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Vitamin D can improve bone health – 47 guidelines (range of 200 to 4000 IU daily) – May 2021

Methodological quality of recommendations on vitamin D and calcium – a systematic review of bone health guidelines

Preprint doi: https://doi.org/10.1101/2021.05.01.21256288
Zhaoli Dai, Joanne E McKenzie, Sally McDonald, Liora Baram, Matthew J Page, Margaret Allman-Farinelli, David Raubenheimer, Lisa A. Bero

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VitaminDWiki

Bone - Health category starts with the following

283 items in Bone - Health category
See also

Calcium and Vitamin D category has the following summary

Calcium often causes major health problems

  • Many studies have identified many health problems with Calcium supplementation
  • < 750 mg of Calcium supplement daily - VitaminDWiki has recommended for 7 years
  • Some believe that the health problems are due to the spike in blood Calcium from taking the Calcium only once per day - [https://nutritionfacts.org/2018/03/22/if-calcium-supplements-arCalciumen't-safe-what-about-calcium-in-food/?utm_source=NutritionFacts.org&utm_campaign=09083c9570-RSS_BLOG_WEEKLY&utm_medium=email&utm_term=0_40f9e497d1-09083c9570-25209481&mc_cid=09083c9570&mc_eid=b95641625a|Dr. Greger - March 2018 text and short video]
  • Perhaps there would be a shorter Calcium spike (and less of a problem) if take Calcium multiple times a day
  • Perhaps also less of a problem if the source of supplement ifs plant-based
  • [https://nutritionfacts.org/video/are-calcium-supplements-safe/|Calcium from milk also causes 5+ major health problems] 2015
    • No apparent health problems from processed dairy products (cheese, yogurt, etc)
  • Calcium supplements are less of a problem if have adequate Vitamin K
    • which keeps Calcium from forming blood-system plaque
  • [http://gut.bmj.com/content/early/2018/01/29/gutjnl-2017-315242 |2.7X increase in rate of Colon polyps in 6-10 years] RCT March 2018
  • Calcium from food or supplements associated with more deaths (US Cohort of 31,000 people) – April 2019

see wikipagehttp://www.vitamindwiki.com/tiki-index.php?page_id=1936

released Nov 30, 2010

 Download the preprint from VitaminDWiki

There are numerous guidelines developed for bone health. Yet it is unclear the differences in guideline development methods explain the variability in recommendations for vitamin D and calcium intakes. The objective of this systematic review was to collate and compare recommendations for vitamin D and calcium across bone health guidelines, assess methods used to form the recommendations, and explore which methodological factors were associated with these guideline recommendations. We searched MEDLINE, EMBASE, CINAHL and other databases indexing guidelines to identify records in English between 2009 and 2019. Guidelines or policy statements on bone health or osteoporosis prevention for generally healthy adults aged ≥40 years were eligible for inclusion. Two reviewers independently extracted recommendations on daily vitamin D and calcium intake, supplement use, serum 25 hydroxy vitamin D [25(OH)D] level, and sunlight exposure; assessed guideline development methods against 25 recommended criteria in the World Health Organization (WHO) Handbook for Guideline Development; and, identified types of evidence underpinning the recommendations.

We included 47 eligible guidelines from 733 records:

  • 74% of the guidelines provided vitamin D (200∼600-4000 IU/day) and
  • 70% provided calcium (600-1200 mg/day) recommendations;
  • 96% and 88% recommended vitamin D and calcium supplements, respectively; and
  • 70% recommended a specific 25(OH)D concentration.

The mean of meeting 25 WHO methodological criteria per guideline was 10 (95% CI: 9-12; interquartile range: 6-15). There was uncertainty in the associations between the methodological criteria and the proportion of guidelines that provided recommendations on daily vitamin D or calcium. Various types of evidence, ranging from previous bone guidelines, nutrient reference reports, systematic reviews, observational studies, to perspectives/editorials were used to underpin the recommendations. In conclusion, there is considerable variability in vitamin D and calcium recommendation and in guideline development methods in bone health guidelines. Effort is required to strengthen methodological rigor of guideline development and utilize the best available evidence to underpin public health nutrition.


Created by admin. Last Modification: Saturday May 8, 2021 13:32:28 GMT-0000 by admin. (Version 8)

Attached files

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15568 Bone Vit D.jpg admin 08 May, 2021 13:12 103.54 Kb 82
15567 Many guidelines for bone and vitamin D.pdf PDF 2021 admin 08 May, 2021 13:11 760.07 Kb 22
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