4,000 IU of Vitamin D - many pages

111+ VitaminDWiki pages with 4,000 or 4000 in the title

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Items found: 114
Title Modified
Vitamin D is needed while pregnant - 200 IU to 4,000 IU daily (17 cliical guidelines) - Aug 2025 29 Sep, 2025
4,000 IU Vitamin D while pregnant does not decrease infant respiratory problems (no surprise) - meta-analysis July 2025 11 Jun, 2025
Lupus treated again by daily Vitamin D - 4,000 IU or 8,000 IU (slightly better) - RCT Feb 2025 14 Feb, 2025
Total Testosterone increased if take more than 4,000 IU vitamin D daily – meta-analysis Sept 2024 26 Sep, 2024
Prostate cancer risk reduced by Vitamin D (4000 IU daily) – June 2024 07 Aug, 2024
Vitamin d levels were restored from hemodialysis by 70,000 IU weekly total in 4 weeks - Feb 2024 25 Feb, 2024
4,000 IU of Vitamin D - many pages 19 Dec, 2023
4,000 IU of daily Vitamin D during pregnancy is good (Mongolia this time) – RCT Oct 2023 24 Oct, 2023
Just 4,000 IU of vitamin D was not enough to halt senior falls – July 2023 19 Jul, 2023
Respiratory infections reduced by 63 percent with 4000 IU vitamin D daily - RCT Dec 2012 17 Jul, 2023
Childhood and youth obesity – more than 4,000 IU vitamin D average daily would help – meta-analysis Jan 2023 12 Jan, 2023
Vitamin D daily - Evolution: 4,000 IU, Government: 800 IU– Veith Oct 2022 28 Oct, 2022
Yet another Vitamin D call-to-action (4000 IU) - Feb 2022 04 Oct, 2022
4X less likely to get COVID following 4,000 IU daily for a month – RCT April 2022 12 Jun, 2022
Risk of Frailty reduced 4X by 4,000 IU of vitamin D – RCT April 2022 10 Apr, 2022
Call for immediate action - Fight COVID-19 with vitamin D (up to 4,000 IU) - Jan 28, 2021 27 Feb, 2022
4,000 IU of Vitamin D is too small a dose to help Obese - RCT Feb 2022 09 Feb, 2022
Chronic Heart Failure reduced by 4,000 IU daily for a year – RCT April 2016 07 Oct, 2021
Minimum National Vitamin D recommendations range from 200 to 4,000 IU – July 2021 15 Jul, 2021
Vitamin D can improve bone health – 47 guidelines (range of 200 to 4000 IU daily) – May 2021 08 May, 2021
Consensus: Upper Limit of daily Vitamin D intake is still 4,000 IU (if you do not reduce Calcium) – Aug 2020 18 Dec, 2020
Evidence of Vitamin D fighting COVID-19 etc. - take 4,000 IU if less than 20 ng (UK) – Dec 1, 2020 06 Dec, 2020
4,000 IU of vitamin D for 1 month does not help (muscles in this case) – RCT Jan 2020 21 Sep, 2020
MRSA Carriers not helped by 4,000 IU of Vitamin D (probably poor Vitamin D Receptor) – RCT Sept 2018 14 Jul, 2019
Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019 10 Jul, 2019
After breast cancer treatment 4,000 IU of Vitamin D was not enough to help if have poor Vitamin D receptor – June 2019 04 Jun, 2019
4,000 IU of Vitamin D is OK - 19 organizations agree - 2018 19 May, 2019
Advanced Colorectal Cancer survival is increased somewhat with 4,000 IU of vitamin D – RCT April 2019 10 Apr, 2019
Periodontitis treated by 4,000 IU of Vitamin D (pilot study) - March 2019 27 Mar, 2019
Preeclampsia risk reduced 7X by 4,000 IU of Vitamin D daily – RCT March 2018 20 Feb, 2019
4,000 IU Vitamin D daily during pregnancy (Mongolia) was good – RCT Dec 2018 14 Dec, 2018
Sweden had banned selling more than 4,000 IU of vitamin D, Supreme Court canceled it – Dec 2018 03 Dec, 2018
1200 mg is too much Calcium for seniors if take 4,000 IU of vitamin D – Oct RCT 2018 16 Oct, 2018
Vitamin D during lactation – range from 4,000 IU daily to 150,000 IU monthly – Sept 2018 25 Sep, 2018
Migraine headaches cut in half by 4,000 IU of vitamin D – RCT Sept 2018 06 Sep, 2018
One-A-Day capsule with 4,000 IU of Vitamin D 14 Aug, 2018
Dementia – clinical trial using 4,000 IU of Vitamin D– 2023 02 Aug, 2018
