Pages tagged with "Cardiovascular"

519 pages, most important first (overviews, then meta-analyses, then RCTs, then newest). Combine with another topic

• Overview Cardiovascular and vitamin D
• Overview Metabolic Syndrome and vitamin D
• Cardiology diseases highly associated with low vitamin D
• Vitamin D is important for cardiovascular health
• Repeat heart attacks cut in half when vitamin D was dosed to reach > 40 ng - RCT
• Heart Failure and Vitamin D - many studies
• Heart Failure and Vitamin D meta-analyses - many studies
• Statins and Vitamin D - many studies
• Cardiovascular health and Vitamin D - review of 127 studies
• Vitamin K, cardiovascular health, and stroke - many studies
• Coronary Artery Disease and Vitamin D - many studies
• Cardiovascular Disease is treated by Vitamin D - many studies
• Arteries and Atherosclerosis and Vitamin D - many studies
• Atrial Fibrillation decreased by Vitamin D or Magnesium - many studies
• Virus and Cardiovascular problems - many studies
• Cardiovascular problems reduced by Omega-3 - many studies
• Low heart rate variability (bad) is associated with low Vitamin D and COVID – many studies
• Peripheral Arterial Disease (PAD) and Vitamin D - several studies
• Kawasaki Disease and Vitamin D - several studies
• Endothelium (lining of blood vessels, heart) and Vitamin D - several studies
• Sudden drop of heart rate (vasovagal syncope) is associated with lower vitamin D - several studies
• C-reactive protein (heart disease marker) reduced by vitamin D – meta-analysis 2014, 2019
• T2 Diabetes and associated CVD problems fought by Vitamin D (weekly 50,000 IU)
• Peripheral arterial disease risk is 1.5X higher if low vitamin D – meta-analysis
• Chronic Heart Failure helped by Vitamin D – meta-analysis
• Vitamin D reduces many Cardiovascular risk factors (provided doses are personalized) – meta-analysis
• Little Vitamin D does not reduce risk of CVD – RCT meta-analysis
• COVID Vaccinations increased risk of cardiac deaths in youths by 19%
• Myocarditis, Pericarditis 2X more likely if had COVID vaccination in previous 30 days - meta-analysis
• Afib 40% less likely after heart by-pass if have enough Vitamin D – meta-analysis
• Risk of heart failure increased 1.4X if low vitamin D – meta-analysis
• Risk of Cardiac failure reduced 20 percent by 800 IU of vitamin D and Calcium – meta-analysis
• Atrial fibrillation sometimes treated by Omega-3 – meta-analysis
• USPSTF says no evidence that Vitamins prevent CVD or Cancer (data disagrees)
• CAD patients with low vitamin D were 1.6 X more likely to die – 27th meta-analysis
• Cardiovascular death 1.5X more likely if less than 20 ng of Vitamin D – 22nd meta-analysis
• Arterial Stiffness and Vitamins – only Vitamin D was found to help – meta-analysis
• Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis
• Recurrrent Cardiovascular deaths cut in half if 10 ng more Vitamin D – meta-analysis
• Daily aspirin reduced chance of heart problems by 0.4 percent (but 50X more reduction if Vitamin D) – Meta-analysis
• Atrial Fibrillation 1.3 times more likely if low vitamin D – meta-analysis
• Statin pain reduces Vitamin D levels by 4 ng ( 9 studies) - Meta-analysis
• COVID-19 deaths 4 to 7 X more likely if Diabetic, Hypertensive, or CVD - meta-analysis
• Cardiovascular disease associated with postmenopausal non-human primates – meta-analysis
• Coronary Artery Disease without diabetes 5 times more likely if VDR gene problems – meta-analysis
• Vitamin K (across all dose sizes and types) decrease Vascular Stiffness – meta-analysis
• Blood vessels not helped by small vitamin D doses – meta-analysis
• Omega-3 reduces heart problems by ~5 percent – meta-analysis by Heart Association
• Cardiovascular deaths 12 percent less likely if have 10 ng more vitamin D – meta-analysis
• Low-dose vitamin D does not help cardiovascular (many were 100-1,000 IU) – meta-analysis
• Vitamin D supplementation reduces many Cardiovascular Disease markers– meta-analysis
• Small or infrequent doses of vitamin D do not reduce heart failure much – meta-analysis
• Peripheral Arterial Disease patients have low vitamin D levels – meta-analysis
• Omega-3 Cardiovascular meta-analysis has at least 5 major problems
• Omega-3 reduced time in hospital and atrial fibrillation after cardiac surgery – meta-analysis
• Magnesium treats diabetes and cardiovascular problems – meta-analysis
• Adding Calcium does NOT cause cardiovascular problems (reverses their meta-analysis)
• 800 IU Vitamin D does not help heart – meta-analysis
• Shift workers 23 percent more likely to have cardiovascular events – meta-analysis
• Chronic Heart Failure not treated by Vitamin D, if dose size is ignored – meta-analysis
• Low density lipoprotein cholesterol is predictable from vitamin D levels – meta-analysis
• Statin pain associated with 10 ng less vitamin D – meta-analysis
• Half as many heart deaths for those with high levels of vitamin D – meta-analysis
• Cardiovascular disease 50 % more likely if low vitamin D - meta-analysis
• Magnesium prevents cardiovascular events – Meta-analysis
• Omega-3 does not help heart patients – meta-analysis
• Calcium without vitamin D increased heart risk by 30 percent
• Meta-analysis unsure if vitamin D can prevent cardiovascular disease
• If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT
• Cardiovascular Disease risks reduced by weekly 50,000 IU Vitamin D - RCT Dec 2025
• Heart attack risk halved in adults with heart disease if >40 ng level of vitamin D (RCT)
• Earthing proven by RCTs to work - improves sleep, reduces blood viscosity, etc.
