Pages tagged with "Trauma and Surgery"

369 pages, most important first (overviews, then meta-analyses, then RCTs, then newest). Combine with another topic

• Traumatic Brain Injury treated by Vitamin D - many studies
• With just 200 IU vitamin D in intravenous feeds, deficiency results
• Low vitamin D before orthopedic surgery – dark skin 5X more likely
• Burns, ulcers, and wounds healed by Vitamin D - many studies
• Military and Vitamin D - many studies
• Total knee arthroplasty – worse outcome if low vitamin D – many studies
• Superbug (Clostridium difficile) Infections strongly associated with low vitamin D - many studies
• Thyroidectomy and Vitamin D - many studies
• Sepsis is both prevented and treated by Vitamin D - many studies
• Bariatric Surgery and Vitamin D - many studies
• Middle ear infection (Otitis Media) and Vitamin D – many studies
• Delirium more likely if low vitamin D - many studies
• ICU patients typically benefit from 300-500,000 IU of Vitamin D - many studies
• Vitamin D is needed before many surgeries – many studies and RCTs
• Orthopaedic surgeries need Vitamin D – many studies
• ACL knee problems assocated with low Vitamin D - several studies
• Anesthesia can cause cognitive problems in elderly with low vitamin D - several studies
• Rotator cuff and Vitamin D - several studies
• Earthquake and Vitamin D - several studies
• Critically ill patients who received 300,000 IU of Vitamin D were 40% less likely to die within a month - meta-analysis
• ICU trials typically use 300,000 IU of Vitamin D - meta-analysis
• Risk of AFib after Cardiac surgery cut in half by 200,000+ IU Vitamin D meta-analysis
• After Spinal Fusion, Vitamin D is better than Bisphosphonate Therapy at 1 year - meta-analysis
• Vitamin D before surgery helped again (Thyroid in this case) - meta-analysis
• If low vitamin D before orthopedic surgery, then 1.5 X increased risk of cardiac event (MACE) – meta-analysis
• After bariatric surgery all of the fat-soluble vitamins are lacking (Note: other forms of the vitamins are much better) – meta-analysis
• Vitamin D and the Critically Ill - meta-analysis
• Sepsis 2X-3X more likely if poor Vitamin D Receptor – meta-analysis
• ICU patients 30 % less likely to die if have enough vitamin D – meta-analysis
• Afib 40% less likely after heart by-pass if have enough Vitamin D – meta-analysis
• ICU Vitamin D supplementation not help (study ignored level achieved) – meta-analysis 2022
• Delirium or cognitive problems after surgery 1.5X more likely if low vitamin D –meta-analysis
• 4 fewer days in hospital after hip or knee replacement if good level of vitamin D
• ICU mortality reduced by non-oral vitamin D – meta-analysis
• Fewer days in ICU after 300,000 IU of vitamin D, but not 540,000 – meta-analysis
• Vitamin D loading doses reduce ICU mortality by 30 percent – meta-analysis
• Sepsis: 4 fewer days in ICU if add Omega-3 – meta-analysis of 12 RCT
• Septic children have low Vitamin D (54 studies, ignored Vitamin D Receptor) – meta-analysis
• Active form of vitamin D (calcitriol) cut in half the fractures following organ transplant – meta-analysis
• ICU length of stay reduced when supplement with Omega-3 – meta-analysis
• Critically ill children with low vitamin D: 2.5 X more likely to die or stay 2 days longer - meta-analysis
• 2.7 fewer days in hospital after surgery if had taken Omega-3 (19 RCT) – meta-analysis
• Omega-3 reduced time in hospital and atrial fibrillation after cardiac surgery – meta-analysis
• Surgical outcomes are better for higher levels of Vitamin D – systematic review
• 1.5X increased infection, sepsis, and death if in ICU with low vitamin D - Meta-analysis
• Severe sepsis may be prevented by 400,000 IU of vitamin D – RCT 2023
• Half as much AFIB after bypass if 600,000 IU of vitamin D before surgery – RCT
• Esophageal Cancer surgery helped by 300,000 IU of Vitamin D – RCT
• 14 types of surgeries improved by Vitamin D - RCTs Dec 2025
