for children
• No preemie had even 30 ng of vitamin D, lower D associated with more Respiratory Distress
• Teeth from 19th century London indicate that most children were Vitamin D Deficient
• Juvenile idiopathic arthritis 2.2 X more likely if poor Vitamin D Receptor
• More UVB at 12th week of pregnancy associated with less Juvenile Idiopathic Arthritis
• Vitamin D deficiency was mistaken for child abuse in a small fraction of 2800 cases
• Lupus in children 2.6 X more likely if they had poor Vitamin D Receptor
• Medicaid pays medical bills of 40 percent of children and 46 percent of pregnancies
• Vitamin D deficiency and childhood obesity: interactions, implications, and recommendations (5,000 IU)
• The more vitamin D the lower the infant BMI
• Newborn vitamin D level is often lower than maternal, this study says it is double
• Rickets in 30 percent of infants in India who had low vitamin D
• 93% of newborns of military in Hawaii had low vitamin D
• Teeth enamel problems (MIH) 11 percent less likely with just 4 ng more vitamin D
• Food allergy is linked to season of birth, sun exposure, and vitamin D deficiency
• 6 year-old children were 5X less likely to have food allergies if supplementing with vitamin D
• Growing pains associated with low vitamin D
• 3X more allergy to peanuts if child born with low UV
• Food allergies 6 times higher in South Australia - 2009
• Ability to walk at age 1 is 3.9 X more likely if sufficient vitamin D
• Malnourished children with low vitamin D were 2.8 X more likely to be stunted
• Bronchiolitis in children associated with both pollution and low solar
• Bronchiolitis had 1.3 X longer hospitalization if low Vitamin D (1016 infants)
• Type 1 Diabetes prevention with Vitamin D and Omega-3 – Symposium
• Overweight children are 3.4 X more likely to have low Vitamin D
• Children with allergies often depressed and anxious (low micro-nutrients, such as vitamin D, were not mentioned)
• Hypertension 2X more likely as a youth if low vitamin D for first 3 years of life
• Infant sepsis strongly associated with low vitamin D
• Sepsis in infants 4.8 X more likely if poor vitamin D receptor
• Food allergies in children may be due to earlier low Vitamin D, Omega-3 and Zinc
• Food allergies are associated with Vitamin D thru genes, etc.
• 11X more non-immigrant children allergic to peanuts if vitamin D less than 20 ng
• Childhood Asthma somewhat reduced by 2400 IU vitamin D late in pregnancy (néed more, earlier)
• Babies 3.6X more likely to go to hospital for asthma if asthmatic mother had low vitamin D while pregnant
• Children short sleep 12 percent more likely for each 1 ng lower vitamin D at birth
• Children with periodic fevers (PFAPA) have half the vitamin D levels of others
• Vitamin D in European baby formula to be reduced 17 percent
• Hay fever (allergic rhinitis) risk reduced 20 percent for each 100 IU of vitamin D during early pregnancy
• Infant Problem-Solving Skills Linked to Mother’s DHA Omega-3 Level During Pregnancy
• 400 IU of Vitamin D in food provided virtually no benefit to children
• Bone marrow foot oedema (rare pain in children, all were Vitamin D deficient)
• Spinal muscular atrophy (rare disease) might be helped with vitamin D
• Growing pains reduced 60 percent by monthly Vitamin D
• All myopic children had less than 50 ng of vitamin D
• Vitamin D compliance 3X higher when children with fractures actually knew their low vitamin D level
• Polish pediatric center: 40 percent took vitamin D
• Half as many teeth problems if higher cord blood level of vitamin D
• Growth Hormone treatment raised vitamin D levels by 16 ng – 2018
• Growth Hormone Deficiency treated by treating Vitamin D Deficiency
• T1 diabetes in children helped with two doses of 150,000 IU of vitamin D and Calcium
• Cerebral palsy language development significantly helped by vitamin D
• Respiratory Distress Syndrome in preemies 5 X more likely if poor vitamin D receptor
• Major increases in childhood health problems
• 34 percent increase in hospital admissions for low vitamin D in a single year (UK)