Vitamin D - at least 4,000 IU to achieve 40-60 ng and reduce risk of early death – Holick June 2018 04 Jun, 2018
No genetic response to 4,000 IU of Vitamin D (other studies disagree) – RCT April 2018 15 Apr, 2018
Nordic Walking and 4,000 IU of vitamin D lowered cholesterol, fat, weight, and lipids (senior women) – RCT Feb 2018 09 Mar, 2018
Bone loss during black pregnancies – 4000 IU of vitamin D was not enough – Dec 2017 12 Dec, 2017
Prostate Cancer might be treated by 4,000 IU of vitamin D and aspirin – RCT 2021 28 Nov, 2017
Diabetes helped by daily 4,000 IU of Vitamin D – meta-analysis Sept 2017 02 Oct, 2017
Pregnancy needs at least 40 ng of vitamin D, achieved by at least 4,000 IU – Hollis Aug 2017 05 Sep, 2017
Palliative cancer benefit of 4,000 IU of Vitamin D – less opioids, infection, and CRP – Aug 2017 01 Sep, 2017
Obese helped with resistance training by 4000 IU of vitamin D – RCT Aug 2012 23 Aug, 2017
Beef was more tender and contained more vitamin D when finishing diet included 4,000 IU of Vitamin D – Dec 2017 03 Aug, 2017
4,000 IU of Vitamin D daily is safe, but takes a year to plateau (Best-D) – RCT Dec 2016 23 Jul, 2017
1,000 IU of Vitamin D while pregnant helped a little bit (4,000 IU helps a lot) – RCT Dec 2016 20 Jul, 2017
RTI – Feel much better if increase vitamin D level above 40 ng (4000 IU) – RCT Sept 2015 18 Jul, 2017
3 to 6 months to plateau with 4,000 IU vitamin D daily (Cardiac Patients) – June 2017 12 Jun, 2017
Pregnancy complications reduced with 4000 IU of vitamin D - 2RCT Jan 2013 21 Mar, 2017
Nasal polyposis greatly decreased by 4,000 IU of vitamin D for 4 weeks - 2014 12 Mar, 2017
Respiratory tract infection eliminated in 36 percent of people by 4000 IU of Vitamin D – RCT Sept 2015 13 Jan, 2017
Asthma in 3 year olds decreased somewhat with 4,000 IU during pregnancy – RCT Jan 2016 02 Dec, 2016
Leg bone (tibia) grew thicker with 4,000 IU of vitamin D and Calcium – RCT Aug 2016 19 Aug, 2016
4000 IU Vitamin D Safe and Effective For Healthy Pregnant Women – June 2011 23 May, 2016
Cognition of Alzheimer’s patients improved by daily 4,000 IU of vitamin D – RCT Jan 2015 16 Apr, 2016
Athletic performance and recovery benefits of Vitamin D (4000-5000 IU and Vitamin K) – Aug 2015 01 Mar, 2016
Asthma trial underway - 4,000 IU during pregnancy - March 2014 27 Jan, 2016
Battling the winter blues with vitamin D (4000 IU) Dec 2015 22 Dec, 2015
Low risk Prostate Cancer decreased with 4,000 IU of vitamin D – July 2012 21 Dec, 2015
4000 IU Vitamin D Safe and Effective For Healthy Pregnant Women – RCT June 2011 18 Dec, 2015
Musculoskeletal pain reduced with 4,000 IU of vitamin D – RCT April 2015 05 Nov, 2015
Optimal Vitamin D during pregnancy - 4000 IU March 2012 29 Sep, 2015
Hypertension reduction sometimes needs more than 4,000 IU of vitamin D for 6 months – RCT Oct 2014 22 Sep, 2015
4000 IU increased peak power in exercise vs placebo April 2010 27 Jul, 2015
Vitamin D measured in 4000 people for many years – longitudinal associations – May 2015 31 May, 2015
4,000 IU raised vitamin D levels during pregnancy – July 2014 06 May, 2015
Prostate cancer reduced when 4000 IU vitamin D was added– Hollis RCT April 2015 02 Apr, 2015
Seniors need at least 4,000 IU vitamin D, no test needed – Consensus Jan 2014 31 Mar, 2015
Need 4,000 IU vitamin D to prevent falls, no vitamin D test needed – Consensus Jan 2014 31 Mar, 2015
4000 IU vitamin D daily for just 5 days reduced inflammation after heart attack – RCT Jan 2013 16 Mar, 2015
Women taking 4,000 IU reduced pregnancy risks in half RCT May 2010 16 Mar, 2015
Adding 4,000 IU of vitamin D daily at 20 weeks pregnancy not help much – RCT March 2014 18 Feb, 2015