• Spinal fusion surgery greatly improved by Vitamin K2 - RCT
• ICU patients 6X more likely to die if poor response to 570,000 IU of Vitamin D – RCT
• Surgery complications cut in half by 300,000 IU of vitamin D 2 weeks before (hip and knee) – RCT
• Vitamin D loading doses typically helped critically ill, but never harmed (21 RCTs)
• TBI reduced 5X by 300,000 IU of vitamin D (injection) – RCT
• Following sleeve gastrectomy surgery, 3,000 IU of vitamin D daily for a year helped – RCT
• Give ICU children a bolus dose of 10,000 IU of vitamin D per kg – RCT underway
• Sepsis (with mechanical ventilation) treated by 5days of 50,000 IU of Vitamin D – RCT
• ICU Vitamin D injection (300,000 IU) helped - RCT
• 3X less Septic Shock in children with sepsis getting 150,000 IU of Vitamin D - RCT
• Burns - will 200,000 IU of vitamin D decrease hospital stay - RCT 2021
• Half as many problems if take Vitamin D (300,000 IU) before thyroidectomy – RCT
• Taking Vitamin D just before and after surgery helps (open-heart in this case) – RCT
• Candida infections in PICU reduced by Vitamin D in yogurt – RCT
• Fewer days in hospital if 300,000 IU of vitamin D before brain surgery - RCT
• 18 fewer hospital days if given 500,000 IU of vitamin D while ventilated in ICU – RCT
• Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023
• Those getting an injection of 300,000 IU Vitamin D got out of the ICU a week sooner – RCT
• Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT
• ICU adults getting 540,000 IU of Vitamin D were 2X more likely to be alive 30 days later – RCT
• 100,000 IU daily of Vitamin D for 5 days increased Hemoglobin in Mechanically Ventilated adults – RCT
• 10 fewer days of ICU Mechanical Ventilation 300,000 IU injection of vitamin D – RCT
• Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT
• Rapidly restore Vitamin D levels with 10,000 IU per kg for children in ICU – RCT 2024
• Following brain surgery Vitamin D injections did not raise blood levels much – RCT
• 300,000 IU Vitamin D injection before brain tumor surgery – RCT to finish
• VITdAL-ICU - AMA RCT
• Will lots of vitamin D help in ICU – RCT protocol
• Football Brain injuries prevented by Omega-3 – RCT
• Omega-3 supplements taken before and after surgery actually helped – RCT
• Knee replacement not helped by 2,000 IU of vitamin D (both too late and too little) – RCT
• Urinary sepsis – a single Vitamin D injection reduced hospital days by 40 percent – RCT
• Open Heart Surgery associated with low vitamin D, but not if 150,000 IU before surgery – RCT
• Vitamin D aided progesterone in reducing traumatic brain injury – RCT
• Bones helped by Vitamin D, Physical Exercise, etc (this time - Bariatric Surgery) – RCT
• Critically ill injected with 300,000 IU of vitamin D, 3X more likely to die if PTH did not respond - RCT
• Vitamin D intervention increased by 20 percent the survival of critically ill patients- RCT
• Postoperative adhesions reduced in rats supplemented with vitamin D – RCT
• Sepsis is fought by Vitamin D in 9 ways
• Deep vein clots after knee replacement 3X more likely if low vitamin D - cohort
• Plastic and Reconstructive Surgeries apparently improved by Vitamin D
• $371,000 healthcare estimated cost for a couple retiring in 2026— nearly double what the typical household has saved
• Postoperative delirium in children 14X more likely if low Vitamin D (simple laparoscopic surgery)
• Hard-to-heal Wounds associated with low Vitamin D
• Vitamin D, glutathione, and heat shock protein to treat concussions, etc. – US Patent
• 3X less muscle atrophy after ACL surgery if more than 40 ng of vitamin D
• Critically ill children – randomized clinical trial to give single doses of up to 400,000 IU of vitamin D – 2019
• Root Canals healed better in 4 ways if >20 ng of Vitamin D
• Total Hip or Knee Arthroplasty: 4 more days in hospital if low Vitamin D
• 600,000 IU intramuscular D3 helped BMD after pancreatic surgery