• Seniors with Heart Failure helped by daily 4,000 IU of vitamin D (increase 16 ng) – RCT
• Chronic Heart Failure reduced by 4,000 IU daily for a year – RCT
• Should not add rock Calcium to Vitamin D (after 20 year followup: 6% increase in heart problems – no surprise) – RCT
• Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT
• Afib in Finland reduced 30% by Vitamin D (3200 IU) – RCT
• 3,200 IU of daily not help much in population already having 30 ng of Vitamin D – RCT
• Atrial Fibrillation risk reduced by 0.84 in those raising Vitamin D levels above 30 ng – RCT
• 50,000 IU of Vitamin D weekly for 6 months after cardiac failure helps – RCT
• Monthly vitamin D helped hearts with low vitamin D a bit (need it more frequently) – RCT
• Off Topic: EDTA similar reduction in heart attack as Vitamin C, aspirin and Mg – RCT
• Cardiovascular Disease prevented by Vitamin K2-4 when enough is used – RCT review
• 50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014
• Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT
• Open Heart Surgery associated with low vitamin D, but not if 150,000 IU before surgery – RCT
• Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT
• Anemia (in heart failure) not treated by Vitamin D (they should have added Iron) – RCT
• Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT
• Heart Failure not helped by Vitamin D (several strange things about the trial) – RCT
• Why 100,000 IU of vitamin D monthly did not reduce Cardiovascular Disease – RCT
• Decreased need for warfarin after Vitamin D levels optimized – RCT
• Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT
• Heart failure markers reduced by 400 IU of vitamin D and Calcium (surprise) – RCT
• More blood was pumped by those getting 800,000 IU of vitamin D after heart failure – RCT
• 4000 IU vitamin D daily for just 5 days reduced inflammation after heart attack – RCT
• 1700 IU vitamin D for a year provided no cardiovascular benefit (no surprise) – RCT
• Chronic Heart Failure helped with 2,000 IU of vitamin D (PRA reduced) – RCT
• Fewer deaths (All-cause, Cardiovascular, Cancer) when Vitamin D levels are above 36 ng
• Cardiovascular Benefits: Nattokinase vs. Vitamin D vs. Vitamin K2
• Does C-Reactive Protein increase modestly with vitamin D
• Vitamin D Binding Protein and Coronary artery disease
• Coronary Heart Disease 57 percent more likely if poor Vitamin D Binding Protein with high PTH
• Risk of Cardiovascular disease increased 2X if both low vitamin D and high C-reactive protein
• Heart Disease 40 percent more likely in women having poor Vitamin D Binding Protein
• Vitamin D reduces inflammation (heat shock protein)
• Atrial Fibrillation strongly associated with some vitamin D binding protein
• Not all statins increase vitamin D levels
• Statins with low vitamin D increased chance of musculoskeletal pain by 2X
• 35 tissues activate Vitamin D locally (Kidney not required)
• Heart Failure 35% more likely if their mother had diabetes while pregnant 27 years before
• Heart attack deaths increased 62% in young women in just 11 years - Feb 2026
• Microplastics increase the risk of Colorectal Cancer by 11x, Heart attack by 4X, etc.
• Zinc reduces the risk of Cardiovascular Inflammation
• Vitamin D decreases incidence of disease
• Glutathione fights: Diabetes, Alz, PD, NAFLD, Kidney, UC, IBD, HIV, Fatigue, etc,
• Glutathione benefits \"virtually every physiological system\"
• Low Vitamin D – 2X more likely to have preemie AND mother later to have heart problems
• Liposomal Glutathione works fast - 2 weeks @ 500 mg daily
• Vitamin K-7 needed to keep Calcium out of soft tissues - Dec 2025
• Reduction in cardiovascular death: Coca: -26, Statins -13
• Vitamin D and Cardiovascular Health - 2025
• 99% of Cardiac events are associated with 4 risk factors (Vitamin D can help)
• Health Problems Associated with Low Vitamin D at Birth
• 2.2 X more likely to die if low Vitamin D (Thromboembolism in this case)
• Afib increase by 3X for the 1 in 16 people having poor genes (example of health problem)
• Adult heart problems 2 X more likely low vitamin D 23 years earlier
• What can Vitamin D learn from Baby Aspirin
• Top 10 health problems worse since COVID-19
• Corpses with fiberous clots: 0% before COVID, 30% in 2022, 20% in 2023
• Review of other Vericose Vein treatments (VitD, Horse Chestnut, Disomine, DMSO, etc.)