• Less child bone if mother lacked vitamin D
• Oxidative stress and inflammation associated with low vitamin D in children – review
• Vitamin D deficiency is associated with prediabetes in obese Swedish children
• Large increase in dark skin children with vitamin D deficiency in Glasgow
• Black infants had far lower vitamin D levels which did not vary with season
• Infants 2X more likely to get schizophrenia if had very low vitamin D
• Which children need Vitamin D tests (no consensus, should give Vit D to all)
• Extreme Heat Events increase congenital heart defects (perhaps low vitamin D)
• Young white children helped by 1500 IU of vitamin D
• Preterm babies have low vitamin D, but recover in 6 weeks with 800 IU supplementation
• Premature infants need 400 to 800 IU of vitamin D
• CYP24A1 gene mutation is a cause of rare infant vitamin D toxicity
• Congenital Heart problems - vitamin D levels drop even lower after surgery, loading dose probably required - thesis 2015
• T1 Diabetes – how it may be prevented and treated by Vitamin D
• Infants sometimes lack Oxygen – 1,000 IU Vitamin D daily helps
• Less sun (less vitamin D) more anaphylaxis (severe allergic reaction)
• Infant allergy to cow’s milk will go away if have high levels of vitamin D
• Hand, Foot, and Mouth disease (virus) strongly associated with low vitamin D
• Severe hand, foot, and mouth virus is 2.9 X more likely if poor Vitamin D receptor
• Child died in hospital, death due to low vitamin D, mother is suing hospital
• Infants who have iron deficiency anemia are 4X more likely to be vitamin D deficient
• Anemia 1.9X more likely in white children having lowish vitamin D
• Vitamin D deficiency 2.5 X more likely in iron-deficient children
• Breastfed infants 6 times more likely to deficient in Vitamin D and Iron
• Type 1 Diabetes is increasing – decreased vitamin D is one of the many possible reasons
• Children with Idiopathic arthritis have very low Boron levels
• Immature lungs in immature newborns – Vitamin D helps
• Type 1 diabetes 3.5X more frequent if low vitamin D - Medscape CME
• Vitamin D - Effects on Human Reproduction, Pregnancy, and Fetal Well-being
• Children entering ICU with low vitamin D were 3.5 X more likely to have a poor ICU score
• Cochrane review of Vitamin D and stunting will be ignoring 9 important concerns
• More US infants die in 1st day than in all other developed countries COMBINED (and US gives vaccine in first day)
• Pneumonia is increasing (now 1 in 6 child deaths), more vitamin D studies needed
• Inflammatory Bowel Disease in children is associated with low Vitamin D, Iron (also low Zinc for Crohn’s)
• No tooth decay in children with adequate Vitamin D (small study)
• Type 1 diabetes 1.6 times more likely if a Vitamin D Receptor problem
• Infant Vitamin D – JAMA said 1600 IU, Europe says 1,000 IU upper limit
• Early Type 1 Diabetes May Shorten Women’s Lives by 18 Years
• 6400 IU vitamin D is effective during breastfeeding
• 96 percent of ear, nose, throat children had less than 30 ng of vitamin D
• 40 percent of internationally adopted children had low vitamin D (10-20 ng)
• Only 1 in 6 infants got even 400 IU of vitamin D daily
• Infection in first six months of life: White 69 percent, Black, 78 percent
• Childhood pneumonia not treated by 100,000 IU of vitamin D – Cochrane (need more, inhaled)
• Unclear if septic shock in children is fought by Vitamin D
• Low levels of Vitamin D in UAE juveniles (virtually none had 30 ng)
• 400 IU of vitamin D for the mother gave only 1 in 340 infants sufficient vitamin D
• Systematic review of effective Vitamin D interventions in children - perhaps 2019
• Small for gestational age with low vitamin D – 3.6X higher for blacks than whites
• Vitamin D supplementation by only 1 in 60 US Children – JAMA
• Child Asthma increased 2.1 X by antibiotics, Child milk allergy increased 4.4 X by PPI
• Childhood Respiratory Health hardly improved with 600 IU of vitamin D (need much more)