• Pre-operative Vitamin D often helps (thyroidectomy in this case)
• 5,000 ICU patients have benefited from Vitamin D
• Surgical Site Infection (Cesarean) twice as likely if low Vitamin D
• More edema after traumatic brain injury if low Vitamin D
• Postoperative problems are reduced if sufficient Vitamin D (Bunion in this case)
• Vitamin D and exercise after hip fracture surgery – far fewer deaths
• Serious respiratory infection 33% more likely if low Vitamin D
• Surgical ICU – 2.7 X more likely go home if OK vitamin D
• Delayed wound healing after surgery if low vitamin D (Carpal Tunnel is this case)
• Vitamin D and neurodegenerative diseases
• Hand surgery complications 43% less likely if have good Vitamin D level
• Muscle strength improved after knee surgery by Vitamin D – 10 studies
• Vitamin D and Liposomal Glutathione restore the immune system
• ICU child deaths reduced when add just 95 IU of Vitamin D
• Vitamin D's Role in Organ Transplantation: Prevention, Outcomes, and Longevity
• Hospitalized with burns - 28% more likely to die if low vitamin D
• Postoperative cognitive dysfunction 8 X more likely if low vitamin D
• Death after surgery for chronic kidney disease 2.3 X more likely if low Vitamin D
• Concussion treatments reviewed - best to nope
• Complications after anesthesia if low on vitamins – example: increased risk of delirium if low vitamin D – review
• Cardiac surgery patients with low vitamin D had worse outcomes (no surprise)
• 400,000 IU of Vitamin D before surgery should cost-effectively reduce infection after knee replacement
• Spinal TB surgery now includes Vitamin D as the standard of care (5,000 IU daily)
• Lung transplant survival 4X more likely if take 2,000 IU of vitamin D daily
• Problems following surgery if low Vitamin D (Cardiac in this case)
• Following Bariatric surgery, weekly 50,000 IU of standard Vitamin D is not enough
• Bariatric surgery increases risk of bone fracture (less vitamin D adsorbed)
• Bariatric Surgery lowered risk of severe liver disease (not a surprise)
• Higher vitamin D helps regain muscle strength after knee surgery
• Hospitalized cats 8X more likely to die if low vitamin D (Vit. D helps humans too)
• 3X reduced mortality in one metabolic cluster of ICU patients by high-dose Vitamin D
• Children in Intensive Care need Vitamin D loading dose of 10000 IU per kg (nearing a consensus)
• ICU - need Vitamin D ASAP - interview and transcript, Matthews
• US Army learning about benefits of vitamin D to trauma – Matthews
• Vitamin D and Glutamine reduced Trauma Center deaths by half – Matthews
• Large dose Vitamin D before surgery was found to help by 35 studies
• Spinal fusion patients often low on vitamin D
• Spinal Fusion complications 2.2 X more likely if low Vitamin D
• Hospital ICU added high dose vitamin D - malpractice lawsuit costs dropped from 26 million dollars to ZERO
• Trauma and surgery
• 4.8 X more likely to die within 28 days of ICU if low Vitamin D
• Improve your health BEFORE surgery (prehabilitation) helps your recovery - 2018
• Vitamin D and Glutamine resulted in 2.6X reduction in trauma center mortality rate
• Vitamin D supplementation helps after obesity treatment
• Critically ill trauma patients - virtually none had even 30 ng of Vitamin D
• Sepsis mortality greater in Black than White children (low vitamin D)
• Vitamin D should improve rotator cuff surgery success rate
• Rotator Cuff repair using Vitamin D lowers medical cost by 46 dollars
• Doctors Still Struggle to Diagnose a Condition That Kills More Than Stroke (Sepsis, Vitamin D helps)
• Rotator cuff repair treatments – all but Vitamin D need a prescription
• Loss of muscle strength –sarcopenia – one of the suspects is vitamin D
• 3,200 IU of Vitamin D for 3 weeks before colon cancer surgery helped a bit (higher or loading dose would be much better)
• Restore your Vitamin D levels before surgery (Gastric Cancer in this case)