• Vitamin D fights Coronary Artery Disease in many ways – when will it be used in therapy
• Myocarditis: COVID mRNA is the largest drug cause
• Higher risk of Hypertension, Diabetes, and Stroke if near large body of water (microplastics)
• Afib has doubled, perhaps due to Porphyromonas gingivalis in gums, which is fought by Vitamin D
• Poor oral health increases CVD risk if low Vitamin D
• ALL of the top 10 health problems of women are associated with low vitamin D
• Cardiovascular disease and Vitamin D ( Mendelian analysis again)
• Cardiovascular trials using under 2100 IU of Vitamin D for less than 91 days found little benefit
• Sunlight or UVA provide cardiovascular benefits (NO dialates the vessels) – Weller
• Vitamin D, minerals (Mg, Ca, K, Phosphate, Na, Fe, Zn, Cl, Se) and health – 15 studies 2024
• 5X lower Cardiovascular death rate in regions consuming more fish and vegetables, (and lower obesity)
• Carotid plaques predicted by if low vitamin D (2X higher risk)
• Major heart problems if have less than 15 ng of Vitamin D
• How vitamin D benefits normal organs and Long-COVID organs
• Cardiovascular
• Vitamin D reduces autoimmune, cardio, and metabolic Inflammation
• Vitamin D Has No Effect on Cardiovascular Health (20 studies disagree)
• Problems following surgery if low Vitamin D (Cardiac in this case)
• Vitamin D improves Cardiovascular Health in 8 ways
• More Ultraviolet Radiation, Less Cardiovascular Disease
• Hypothesis - Dysfunction of Autonomic Nervous System is associated with low vitamin D
• Heart problems in submariners (they appear to be unaware of a 60 year old UVB solution)
• Five indicators of poor heart health are 3X more likely if low vitamin D
• Afib implants (cardiac resynchronization therapy) are 3X less likely to help if low vitamin D
• Heart cells may be repaired by vitamin D (nanosensors observed nitric oxide in dish)
• Heart Failure patients 4 X less likely to benefit from pacemaker (CRT) if low vitamin D
• Cardiac resynchronization therapy is 3.3 X less likely to help if low Vitamin D
• DNA analysis of genes (Polygenic risk) shows increased risk of 9 health problems (all 9 fought by Vitamin D)
• Low levels of vitamin D associated with all cause mortality
• Sudden Cardiac Arrest 10.8 X more likely if severe vitamin D deficiency
• Cardiovascular Disease plus Stroke will cost the US a Trillon dollars annually by 2032 (Vitamin D not mentioned) – AHA
• How Vitamin D might reduce cardiovascular diseases
• Omega-3 reduces many aspects of heart problems
• Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help)
• Salmon intervention (vitamin D and Omega-3) improved heart rate variability and reduced anxiety
• Vitamin D reduces CVD by reducing Manganese and Cadmium in blood
• Risk of Cardiovascular death decreased 5X (lowest to highest Vitamin D level)
• Depression with low vitamin D increased risk of CVD and Cancer deaths
• Risk of Cardiovascular disease: Low Vitamin D, low HSPCs and high hsCRP
• 26 health factors increase the risk of COVID-19 – all are proxies for low vitamin D
• 800x Higher Incidence of Myocardial Injury After Booster Vaccination
• Low Vitamin D associated with CHD, stroke, death, etc, (Mendelian analhysis)
• Male preemies had poor heart rate regulation as adults (preemies have low vitamin D)
• Postmenopausal women half as likely to have a cardiovascular death if high vitamin D (NHANES)
• Vitamin D Mistake to Avoid (Heart: Govt say 600 IU, research says 5,000 IU)
• 2 reasons doctors not aware of post-vaccination myocarditis (2.5% of jabs)
• Timeline of Heart Disease, Diabetes, fats, lard, HFCS, and vitamin D
• Metabolic Syndromes fought by Vitamin D in 6 ways
• Nitric oxide increased by UVA, Vitamin D, Magnesium, etc,
• Nitric oxide (from Sun, UVA, Vitamin D) reduces cardiovascular problems
• UV reduces cardiovascular and metabolic problems– Vitamin D plus Nitric oxide
• Vaccine Clinical Trial - cardiovascular death 3.7X more likely if vaccinated - preprint
• Less likely to die of various causes if higher Vitamin D (data from 300,000 people)
• Global burden of brain disorders surpasses cardiovascular disease and cancer
• Cardiovascular events – need more than monthly 60,000 IU vitamin D to prevent other than infarction
• 3X less risk of Atherosclerotic Disease if good level of Vitamin D (Japan)
• Magnesium Suppresses Formation of Clogged Arteries
• 4 Cardiovascular diseases are associated with little vitamin D getting to cells
• Cardiovascular Disorders – 31 recent Vitamin D studies
• Childhood Cancer Survivors have worse arteries due to anticancer therapy
• Atrial Fibrillation - now 1 in 45 in the UK
• Vitamin D both reduces CVD directly and reduces metabolic problems that cause CVD
• Death rates of Cardiovascular patients keep decreasing until 90 nmol of Vitamin D
• Vitamin K reduces calcification (reported yet again)
• Vitamin D not improve health if any of 7 errors are made by trials
• Calcium supplementation associated with 3.9X increase risk of atrial fibrillation