Is 4000 IU the best Vitamin D dose for seniors – RCT underway – Feb 2015 08 Feb, 2015
Muscle increased 17 percent in vitamin D insufficient elderly getting 4,000 IU for 4 months – RCT Oct 2013 27 Jan, 2015
Newborn Apgar score slightly higher if deficient mother had daily 4,000 IU vitamin D – RCT March 2014 06 Jan, 2015
Cancer – will 4,000 IU of vitamin D daily help in one month (no) – VIDAFACT Dec 2014 31 Dec, 2014
Best Vitamin D- 40 to 52 ng, achieved with 4000 – 6000 IU daily – Heaney Oct 2014 10 Nov, 2014
Infectious Disease typically not treated if use less than 4000 IU vitamin D daily– review Oct 2014 31 Oct, 2014
4000 IU RCT reduces type 2 diabetes HOMA by 24% and CRP by 64% April 2010 28 Oct, 2014
Diabetes prevention RCT kicked off: adding 4,000 IU vitamin D - Oct 2013 10 Sep, 2014
PSA levels in blacks were not changed by 3 months of 4,000 IU of vitamin D (not enough) – June 2014 02 Aug, 2014
Seniors with Heart Failure helped by daily 4,000 IU of vitamin D (increase 16 ng) – RCT Aug 2014 25 Jul, 2014
Forum discussions on Vitamin D - Treato 15,000 positive, 4,000 negative - July 2014 02 Jul, 2014
Little change in Calcium absorption when taking 400 vs 4,000 IU of vitamin D – Oct 2012 27 May, 2014
More Calcium absorbed with more vitamin D – 6.7% more with 4000 IU – RCT March 2014 27 May, 2014
Defining normal level of vitamin D (need 4000-5000 IU) - Heaney Spring 2013 26 May, 2014
Female healthcare employees: 4 percent took more than 4,000 IU vitamin D daily – May 2014 13 May, 2014
European adults can take 4000 IU of vitamin D – July 2012 13 May, 2014
4000 IU vitamin D daily reduced inflammation after heart attack – Review and RCT Jan 2013 05 Apr, 2014
Many healthy African Americans got above 33 ng with 4,000 IU of vitamin D – RCT March 2014 25 Dec, 2013
Inflammation in African Americans not reduced with 3 months of 4000 IU of vitamin D – RCT Dec 2013 25 Dec, 2013
Extra 4,000 IU daily raised the vitamin D levels of blacks to that of whites – July 2012 25 Dec, 2013
Calcium and 4,000 IU Vitamin D in Postmenopausal Women – RCT Nov 2013 06 Nov, 2013
Collegiate Swimmers getting 4000 IU of vitamin D had fewer injuries – March 2013 03 Nov, 2013
Pregnant women should have 4,000 IU of vitamin D – Topic review June 2013 04 Sep, 2013
Pregnancy needs 4000 IU of vitamin D: current opinion - June 2013 24 Jun, 2013
Insulin sensitivity in obese adolescents greatly improved with 4000 IU of vitamin D - RCT April 2013 20 Mar, 2013
Insulin improvement in obese teens with 4000 IU of vitamin D – RCT Feb 2013 11 Mar, 2013
Obese teens needed 4000 IU of vitamin D - Nov 2011 07 Nov, 2012
Fewer falls and fractures as vitamin D is increased – 1800 to 4000 IU July 2010 24 Jun, 2012
40 ng response plateau to 2000 to 4,000 IU of vitamin D – June 2012 19 Jun, 2012
Perhaps Stress fractures 2X less frequent if 4000 IU of vitamin D – June 2011 12 Jun, 2012
4000 IU vitamin D not enough to treat diabetes in overweight blacks in 3 months – May 2012 02 May, 2012
4000 IU vitamin D was not enough to reduce obesity – PhD 2010 21 Jul, 2011
Recommend 2500-4000 IU per day to reduce all-cause mortality by 18%– Grant Netherlands April 2010 13 Jul, 2011
4000 IU vitamin D and exercise for overweight – PhD 2010 02 Jul, 2011
4000 IU vitamin D improved glycemic control for type 1 diabetes – Nov 2010 11 Nov, 2010
4000 IU Vitamin D intervention helped elderly bones – March 2010 16 Oct, 2010
2500 to 4000 IU vitamin D would decrease specific disease rates- April 2010 31 Aug, 2010
4000 IU vitamin D3 improves insulin resistance – Feb 2010 01 Aug, 2010
Migraine headaches associated with low vitamin D, 4,000 IU often helps – review Aug 2019 No value for 'modification_date_major'