• ICU cost reduced by at least 27,000 dollars if get high dose vitamin D in first week
• Vitamin D before surgery improves outcome (spinal in this case)
• Vitamin D should reduce hospital-acquired infections – Grant
• Sepsis patients 2.7 X more likely to die if low Vitamin D
• Little risk of infection after surgery if have more than 50 ng of vitamin D - 2014
• Better Surgical outcomes if preceded by Vitamin D loading dose
• Surgeries more successful if high vitamin D (tympanic membrane in this case)
• Surgical Site Infection 4X more likely if low vitamin D
• Vitamin D before surgery often helps (Thyroidectomy in this case)
• Vitamin D might help critically ill patients (if enough is given quickly)
• More post-operative pain if low vitamin D before ( 2.4 X for Thoracoscopic)
• Before joint replacement surgery low Vitamin D associated with systemic disease
• Surgeries to re-establish blood in brain, heart, etc. are far more successful with high Vitamin D levels
• Hospital or ICU death about twice as likely if low vitamin D
• Chance of dying in hospital cut in half by just 10 ng higher level of Vitamin D
• Surgeries often deplete Vitamin D - 300,000 IU resulted in little response
• 40% less likely to recover from TBI with Intracranial Injury if low vitamin D
• Traumatic Brain Injury recovered faster if high vitamin D (review of 58 studies)
• Hospital induced delirium 2X more likely if low vitamin D
• Delirium in Hospitalized Older Adults (does not mention low vitamin D relationship) NEJM
• Delirium 24 percent more likely for each 2.5 ng lower vitamin D (313,000 patients)
• Vitamin D levels crash after various surgeries (cardiac in this case)
• Vitamin D levels dropped 42 percent immediately after pediatric cardiac surgery
• Congenital heart surgery dropped vitamin D levels by 40 percent
• 2.4 X fewer burn complications if have more than 20 ng of Vitamin D
• Stop - Read This Before You Have Orthopedic Surgery
• Oral Vitamin D much better than injection (after Knee Arthroplasty in this case)
• Poor Receptor predicts sepsis death (restricts Vitamin D from getting to cells)
• Fewer drugs needed after cardiac surgery if higher levels of vitamin D (Chinese children)
• Many Organ transplants cause skin cancer – what is the role of UV
• Vitamin D in Critical care – they agree that 800 IU can be used (far too little)
• Getting Vitamin D before heart surgery prevented Afib in those who had been deficient
• Post-surgery delirium in critically ill 1.4X more likely for each 10 ng lower level of vitamin D (below 30 ng)
• Delirium 2.7 X more likely after hip fracture and low vitamin D
• Give Vitamin D before all spinal surgeries – no testing needed
• 1 in 6 critically ill in India have high levels of vitamin D (100 ng)
• Kidney transplant rejection 1.8X more likely if low vitamin D
• Vitamin D decrease during inflammation is probably due to interferons
• Organ Transplant patients probably need more UV and or vitamin D
• If you are getting a lung transplant you must have vitamin D
• Heart transplant 19 ng vitamin D vs liver transplant 13 ng
• Critically ill need vitamin D – how much and which test to use is TBD
• Vitamin D3 Attenuates Blood-Brain Barrier Disruption due to TBI (in rats)
• Pro-inflammatory cytokines cause the 74 percent drop in vitamin D after knee arthroplasty
• Traumatic Brain Injuries routinely treated by Vitamin D, Omega-3, Progesterone and Gluatmine
• Traumatic Brain Injury recovery helped by injection of 100,000 IU of Vitamin D
• Crohn's Disease 4X less likely to reoccur after surgery if good level of vitamin D
• Adding Vitamin D decreased kidney deaths by 4x
• Almost everyone with COVID-19 in a Louisiana ICU had low vitamin D
• Use of Vitamin D in a trauma surgery - Dr. Matthews on Facebook
• ICU patients greatly helped by Vitamin D loading doses – if gut-friendly
• Vitamin D levels might be raised very quickly