• Those raising Vitamin D above 30 ng were 1.4 X less likely to die of Heart Attack (VA 19 years)
• Poor heart rate variability for a year after Bariatric surgery if low vitamin D
• Cardiovascular problems are prevented by Vitamin D plus Omega-3
• Airline pilot heart annual EKGs - 1 in 5 would have failed test if FAA had not changed the criteria
• High dose vitamin D fights Folate gene changes by COVID, autoimmune, CVD, ALZ
• Athletic deaths now 7 X higher than normal
• Health problems are related to birth month
• Cardiac syndrome X (Microvascular angina, a type of chest pain in women)
• Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU)
• Yet another heart problem, Cardiac X syndrome, is associated with low vitamin D – 2016
• Cardiac syndrome X patients have very low vitamin D levels
• Inflammatory diseases: review of vitamin D, with many tables
• Heart patients 10 percent more likely to die for every 4 ng less vitamin D
• Vitamin D and neurocognitive function – Holick
• Antidepressants reduce cellular Vitamin D, increasing fractures, CVD, etc.
• Surgeries to re-establish blood in brain, heart, etc. are far more successful with high Vitamin D levels
• Coronary Artery Disease Chest Pain, Anxiety, and Fatigue associated with low vitamin D
• Metabolic Syndrome with low vitamin D increases CVD mortality by 1.7 X
• Early menarche, miscarriage and stillbirth are associated with heart disease (all are associated with low Vitamin D)
• Atrial Fibrillation - remineralize your heart
• Ablation does not reduce atrial fibrillation (CABANA study) but Magnesium does
• Cardiovascular disease 2.3 X more-likely if poor Vitamin D Receptor
• Heart problems in obese increase if deficient in BOTH Vitamin D and Magnesium
• Half of Women Over 50 Desperately Need This Potent Nutrient (Vitamin D)
• More Magnesium needed to decrease diabetes, cardio, HT (body weight has increased)
• COVID and CVD deadly pandemics share a risk factor: low vitamin D
• 1.7 X less risk of Heart Failure death if previously had taken any amount of vitamin D
• Resveratrol fights Parkinson, Alzheimers, Diabetes, Cardiovascular, ALS, Stroke, etc.
• Giving free vitamin D to every Iranian would pay for itself by just reducing CVD
• Inflammation of blood vessels (vasculitis): low Vitamin D and 22 X more likely to have kidney problems
• Omega-3 decreases heart disease and COVID: Harris and Patrick, video and transcript
• Sudden cardiac arrest 6X worse outcome if low vitamin D
• Sudden Cardiac Arrest – 2.8 X higher risk if low vitamin D – 2019
• CPR with low vitamin D – 10X more likely to have poor outcome within 3 months
• Death in less than 2 years of Heart Failure associated with low vitamin D
• Vitamin C is as good as exercise at reducing cardiovascular problems
• Vitamin D levels dropped 42 percent immediately after pediatric cardiac surgery
• Vitamin D probably has a Role in Cancer, CVD, and COVID - video and transcript
• Vitamin D level of 20 ng does not prevent cancer, CVD, Diabetes, etc (not a news item)
• Heart Failure 15X more likely if poor VDR, even if good level of vitamin D (China)
• Low Vitamin D and Vitamin K: brittle bones and hardened arteries – LEF
• Atrial fibrillation - Vitamin D improved 1 of 4 measures
• Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues
• Getting Vitamin D before heart surgery prevented Afib in those who had been deficient
• Atrial fibrillation and low vitamin D: both types of AF are very low
• Thalassemia (low hemogloben problem) and Vitamin D
• Higher Omega-3 index (4 to 8 percent) associated with 30 percent less risk of coronary disease (10 studies)
• Cardiovascular disease and vitamin D (some strange claims)
• Growing consensus: COVID-19 symptoms are due to infected blood vessels
• Bone loss results in blood vessel plaque if low Vitamin K2, less bone loss if high K2
• COVID-19 hospitalizations: 63% associated with diabetes, obesity, hypertension or heart failure
• Coronary Artery Disease 2.9 X more likely in postmenopausal women if Vitamin D deficient
• Hypothesis: Vitamin K will reduce prostate blood vessel problems
• 50,000 IU of Vitamin D weekly for 9 weeks did not improve CVD
• 1.3X higher risk of severe Cardiovascular and Cerebrovascular problems if low Vitamin D (50 million people)
• Vitamin D deficiency associated with increased risk of many health problems in 58,000,000 Americans
• After Heart Failure Blacks are 45 percent more likely to re-enter the hospital in a month
• Blackouts due to low blood pressure associated with 8 nanograms lower vitamin D
• UVB phototherapy (which increases Vitamin D and VDR) decreased risk of many heart and stroke problems
• Omega-3 reduced cardiovascular deaths by 16 percent (427,678 people)
• Heart Failure may be associated with low Zinc (drugs and gut restrict Zinc)
• Synthetic EPA drug recommended to FDA for Cardio (Omega-3 is 8 X better)
• Senior veterans with Heart Failure were 1.8X more likely to be hospitalized if low vitamin D
• Heart attack ICU costs cut in half by Vitamin D
• Arterial stiffness reduced by Omega-3, Vitamin D, Vitamin K2, Magnesium, etc.