• Less than half of health providers recommend 600 to 1000 IU of vitamin D (age 1-18)
• Poor handgrip strength in 5-year-old girls 3X more likely if low vitamin D
• Vitamin D needed by pregnant women and neonates (in developing countries now too - 2 tables)
• Very low birth weight infants were OK with 600 IU of vitamin D plus Calcium and Phosphorus
• Preemies have increased need for vitamin D and Calcium (Rickets)
• Indoor pollution is a problem with obese black asthmatic children
• UK infants are the least likely to get Vitamin D in Europe – political action overdue
• Vitamin D deficiency in childhood - old lessons and current challenges
• Vitamin K guidelines for neonates need to be reconsidered
• Saudi infants – 4 in 10 have low Vitamin D, 8 in 10 have low Calcium (hypocalcemia)
• Forearm fractures in children having low Vitamin D had 1.7X higher risk of surgery
• Vitamin D in European children – no consensus on “adequate” levels
• 60 percent of preemies have brain damage from lack of brain Oxygen, which is associated with low vitamin D
• Hens fed a form of vitamin D had more hatchable eggs and more immune chicks
• T1 Diabetes associated with many other autoimmune diseases (all related to low vitamin D)
• RSV (bronchitis and viral pneumonia) in infants associated with low vitamin D and antibiotics
• Breastfed Infants in Iowa got very little vitamin D, especially if winter or dark skin
• Russian children need 2,000-4,000 IU of Vitamin D to get most above 40 ng
• Children with forearm fractures have lower levels of vitamin D
• Rapid newborn breathing (transient tachypnea) associated with low vitamin D
• Mother and father on trial for infant death – set free – death was due to rickets
• Omega-3 in infancy reduces Obesity following antibiotic (confirmed in rats, suspected in humans)
• MS relapse rate for children was 34% less for every extra 10 ng/ml of vit D
• Born too soon – premature births report by W.H.O. – 2010
• Early tooth decay 1.9 X more likely if a poor Vitamin D receptor
• Vitamin D levels in moms and infants are low and sometimes very low
• Type 1 Diabetes 14 percent more likely with 2 Vitamin D Receptor mutations
• Infant sunbathing 30 minutes a week raises vitamin D levels to only 20 ng in 6 months
• Nepalese infants who sunbathe, etc. have much higher levels of vitamin D than their mothers
• Sunlight for babies – US Govt 1933
• Supplement omega-3 based on weight
• Less bad gut bacteria in infant if even tiny amount of vitamin D during pregnancy
• Obese moms who breastfeed (without Vitamin D) had low bone density in infants
• The Convergence of Two Epidemics: Vitamin D Deficiency in Obese School-aged Children
• Give 400 IU to all infants – majority of Turkish pediatricians
• Childhood cancer survivors have increased chronic health problems as adults
• Took 4 months of 400 IU vitamin D for Iranian infants to get serum level of 30 ng
• Large soft spot on infant’s head (anterior fontanelle) is associated with low vitamin D
• 1900 IU provides some increase in Vitamin D in both mother and breast milk
• When to start Vitamin D after European births - UK 180 days, many 6-31 days, the rest 1-5 days
• Canadian Paediatric Society – vitamin D recommendations unchanged since 2007
• Black infants far less likely to be breast-fed (wonder – culture or low Vitamin D)
• 10X increase in cost of vitamin D per child-year in UK in 6 years
• Hypothesis – Australia has highest rate of food allergy due to avoiding the sun
• Omega-3 in breast milk increases with increased Omega-3 intake (review of 22 studies)
• Infant Shudders, Shivers, Jitteriness etc can be early signs of low Vitamin D
• Children with limited mobility are at high risk of being vitamin D deficient
• Long-Term bedridden patients have poor vitamin D and poor bones
• Low vitamin D in Pediatric ICU – 5 times more ill (morbidity) – Spanish
• Infant-Child Vitamin D recommendations from NZ (many are wrong)
• Infant muscle development best with 400 IU of vitamin D (not 800)
• Season of birth (Vitamin D) vs birth weight, puberty, body size, etc.