• Intensive Care (ICU) helped by Vitamin D – review of past and on-going studies
• Vitamin D might reduce suture infection when time-released from nano-structure suture
• Vitamin D deficiency in pediatric critical illness: Time to move on from observational studies
• Vitamin D reduces inflammation in critically ill patients
• ICU survival increased with vitamin D single 540K IU loading dose - JAMA
• Surgery outcome worse if low vitamin D (lumbar spine surgery this time)
• Spinal Surgery patients – almost all have low vitamin D
• Vitamin D needed after most spinal surgeries (and before as well) – 2013
• Low levels of vitamin D prior to spine surgery
• Vitamin D reduces trauma injuries in many ways
• ICU was 2X less likely for COVID-19 hospitalization if Vitamin D more than 20 ng
• Cardiac Surgery with low vitamin D increased delirium 1.4X, mortality 1.5X
• ICU death rate reduced 3X when a vitamin D injection changed the PTH
• Vitamin D and critically ill patients (book chapter)
• Vitamin D, trauma, and blacks - Dr. Matthews interview with transcript
• PICU children with low vitamin D levels have worse health scores (PRISM-III)
• Role and Mechanism of Vitamin D in Sepsis (Chinese)
• Vitamin D's potential to reduce the risk of hospital-acquired infections
• Acute respiratory distress – 100 percent of patients were vitamin D deficient
• Micronutrients (such as Vitamin D) for critically ill children – review
• Smokers should stop 1 month before surgery W.H.O.
• 8X more likely to have leaky gut in ICU if low vitamin D
• Plasma exchange cut vitamin D levels in half
• Hospitalization consumes vitamin D in children
• Critical illness – Vitamin D levels start low and then drop for several days
• Hospital Acquired Infection, Mortality, Critically Ill and Vitamin D - 2017
• Omega-3 reduced pancreas transplant failure by 3X and sepsis by 2X – review
• The effect of vitamin D on different human cells, with emphasis on burns and ICU
• Fewer Burn problems if adequate Vitamin D – Less ICU, Hospital, Sepsis (10X)
• Heart attack ICU costs cut in half by Vitamin D
• 3 additional hospital days after emergency neurosurgery if low vitamin D
• Stem cell transplant (HSCT) patients are dying due to lack of vitamin D
• Stem Cell Transplants consume vitamin D
• COPD ICU stay is 2.4 days longer if low vitamin D
• Hospitalization costs reduced ~3,000 dollars when intravenous nutrition was augmented with Omega-3
• Spinal Cord Injury treated by Vitamin D progesterone combination, etc. – review of trials
• 2X more likely to kill superbug in 1 month with adequate level of vitamin D
• MRSA inpatient cost 2X higher if less than 20 ng vitamin D
• Vitamin D being used by sports teams to avoid injuries and improve performance – WSJ
• Vitamin D and critical illness – many questions and unknowns (DBP etc)
• Foot and Ankle Surgeries should benefit from Vitamin D
• Vitamin B12 treats Traumatic Brain Injury in mice
• Vitamin D levels not associated with days in ICU (both short and long term residents had low vitamin D)
• Knee surgery reduced vitamin D by 40 percent in 2 days
• 1,000 IU of vitamin D daily did not help ICU much (no surprise)
• Congenital Heart problems - vitamin D levels drop even lower after surgery, loading dose probably required - thesis 2015
• Trauma with fracture – 2 weeks longer hospital stay if less than 10 ng vitamin D
• Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency and liver failure
• Brain injury disability associated with lower vitamin D
• Vitamin D appears essential to survive many critical illnesses - review
• Children entering ICU with low vitamin D were 3.5 X more likely to have a poor ICU score
• After hip surgery Vitamin D levels dropped by 32 percent
• Mild Traumatic Brain Injury reduced by Vitamin D
• Neurosurgical ICU patients critically low on Vitamin D
• Bed sores in ICU 2.5 X more likely if low vitamin D
• Virtually all Bariatric Surgery patients vitamin D deficient – should we routinely supplement