• Arterial stiffness reduced by vitamin D
• Stiff arteries in seniors associated with low vitamin D levels
• Heart Attacks in men 13 percent more likely if 10 degrees further North (Sweden)
• Resveratrol and Cardiovascular Diseases
• Acute Coronary Syndrome is associated with poor Vitamin D genes (CYP27B1, CYP24A1)
• Statin side-effects are reduced by Vitamin D – US patent Application
• Preeclampsia (low vitamin D) doubles the risk of later cardiovascular problems
• The health benefits of vitamin K
• Signs of low Magnesium (heart problems in this case)
• Cardiovascular Prevention with Omega-3 (finally using high doses)
• Perhaps the Omega-3 optimal level is 10 percent, not 8
• Statins associated with 14X increase in Polymyalgia Rheumatica (a new disease)
• Preterm birth increases risk of heart disease by 1.5 X by age 40
• Statin pain eliminated by 7100 IU vitamin D (50000 IU weekly)
• Few people have enough EPA (an Omega-3) to reduce heart failures
• Peripheral Arterial Disease 3.7 X more likely in diabetics with low vitamin D
• Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
• Football professionals die more often of neuro and cardio problems than those in baseball
• Calcium Supplementation is OK provided you also take Vitamin K
• Bone marrow failure (MDS) is associated with half as much Vitamin D
• Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K)
• Extreme Heat Events increase congenital heart defects (perhaps low vitamin D)
• Increased Vitamin K2 reduces the problems of excess Calcium
• Metabolic Syndrome associated with low vitamin D in abdominal obese women
• Vitamin D protects against many types of health problems – review
• Congestive Heart Failure patients helped with Vitamin D intervention
• Cardiovascular death 40 percent more likely in a decade if chest pain and low Vitamin D
• Congenital Heart problems - vitamin D levels drop even lower after surgery, loading dose probably required - thesis 2015
• Higher Cardiovascular fitness (VO2) if higher Vitamin D
• Exercise capacity (VO2) 25 percent higher if high level of vitamin D
• Subclinical Heart injury in men 1.7 more likely if low vitamin D
• Omega-3 provides many cardiovascular benefits
• Far fewer health problems from western diet if add Vitamin D (in rats in this study)
• Cardiovascular disease is treated by vitamin D, unsure if low Vit D can predict Cardio
• Heart Failure is predicted by PTH (but vitamin D both prevents and treats HF)
• Vitamin D and Vitamin K together fight CVD Part 1- Pizzorno
• Vitamin K, Cardiovascular and interactions with Vitamin D and Vitamin A – Pizzorno
• Reduced changes in heart (LVAR) and 2X more survive after heart attack if higher vitamin D
• Kidney problems reduces Vitamin K. which causes cardiovascular problems
• Off Topic - EECP reduces rehospitalization after heart attack by 3X, paid by Medicare
• 17 percent more heart attacks in the winter (perhaps due to low vitamin D)
• Hypothesis – Vascular calcification is associated with both too much and too little vitamin D
• Atrial fibrillation reduced with modest vitamin D levels (did not consider Magnesium)
• Another Nail in the Coffin for Fish Oil Supplements (nope) – JAMA
• Omega-3 helps the heart, AHA class II recommendation, more than 1 gm may be needed
• Heart failure among 137 seniors 12X more likely if low vitamin D
• Benefits of Omega-3 beyond heart health - LEF
• Cardiovascular disease predicted by CRP and vitamin D, not cholesterol
• Off Topic – EMT diagnoses Heart Attacks correctly 73% of the time in the US, 95% correct if use A.I.