4000 IU daily - rare risk of hypercalcemia - meta-analysis Feb 2023 (can reduce risk by subtracting Calcium or adding Vitamin K2)

Long-term supplementation with 3200 to 4000 IU of vitamin D daily and adverse events: a systematic review and meta-analysis of randomized controlled trials
European Journal of Nutrition February 2023
Armin Zittermann, Christian Trummer, Verena Theiler-Schwetz & Stefan Pilz

Note: No indication of how much Calcium (food or supplement) each group was taking
Nor if any vitamin K2 was taken (which reduces Calcium in the blood)

Image
Purpose
The upper tolerable intake level for vitamin D in the general population has been set at 4000 international units (IU) daily, but considerable uncertainty remains. We summarized the reported harmful effects of a daily vitamin D supplement of 3200–4000 IU in trials lasting ≥ 6 months.

Methods
We performed a systematic review and meta-analysis of randomized controlled trials in several databases and identified 22 trials reporting safety data. Parameters of calcium metabolism, falls, hospitalization, and mortality were assessed.

Results
The selected trials comprised a total number of 12,952 participants. All trials used supplemental vitamin D3. The relative risk (RR) of hypercalcemia in the vitamin D vs. control arm was 2.21 (95%CI: 1.26–3.87; 10 studies), with a vitamin D-induced frequency of hypercalcemia of 4 cases per 1000 individuals. Subgroup analysis in trials with > 100 and ≤ 100 study participants revealed an RR of 2.63 (95%CI: 1.30–5.30; 7 studies) and 0.80 (95%CI: 0.24–2.62; 3 studies), respectively (Pinteraction = 0.06). Risks of falls and hospitalization were also significantly increased in the vitamin D arm with an RR of 1.25 (95%CI: 1.01–1.55; 4 studies) and 1.16 (95%CI: 1.01–1.33; 7 studies), respectively. Risks of hypercalciuria, kidney stones, and mortality did not differ significantly between study arms. The quality assessment revealed a high risk of incomplete reporting of safety-related outcome data.

Conclusion
Supplemental vitamin D doses of 3200–4000 IU/d appear to increase the risk of hypercalcemia and some other adverse events in a small proportion of individuals, indicating that this dose is not completely safe. In future studies, rigorous reporting of safety-related outcomes is needed when using moderately high doses of vitamin D.
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VitaminDWiki – Consensus Vitamin D category contains:

77 Vitamin D consensus publications

Charts from Overview Vitamin D Dose-Response 4,000 IU ==> 36 or 55 ng

Dose Response Dec 2015 (VDW# 7156)

GARLAND. FRENCH . BAGGERLY. HEANEY

Response - 8 studies bit.ly/16TuWp5

See also VitaminDWiki

Is 50 ng of vitamin D too high, just right, or not enough

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