• Only 1600 IU of Vitamin D to be given following knee and hip replacement trial – 2020
• Better total hip replacement if have high vitamin D
• Dementia risk increased 2.4 X following TBI, even if had not lost consciousness
• Concussion which caused unconsciousness increased risk of Parkinson's by 50 percent (300,000 military)
• Heart Attack ICU costs reduced $37,000 by $20 of Vitamin D
• All ICU patients with good vitamin D level survived, none who died had a good level
• Fewer Complications Following Revision Hip and Knee Arthroplasty in Patients with Normal Vitamin D Levels
• 5 Traumatic brain injuries resulted in 2.8 X increased risk of dementia
• Critically ill dogs with good levels of vitamin D have much better outcomes (humans too)
• Deadly amount of vitamin D speeds up recovery of crushed muscles in rats
• Vitamin D is Way More Important in Critical Care Than We May Have Recognized
• Omega-3 benefits in surgery and ICU including via IV
• Vitamin D deficiency with severe sepsis increased risk of dying by 7.7 X
• Miraculous Vitamin D – recovered from coma in a week
• Including Vitamin D test results improved 90 day ICU mortality prediction (when will they add Vitamin D to patients)
• 2X more likely to get hospital infection if low vitamin D (10 ng) when enter
• ICU - lots of vitamin D in first week helped the dark skinned
• Magnesium may be an important way to treat brain trauma
• ICU patients with pneumonia stay 7 days longer if low vitamin D
• Sepsis was present in 6 percent of US adult hospitalizations – JAMA
• 20 percent of Critically ill in India had undetectable vitamin D, and 62 percent died
• Low Vitamin D when entering ICU is deadly (acute kidney injury in this case)
• Low vitamin D in Pediatric ICU – 5 times more ill (morbidity) – Spanish
• Twice as likely to die during neurological critical care if low vitamin D
• Having less than 15 ng of vitamin D increased risk of hospitalization with infection by 2.8 times
• Severe Sepsis associated with very low vitamin D
• Increased Hospital, Sepsis deaths if low vitamin D
• Fewest ICU deaths with lowest hCAP 18, but perhaps middle Vitamin D
• Children stayed in ICU 3.5 days longer if low vitamin D
• Half of Swiss emergency patients had low vitamin D: length of stay, mortality, etc.
• Vitamin D insufficiency increased after hip replacement: – 38% before, 68% the next day
• How to reduce hospital infections with vitamin D
• Higher vitamin D levels associated with fewer vein clots decades later
• Risk of death within 90 days of ICU decreased by 16 percent for 1 nanogram extra vitamin D
• 3X more likely to die within 3 months of being in ICU for 2 days if less than 20 ng vitamin D
• More sepsis deaths when active vitamin D (Calcitrol) was low
• Almost 6X more likely to die after coronary bypass if vitamin D deficient
• Acute Rehab. patients 2.3X more likely to have musculoskeletal pain if low vitamin D
• Chance of dying within 1 month of entering hospital is 45 percent higher if low vitamin D
• Cognitive decline after traumatic brain injury reduced by Omega-3 (mice)
• Prior to Bariatric Surgery 96 percent were vitamin D deficient
• Vitamin D Loading dose - 20,000 IU daily is not enough if obese, etc. (Cancer) great table and chart
• Increasing number of people admitted to a hospital in India have very high vitamin D
• Cardiac rehabilitation had more power if more than 20 nanograms of vitamin D
• 1 month after plasma exchange vitamin D levels reduced by 40 percent
• Sepsis associated with low vitamin D
• Radio frequency ablation survival doubled with even modest levels of vitamin D
• Staph infection reduced 50 percent when have more than 30 ng of vitamin D
• Infant in ICU much more likely to die if low vitamin D
• Omega-3 should be cost-effective to reduce days in ICU – simulation
• ICU time is 2X more likely to be longer than 2 days if vitamin D less than 20 ng