• Lipoprotein(a) triples the risk of heart attack or stroke unless add Vitamin D, etc.
• Stroke or coronary heart disease deaths 30% less likely if had taken more than 440 IU of vitamin D (900,000 patient years)
• Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium
• 24X less Calcification of Aorta for PAD with modest level of vitamin D
• Fast blood flow 6.8 X more likely if high vitamin D AND high vitamin K
• Congenital heart defects twice as likely if low vitamin D while pregnant
• Omega-3 is vital for health, mail-in test is low cost and accurate
• Heart disease 2.9 X more likely if essential hypertension person has low vitamin D
• Cancer diagnosis increased cardiovascular death 5 X in the next week – 2012
• Striking ethnic health disparity – blacks dying due to lack of vitamin D
• Mortality associated with Vitamin K insufficiency (PREVEND Study)
• Cardiometabolic risk reduced by Omega-3 - dissertation
• Review of role of Vitamin D in Cardiometabolic diseases
• Hypothesis - Low Vitamin D causes Cardiovascular diseases
• Off topic: Heart surgery in afternoon has half the complications
• Cardiac Surgery and active vitamin D – quickly dropped by 29 percent, 6 more days in hospital if deficient
• Heart Attack increased risk of vascular dementia by 1.35 X (both associated with low vitamin D)
• Risk that Heart does not pump enough (ejection fraction) is 2.5 X more likely if low vitamin D
• For every Omega-3 dollar there is a 84 dollar savings in Cardiovascular costs - Foster and Sullivan
• Coronary Artery Disease risk both increased and decreased by 30 percent with mutations in Vitamin D Binding
• Peripheral Arterial Disease 2 percent more likely for every 1 nanogram less Vitamin D
• Vitamin D and peripheral arterial disease
• Can vitamin D improve quality of life for seniors with heart failure -2010
• Cardiovascular Diseases associated with both Vitamin D and innate immune system (TLR)
• Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
• Depression in cardiovascular patients is associated with less than 15 ng vitamin D
• Heart Failure with depression increases risk of death by 9.5 X if low vitamin D
• Acute Heart Failure length of stay and readmission rates cut in half if high vitamin D
• Chronic Heart Failure – not enough evidence that Vitamin D helps (but lots of evidence for other cardiovascular problems)
• Obstructive coronary artery disease 2.9 X more likely if chest pain and low vitamin D
• Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D
• Cardiovascular diseases – conflicting data on benefits of Omega-3 and vitamin D
• Vitamin D augmented conventional Congestive Heart Failure treatment in perhaps 10 ways – case reports
• Low Vitamin K2 is as risky as smoking for heart disease
• 7X increased chance of death if coronary artery disease and low vitamin D
• High dose Omega-3 probably reduces heart problems – American Heart Association
• New blood vessels (angiogenesis) is regulated by Vitamin D – 2016
• Vitamin D reduces chance of a second heart attack and death
• Acute Coronary Syndrome twice as bad if low vitamin D
• Smoking associated with 2 times fewer heart problems if high vitamin D
• Higher vitamin D levels associated with fewer vein clots decades later
• Almost 6X more likely to die after coronary bypass if vitamin D deficient
• Chance of death after heart failure reduced by 1000 IU of vitamin D
• 3 X increased chance of death if have asthma – study of 200,000 people over 10 years
• Cardiovascular death reduction in dark skin migrants by just 1,000 IU of vitamin D
• Less than 900 IU of Vitamin D and Calcium do not cause cardiovascular problems
• Baby aspirin reduces heart problems - Vitamin D much better
• Vitamin D for the Prevention of Cardiovascular Disease: Are we ready for that
• Atherosclerosis prevented by Ultraviolet light (UVB in mice)
• Hypothesis: Atherosclerosis in Ancient and Modern Humans due to low vitamin D (behind paywall)
• Atherosclerosis – higher risk due to low vitamin D than HDL
• Omega-3 – need more than 1 gram for a short time to reduce Cardiovascular Disease
• Cardiovascular death: 9 percent due to hypertension or air pollution, 7 percent: low Vitamin K2 or smoking
• Why is too much vitamin D bad for bad hearts
• 800 IU of vitamin D is not enough to help Cardiovascular Disease (found again)
• More than 800 mg of Calcium increases Cardiovascular events by 85 percent
• High maternal vitamin D resulted in 12 percent less inflammation (CRP) 20 years later
• Coronary artery calcification associated with low vitamin D
• Cardiac rehabilitation had more power if more than 20 nanograms of vitamin D
• Coronary Heart Disease 3 times more likely if endometriosis before age 40 (vitamin D not mentioned)
• Heart problems are reduced with vitamin D – Heart month
• Hypothesis: increased vitamin D will increase erections and decrease CVD
• Cardiovascular Disease and vitamin D – no proof yet
