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Cognition of Alzheimer’s patients improved by daily 4,000 IU of vitamin D – RCT Jan 2015

Role of Vitamin-D in the prevention and treatment of Alzheimer's disease.

Indian J Physiol Pharmacol. 2015 Jan-Mar;59(1):94-9.
Gangwar AK, Rawat A, Tiwari S, Tiwari SC, Narayan J, Tiwari S.

Changes in MMSE Scores from PDF (subset of the table)

Vitamin D
(4,000 IU daily)
Placebo
3 month to 6 month 2.37±1.33 1.72±1.30

MMSE = Mini Mental State Examination
Lower MMSE = poorer cognition

VitaminDWiki

Alzheimers-Cognition - Overview has the following summary


Items in categories Cognition and Intervention (give Vitamin D and see what happens)

 Download the PDF from VitaminDWiki

Alzheimer's disease is the most common form of age related cognitive impairment. Aim of the present study was to see the effect of vitamin D on cognitive function in elderly. The study was conducted in Department of Physiology, King George's Medical University (KGMU). A total of 80 subjects were enrolled based on Mini Mental State Examination (MMSE) score < 24 and vitamin D deficiency. They were divided into two groups as Group A (case) and Group B (control), each group having 40 subjects. Intervention (Vitamin D supplementation) was given in Group A. The assessment of dementia was done by Mini Mental State Examination (MMSE) score. Every subject was clinically evaluated and estimation of vitamin D was done by direct ELISA kit. Gender, weight, height, BMI, residence and education were also similar between two groups. A significant (p=0.0001) change in MMSE score was observed in both Group A and Group B from baseline to 3 & 6 months and from 3 to 6 months, however, mean change was higher in Group A than Group B.
In conclusion, vitamin D supplementation caused significant improvement in the cognitive performance in subjects with senile dementia.
PMID: 26571990

Attached files

ID Name Comment Uploaded Size Downloads
6566 Role of D with Alz.pdf PDF 2015 admin 16 Apr, 2016 20:31 43.00 Kb 237
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