• Viral Pneumonia in children 52 X more-likely if very low vitamin D (trend)
• Vitamin D guidelines of American Academy of Pediatrics said none should be even tested, yet 91 percent had less than 30 ng
• Children stayed in ICU 3.5 days longer if low vitamin D
• Symptoms of vitamin D deficiency vary with the age of the child
• Low Vitamin D during pregnancy or as infant causes health problems decades later
• Rotavirus diarrhea (nearly every child gets it) is strongly associated with low vitamin D
• Quick restoration of vitamin D in children – 10,000 IU per kg loading dose was not enough
• Infant hospitalized after Vitamin D overdose (8,000 X too much)
• At birth, lower levels of vitamin D associated with higher levels of inflammation
• Many US kids have less than 40 ng of Vitamin D – 99 out of 100 blacks, 91 out of 100 whites
• Infants have low levels of vitamin D – associations with phototherapy and miscarriage
• Diarrhea more common in children having low vitamin D
• Childhood allergy, asthma and eczema associated with repeated low vitamin D tests
• Type 1 diabetes risk not decreased if add 400 IU vitamin D while pregnant (no surprise)
• Vitamin D does not help children (if only use 400 IU of D3 or D2 or quarterly) – Cochrane
• Neonate loading dose of 30,000 IU vitamin D helped a lot
• Low bone mineral density of male children is associated with low BMD of parents
• Only 1 in 5 toddlers get recommended minimum vitamin D
• Less able to understand language at age 2 if low vitamin D during second trimester
• Twice as many neonates got vitamin D after instructions to doctors were simplified.
• Multiple sclerosis in children – low vitamin D is a potential factor
• Hypothesis – Multiple Sclerosis risk increases with low UV, viral infections, and antibiotics in childhood
• Severe tooth decay in children unless supplemented with Vitamin D drops
• Food allergies and low vitamin D – thymus may be the connection
• More childhood allergies when vitamin D is less than 15 ng
• Still unsure of association between vitamin D and asthma and allergies – review
• Youths with autoimmunity disorders were 2.3 X more likely to be vitamin D deficient
• Food allergy 12X more likely if low vitamin D and vitamin D binding gene problem
• Respiratory tract infections in childhood – vitamin D is needed, no consensus of how much
• Prevention of vitamin D deficiency in mothers and infants worldwide - a paradigm shift.
• Higher vitamin D at birth associated with less diabetes and obesity 35 years later
• Diabetes (Type 1) increasing 4 percent per year, now 30,000 in the UK
• Type I diabetes 2X more likely if mother had low vitamin D
• Benefits of Omega-3 on brain development
• High vitamin D levels in Romanian children – wonder why
• Small for gestational age and insulin at age 6
• Increasing amount of omega-3 in mother’s milk resulted in fewer infant allergies
• Breastfed child needs even more vitamin D supplementation after 1 year
• Breastfeeding exclusively may not be best strategy for bone health (if not add vitamin D)
• Obese children – 71 percent had low vitamin D
• Births with low vitamin D weighted less (Hispanic too)
• Language understanding by infant is associated with vitamin D level during pregnancy
• All infants with small heads (less than 33 cm) were from mothers with low vitamin D levels
• T1 Diabetes 35 percent more likely if 10 degrees further from equator (less vitamin D)
• T1 Diabetes associated with low vitamin D
• Dental Caries risk in children cut in half if more than 20 nanogram of Vitamin D
• Vitamin D and pregnancy – review
• Inflammation (CRP) 3X higher in Winter-Spring neonates with low vitamin D
• 3X increase in UK children who are vitamin D deficient in just 5 years
• Every child with kidney problems (ideopathic nephrotic syndrome) had low vitamin D
• Chronic kidney with low vitamin D: 90 percent of pediatric nephrologists now recommend more D
• Infant in ICU much more likely to die if low vitamin D
• Breastfed infants may get enough vitamin D (provided mom gets 6400 IU)
• Vitamin D levels of Mexican children: mean 38 ng
• Omega-3 and infant development - dissertation
• Infant positional skull deformation 7X more frequent if less than 400 IU of vitamin D
• Leading cause of death age 0-5 – vitamin D deficiency
• Children low on vitamin D were 2X more likely to have diarrhea and vomiting
• Too much vitamin D: 1 pcnt increase in infants with food allergy, too little: 500 pcnt increase in children with food allergy
• High level of maternal vitamin D and infant food allergy – controversy
• Infant psychomotor development has a U shaped relationship with vitamin D cord blood levels
• Respiratory distress after preterm birth is more likely if low vitamin D – review
• All preemies with Chronic Lung Disease had low vitamin D levels
• Infant vitamin D repleated with 200 IU ( if you consider 12 ng to be repletion)
• Neonate horses (as well as neonate humans) having low vitamin D are more likely to die.