• Psoriasis is associated with kidney disease, heart problems, diabetes, etc
• Cardiovascular Disease and Diabetes helped by Vitamin D – most 2013-15 studies agree
• More vitamin D makes for better health – dissertation based on Rotterdam studies
• Peripheral Arterial Disease 3X less prevalent at 40 ng of vitamin D – 2008
• Vitamin D not associated with PAD after adjusting for race, diabetes and BMI
• Links between Vitamin D Deficiency and Cardiovascular Diseases
• Cardiovascular Diseases and Vitamin D – Review
• 2X more complications after heart surgery associated with high level of vitamin D
• Cardiovascular system benefits from both Omega-3 and vitamin D
• Vitamin D, the autonomic nervous system, and cardiovascular risk - Editorial
• Higher vitamin D levels associated with health and lower risk of atrial fibrillation
• One statin decreased vitamin D levels but the other did not
• 7100 IU vitamin D2 for 3 months did not treat Coronary Artery Disease
• Athletes (national-level) with less than 10 ng of vitamin D had smaller hearts
• Active vitamin D decreased atrial fibrillation occurrence by 9X and duration by 77X (rabbits)
• Heart Failure early death 2X more likely if less than 20 nanograms of vitamin D
• Children with low vitamin D were 1.8 X more likely to have poor arteries 27 years later
• Vitamin D Deficiency may be an Independent Risk Factor for Arterial Disease
• High triglyceride and cholesterol associated with low vitamin D in postmenopausal women
• Vitamin D and CVD - potential mechanisms and novel perspectives - 2013
• Types of vitamin D, African American teenage girls, and measures of heart fitness
• Table of outcomes for seniors vs vitamin D level
• Coronary Artery Enlargement associated with low levels of vitamin D
• Hypothesis: Diabetes association with CVD is via Vitamin D
• Fewer heart attacks, hip fractures and deaths if more skin cancer
• Yet again – 1700 IU vitamin D average does not reduce heart problems
• 92 percent had low vitamin D before heart surgery
• Major Heart attacks occur 40 percent more often if vitamin D lower than 7 ng
• Major ECG abnormalities associated with low vitamin D and death
• Omega-7 - in addition to Omega-3
• Cardiovascular Disease is associated with lack of Vitamin D - meets most of Hill's Criteria
• Omega-3 reduces Coronary Heart Disease - infographic
• Potential for vitamin D receptor agonists in the treatment of cardiovascular disease
• Hearts responded to stress better after 5,000 IU of vitamin D for a month
• Coronary artery disease extent is associated with extent of vitamin D deficiency
• Atherogenesis, atherosclerosis and vitamin D – review
• Youthful heart attacks associated with low vitamin D
• Cardiovascular Disease and vitamin D – review 2013
• Heart is helped by Vitamin D in many ways, still unsure about dose size
• Aortic Calcification 85 percent more likely if vitamin D level lower than 29 ng
• Is excess calcium harmful to health - 2010
• Atrial Fibrillation associated with lower levels of vitamin D
• Vitamin D is not a cardiovascular fad like Vitamins C, E, Folic Acid, selenium, beta-caroteen, etc. – Circulation
• Protective cardiovascular and renal actions of vitamin D and sex hormones
• Heart pumped more blood after heart failure if more vitamin D
• Vitamin D significantly lowers macrophage adhesion to prevent arterial clots (in diabetics)
• Cholesterol, Vitamins D3 and K2, heart disease, sulfates, LDL, – Masterjohn Interview
• Coronary artery disease 5.8X more likely if vitamin D level is less than 30 ng
• Vitamin D deficiency is an independent cardiovascular risk factor
• Large abdominal aortic aneurysm 5.4X less frequent if have lots of vitamin D
• Increased probability of chest aorta aneurisms with low vitamin D
• Hypothesis: Low maternal vitamin D increases probability of heart disease later in adult
• Heart Damage and low vitamin D greatly increases chance of dying
• Heart attacks did not reduce vitamin D levels
• Faster heart rate and higher systolic blood pressure associated with low vitamin D
• Vitamin D accounts for 25 percent of the racial differences in blood pressure
• Death from Coronary Heart Disease related to low Magnesium intake
• Heart failure 2X more likely if less than 20 ng of vitamin D
• Lacking data, claimed evidence of cardiac probems if too much vitamin D
• Petrie dish experiment confirms that active vitamin D reduces arterial inflammation
• More than 400 mg of Calcium supplements caused cardiovascular deaths in men
• Predicted cardiac surgery death associated with low vitamin D levels
• Low vitamin D is a risk factor for vascular diseases in African Americans
• Low vitamin D increases risk of cardiovascular disease in African Americans – 2011
• 14X more likely to die after first cardiovascular event if vitamin D deficient
• Vitamin D level higher than 30 ng reduces diabetic blood clotting
• Vitamin D associated with tPA (heart) for 50 year olds in UK
• 50000 IU vitamin D2 weekly helped blacks with heart problems