• ICU death 2X more likely if low vitamin D (sensitivity and selectivity chart)
• ICU patients with low Magnesium were 2X more likely to die
• ICU death 2X more likely if low Magnesium
• 5 days longer in ICU if low on vitamin D
• Longer mechanical ventilation times in ICU if lower vitamin D levels
• Vitamin D as a modifiable risk factor in critical illness - English and Portuguese
• 20 percent change in vitamin D levels of critically ill during a 24 hour period
• Inflammation or surgery or heart attack decreases measured vitamin D levels
• Fat soluable vitamins decrease quickly after trauma
• Critically ill patients with low vitamin D were 13X more likely to have a lot of mitrocondrial DNA in blood
• 96 percent vitamin D deficient – destitute asylum seekers and refugees in London
• Gut surgery appears to benefit from vitamin D
• When It Comes to Raising Vitamin D Levels, Anesthesiologists Advised—\"Don't Be Wimpy!\"
• 5 out of 6 children who died in pediatric critical care unit had low vitamin D
• Chance of death after non-cardiac surgery reduced 2X by Vitamin D
• More sepsis deaths in those entering hospital with low vitamin D
• One issue of Inflammation and Allergy-Drug Targets has vitamin D items behind paywall
• 540000 IU before ICU raised vitamin D by 25 ng in 2 days
• Hospital-Acquired Infections 3X more likely after Gastric Bypass if less than 30 ng vitamin D
• Stayed 3 days longer in geriatric acute care unit if low vitamin D – 2013
• Trauma – 86 percent had less than 30 ng of vitamin D, dark skinned even worse
• Hypomagnesemia (low Magnesium) is very prevalent in ICU – 1999
• Nursing home residents 2X more likely to die of some surgeries – perhaps lack vitamin D
• Vitamin D in the ICU: anything new under the sun
• Deep sedation in ICU reduced cognition even a year later (needed more vitamin D)
• Noticed bones heal faster when more than 60 ng of vitamin D
• ICU reduces Vitamin D levels, deregulates PTH
• Being vitamin D deficient in the ICU is not good
• ICU surgical patients with low vitamin D stayed longer and had more sepsis
• No association of cardiac surgery outcome with vitamin D level – they were all low
• HMOs will save millions of dollars with vitamin D
• Off topic: Use of ICU in month before death has increased to almost 30 pcnt
• Vitamin D deficiency after gastrointestinal surgery - 2009
• Critically ill 70 percent more likely to die if vitamin D less than 15ng
• Sepsis bacteria can be killed by blue as well as UV light
• Shorter time in ICU if have higher level of vitamin D
• Hip surgery followed by 100000 IU then 1000 IU of vitamin D daily
• Moderate and severe strokes 2X associated with low vitamin D – 2012
• Vitamin D supplementation did not decrease LDL lipids – Ha!
• Hardly any children had enough vitamin D before bone surgery
• Critical Care patients with less than 15 ng vitamin D were 85 percent more likely to die
• Highest vitamin D increases after spine surgery associated with best outcomes
• Every Thyroidectomy patient should get vitamin D and Calcium
• Stroke patients show dearth of vitamin D – 2005
• Vitamin D levels low both before and after organ transplant
• Septic shock and low vitamin D in children
• Critical Care patients need vitamin D
• Elderly surgical rehab in Germany - 67 pct have less than 10 ng vitamin D
• ICU needs vitamin D - Vitamin D Council
• Vitamin D levels of critically ill patients reduced 35 pct after blood dilution
• Virtually all veterans in ICU had vitamin D less than 32 ng
• Vitamin D reduces lung damage due to radiotherapy
• Survive surgery 3X better if overweight – Hypothesis - due to vitamin D released from fat
• Calcium and vitamin D supplements after hip fracture reduced death rate by 25%
• Should stock-up on vitamin D if having surgery due to fragile bones
• CV event 56 percent more likely after vascular surgery if low on vitamin D
• Patients low on vitamin D stay in hospital longer after thyroid removal
• Bypass surgery and vitamin D