• Only 1 in 10 UK parents had been told about vitamin D by their child’s doctor
• Only 1 in 4 UK children had EVER gotten vitamin D supplements
• Most European infants get vitamin D supplements, vs only 1 in 50 in US
• Low dose Vitamin D during pregnancy and infancy results in strange acute respiratory infection response
• Newborn acute lower respiratory tract infection associated with low maternal vitamin D
• High intracranial pressure in children – most common cause was low vitamin D
• Low vitamin D during pregnancy associated with four health problems in children
• Low D in developing countries – less than 5 ng in some children in China
• Newborns in sunny Jordan have very low Vitamin D (histogram)
• WHO says that infants not need vitamin D until 6 months and only 200 IU after - 2013
• Vitamin D levels in Europe
• Children born of mothers with low vitamin D at 18 weeks had 4 health problems
• Bone fracture in children 1.8 X more likely if born in winter (low vitamin D)
• UK program to increase Vitamin D (Healthy Start) continues to be a farce
• 3X more kids were vitamin D deficient when entering UK hospitals than 4 years before
• Post-mortem analysis of children in London Hospital – only 1 child had adequate level of vitamin D
• Dark skinned children were vitamin D deficient in Italy (not infants)
• Delayed scholastic achievement associated with low vitamin D levels
• Heavier Babies Do Better in School (perhaps more vitamin D)
• Child Bone health – (incorrect) recommendations by US Pediatric and Bone Health groups
• Several papers on Vitamin D for critically ill children in Journal of Pediatrics
• Extremely low vitamin D in mother: early birth and low weight in children, mortality in mice
• 400 IU vitamin D for breastfed - American Association of Pediatrics
• Unsupplemented infants were 19X more likely to be vitamin D deficient
• 16% of exclusively breastfed infants so low on vitamin D that they had rickets
• Breastfed without vitamin D supplements – a problem for NZ infants
• Even after informing mothers of the importance of vitamin D supplementation few did so
• Preterm infants, kidney, rickets and vitamin D intake: is it time for rewriting the history
• 5 out of 6 children who died in pediatric critical care unit had low vitamin D
• Death of Babies in UK due to vitamin D deficiency
• Your vitamin D deficient infant could be taken away from you – Council
• Preemies have low vitamin D levels yet only get 400 IU
• Infants do not tolerate some brands of Vitamin D – additives, color, etc
• Preschool children with low vitamin D visited their doctor more often
• Diabetic children often need more than 7,000 IU of vitamin D
• Asthma is not treated by weekly 14,000 IU of vitamin D (proven yet again)
• Vitamin D Deficiency is a Strong Predictor (4X) of Asthma in Children
• Hypothesis: recent increases in flat-headed infants is due to low vitamin D
• 300 IU is not enough vitamin D for preterm infants
• Family Medicine vitamin D survey: 400 IU for infants, but many prefer supplementing mom
• Presentation: pre and post natal vitamin D, with audience comments – Manchester UK
• Hip problem in boys (PERTHES' DISEASE) associated with low vitamin D
• 2000 IU vitamin D3 was not enough for children with chronic kidney disease
• More Hypertension in obese children with low vitamin D, especially at night
• Very poor follow-thu with vitamin D testing and supplementation of obese children
• Mothers and infants in India have very low levels of vitamin D
• 90 percent of Indian mothers and infants had less than 20 ng of vitamin D
• Children have better Calcium levels when vitamin D levels are higher than 30 ng
• Low vitamin D in International Adoptees (somewhat typical)
• Obese children gain weight more quickly when have low vitamin D
• Maternal supplementation (vitamin D is an emerging topic) Lancet
• FOODLets or Sprinkles might increase vitamin D in children