• Cardiovascular risk factors in children associated with low vitamin D
• Studies linked low vitamin D and dark skin to Obesity, Diabetes, and heart
• Off topic: CVD: the primary cause of death in senior women, is increasing
• Increased heart attacks in the winter may be due to lack of sunshine
• Best heart geometry associated with vitamin D of 30-37 ng
• 2500 IU vitamin D did not reduce risk of CVD risk in 4 months
• Vitamin D reduced CVD risk - systematic review 2010
• Hypertension experts want still more vitamin D proof
• Vertebral fracture 3X more likely with aortic calcification – Vitamins D3 and K2
• 800 IU Vitamin D doesn't prevent heart attack or cancer
• Coronary Artery Disease predicted by low levels of vitamin D
• Echocardiograms confirm problems with low vitamin D
• 100000 IU vitamin D did not help Peripheral Arerial Disease in one month
• 1000 IU vitamin D did not reduce cardiovascular risk factors
• Cardiovascular Disease and vitamin D
• High triglycerides in Metabolic Syndrome associated with low Vitamin D
• UVB increasing vitamin D to 34 ng did not lower blood pressure
• Babies Receive Heart Transplants Instead of Vitamin D Treatment
• 11 ng less vitamin D increases hypertension probability by 14 percent
• CVD deaths related to low vitamin D, especially in people with dark skin – 2010
• Did not find association between vitamin D and cardiovascular mortality
• Vitamin D interactions with cardiovascular disease - unsure
• 96 percent of heart failure patients had less than 30 ng of vitamin D
• Abu Dhabi 2012 - Grant
• Old concern about high vitamin D and atherosclerosis – 2003
• Statistical paradox of vitamin D deficiency and heart disease
• Vitamin D deficiency highly correlated with cardiovascular problems
• Heart Failure associated with vitamin D deficiency
• Vitamin D deficiency might cause diabetes and cardiovascular diseases
• Cardiovascular problems for teens if low levels of vitamin D
• Low vitamin D associated with obesity-related diseases for ethnic minorities
• Hypothesis: Vitamin D will decrease CVD and diabetes in African Americans
• Vitamin D helped cardiovascular patients in many ways
• Yup, 2500 IU of vitamin D does not help the heart in the short term
• Cardiovascular disease may be reduced by vitamin D
• Review of Calcium – Vitamin D - Cardiovascular Disease
• Low vitamin D may contribute to Peripheral Arterial Disease
• More than 600 IU of vitamin D reduced male CVD risk by 16 percent
• Improved blood flow in blacks with just 2000 IU of vitamin D
• Lack of vitamin D associated with many cardiovascular problems
• Vitamin D relationship with HDL and LDL is uncertain
• CV event 56 percent more likely after vascular surgery if low on vitamin D
• Bypass surgery and vitamin D
• Calcium can create heart problems - vitamin D neutral
• Vitamin D is a promising way to deal with atherosclerosis
• Atherosclerosis associated with low vitamin D
• Vitamin D might deal with atherosclerosis
• Increasing vitamin D levels will probably reduce CVD and mortality
• Patent for patients of Chronic Heart Failure includes vitamin D
• Monkeys each got 1000 IU daily - but vitamin D in blood varied with HDL
• Not yet certain that vitamin D reduces cardiovascular and diabetes in blacks
• Review is unsure if supplementing vitamin D will decrease heart failure
• Question - Does more vitamin D make veins less stiff
• Calcium with Vitamin D2 then D3 helps A-A after heart failure
• Why we need large-scale heart trials of vitamin D
• Editorial on Vitamin D deficiency– Current Drug topics
• Review of heart failure and vitamin D mechanisms
• Vitamin D reduces both death rate and cardiovascular disease
• Heart Failure 3X more likely if less than 30 ng of vitamin D
• Review of vitamin D and heart failure
• Lack of vitamin D is a predictor of heart failure
• Twice as likely to die of cardiovascular disease if low on vitamin D
• Heart attacks increased by 30% in those taking 500 mg of Calcium without vitamin D
• The prognostic value of vitamin D in heart failure
• Aortas of 16 year old blacks helped by 2000 IU of vitamin D
• 40% more likely to die of heart problems if have low level of vitamin D
• Vitamin D and cardiovascular disease - Systematic review
• Cardiovascular Systematic Review of Vitamin D
• Low Vitamin D associated with cardiovascular disease
• Vitamin D lower than 15 ng associated with almost 3X more depression in seniors with CVD
• Vitamin D less than 15 ng did not predict additional cardiovascular disease events
• Vitamin D deficient elderly are 2X more likely to die of CVD
• 5700 IU daily equivalent vitamin D for obese did not reduce cardiovascular risk factors
• Vitamin D deficiency associated with many diseases – Greece
• 1000 IU vitamin D might prevent cardiovascular events
• CVD 2X more likely if less than 10 ng than if greater than 30 ng
• The impact of vitamin D deficiency on diabetes and cardiovascular risk