• 100,000 IU of vitamin D every 90 days was not frequent enough to prevent Diarrhea
• Study found little proof that preemies need more vitamin D
• Vitamin D deficiency for children’s bones is 14ng, based on PTH analysis
• Review of Micronutrients such as vitamin D for women and childhood
• RXRA gene activity at birth weakly associated with bone density at age 4
• Some preemies needed more than 400 IU of vitamin D
• Childhood mental disorders vs levels of vitamin D
• 5X increase in vitamin D deficiency after leaving primary school (Tasmania)
• Vitamins D and A, before and after birth
• Infants in France and Finland need 1000 IU of vitamin D, but apparently infants in US need only 400 - 2013
• Infants again said to need more than 400 IU of vitamin D
• Child bone conference: many vitamin D and ricket abstracts
• 400 IU vitamin D was insufficient for 6 percent born of Vitamin D-Deficient Mothers
• Only about 10 percent of breastfed infants get even the minimum recommended vitamin D
• Vitamin D3 far better than D2 at raising infant vitamin D blood levels
• 400 IU not enough to raise preemies vitamin D level to 30 ng – Dissertation 2010
• Fewer than 15 percent of 5 year-olds getting vitamin D prescriptions in France
• Many infant infections avoided with supplementation with 400 IU of vitamin D
• Half of children with chronic illness had low levels of vitamin D
• UK Milk producer sets vitamin D day, yet UK milk rarely has vitamin D
• Obese mothers with adequate vitamin D gave birth to low D and fat infants
• 6000 IU may be needed to get vitamin D in breast milk – systematic review
• Dark Skinned babies probably need vitamin D to prevent nutritional rickets - 2001
• Nutritional Rickets in Denmark especially among immigrant children
• Reminder – 400 IU is enough only when infant already had a good level of vitamin D
• Osteopenia in preterm infants
• French Society of Paediatics Vitamin D recommendations
• Chief UK Medical Officer recommends only 280 IU for children
• UK pediatricians have a lot to learn about vitamin D
• Obama task force told that childhood Obesity linked to Vitamin D Deficiency
• Vitamin D Genes associated with Childhood Asthma And Lung Function
• Cardiovascular risk factors in children associated with low vitamin D
• Children with severe caries were 2X more likely to have inadequate vitamin D
• Infants born early had low vitamin D levels
• Breastfed infants in Germany with 250 IU of vitamin D got to 56ng
• Vitamin D prior to and after birth
• 830 IU vitamin D (50000 bi-monthly) helped infants
• Infants getting 500 IU achieved 60 ng vitamin D in blood
• Most mothers still do not supplement infants with vitamin D
• 400 IU vitamin D daily got most infants above 20 ng
• More Calcium absorbed from formula than breast milk, lacking vitamin D
• Bone health markers generally not improved by 550 IU of vitamin D after birth
• Vitamin D for children – translated from Spanish
• 400 IU vitamin D for infants and 2000 IU during pregnancy if high risk
• FDA warns against over 400 IU vitamin D for infants, especially with droppers
• Very short children were very low on vitamin D and Calcium
• Infants in Montreal at risk of rickets – telephone survey
• Vitamin D in the Infant: Requirements for Safety 2006
• Infants given 400 800 and 1200 IU of vit D all had increased blood levels
• All babies in Ireland should have 200 IU of vitamin D
• 200 IU vitamin D daily not enough to change infant mortality
• Bone density of children did not improve with 3 month of vitamin D
• Hypercalcemia in 3 children who had more than 30 ng of vitamin D
• Children need Vitamin D etc if on a gluten-free diet just like other kids
• Majority of infant seizures in India due to lack of vitamin D
• Babies Receive Heart Transplants Instead of Vitamin D Treatment
• Intervention of 400 IU of vitamin D raised infant blood levels 14 ng
• Like their diabetic mothers, infants had low vitamin D and were slightly diabetic