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Overview Cancer and vitamin D


Scores of studies show that Vitamin D prevents many cancers and treats a few cancers

  • Prevention results from 2,000 to 5,000 IU of vitamin D
    Prevention really depends on the level of vitamin D in the blood, and some vitamin D-deficient groups need much more
  • Treatment needs > 8,000 IU of vitamin D
    But must be careful, as vitamin D makes some Chemotherapy more potent

A high percentage of all cancer deaths are prevented by a high enough level of vitamin D in your bloodstream

derived from Grassroots 2013


VitaminDWiki – Cancer category contains


Cancers get less Vitamin D when there is a poor Vitamin D Receptor


VitaminDWiki - 87+ VDR pages have CANCER in the title


Vitamin D fights cancer in many ways - GrassrootsHealth Sept 2022

How Vitamin D Works to Help Prevent Cancer

  • Inhibits cancer cell growth and proliferation
  • Reduces cancer metastasis
  • Stimulates maturation of healthy cells (differentiation)
  • Induces death of cancer cells (apoptosis or programmed cell death)
  • Prevents blood vessel growth in tumors (angiogenesis)
  • Prevents inflammation associated with cancer
  • Reduces the risk of incidence and/or death due to cancer

See also (VitaminDWiki)

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Vitamin D and cancer clinical trials: 23 in VitaminDWiki, 453 in Clinical Trials.gov

Intervention pages with CANCER in the title
This list is automatically updated

Items found: 31
Title Modified
Breast Cancer survival: 44% with just 10,000 IU of vitamin D per week, 33% with placebo – RCT Dec 2023 13 Aug, 2023
Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding) 18 Apr, 2023
After Colorectal Cancer Surgery the immune system was maintained by Vitamin D (8,000 IU daily) – RCT Jan 2023 03 Jan, 2023
Cancer risk reduced 65 percent by vitamin D levels greater than 40 nanograms – April 2016 31 Dec, 2022
2.5 X reduced risk of cancer in 70 year-olds by a small amount of Vitamin D, Omega-3 and exercise – RCT April 2022 25 Apr, 2022
Breast Cancer not prevented by 1,000 IU of Vitamin D (no surprise) – RCT Aug 2021 14 Apr, 2022
Rectal Cancer genes down-regulated by Vitamin D (3,200 IU only helped some) – RCT Aug 2021 03 Aug, 2021
Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT Sept 2019 25 Jul, 2021
Digestive Tract Cancer survival increased 3X if 2,000 IU of vitamin D and have high level of PD-L1 – RCT June 2021 29 Jun, 2021
Prostate Cancer PSA reduced by 60 ng of Vitamin D, Vitamin B complex, Omega-3, Curcumin and diet – June 2021 20 Jun, 2021
2,000 IU of vitamin D and Omega-3 reduced Cancer death rate bv 40% (normal weight) – VITAL RCT Nov 2020 03 Dec, 2020
Breast Cancer chemo reduces Bone Mineral Density, injecting Vitamin D increases it – Sept 2019 07 Sep, 2019
Multiple Myeloma (blood cell cancer) treated by vitamin D - many studies 14 Jun, 2019
After breast cancer treatment 4,000 IU of Vitamin D was not enough to help if have poor Vitamin D receptor – June 2019 04 Jun, 2019
Digestive tract cancer death rates reduced a bit by a bit of vitamin D – RCT April 2019 10 Apr, 2019
Advanced Colorectal Cancer survival is increased somewhat with 4,000 IU of vitamin D – RCT April 2019 10 Apr, 2019
Vitamin D and Omega-3 Ineffective for Preventing Cancer and Heart Disease (too little was used) – Nov 2018 21 Nov, 2018
Lung cancer treated by Vitamin D (1200 IU early stage) – RCT July 2018 04 Sep, 2018
Liver cancer nicely treated by high dose vitamin D for 16 weeks (early stage, in rats) – April 2018 23 Apr, 2018
Prostate Cancer might be treated by 4,000 IU of vitamin D and aspirin – RCT 2021 28 Nov, 2017
Lymphoid cancer deaths cut in half with 400 IU of vitamin D and 1 gram of Calcium (WHI) – RCT Nov 2017 04 Nov, 2017
Prostate Cancer treatment (Vitamin D, Omega-3, Tumeric) RCT ending Dec 2018 26 Sep, 2017
Palliative cancer benefit of 4,000 IU of Vitamin D – less opioids, infection, and CRP – Aug 2017 01 Sep, 2017
Low risk Prostate Cancer decreased with 4,000 IU of vitamin D – July 2012 21 Dec, 2015
Colon Cancer proven again to not be treated by just 1000 IU of vitamin D – RCT Oct 2015 20 Oct, 2015
Breast Cancer medicine pain reduced with 4300 IU vitamin D – RCT June 2012 24 May, 2015
Prostate cancer reduced when 4000 IU vitamin D was added– Hollis RCT April 2015 02 Apr, 2015
Active form of vitamin D appears to help prevent and treat some cancers – Feb 2011 16 Mar, 2015
Not enough women willing to stop taking vitamin D to permit breast cancer clinical trial – June 2012 14 Mar, 2015
Breast Cancer reduced 20 percent by just 400 IU of vitamin D plus Calcium – 2011 15 Nov, 2014
Mayo clinic starting Cancer RCT using grossly inadequate 2,000 IU of vitamin D – Sept 2013 04 Dec, 2013

Cancer Intervention Trials with Vitamin D 452 of Sept 2022


55% Cancer increase in young adults in 30 years in middle-income countries - 2023

The unexplained rise of cancer among millennials
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They suspect the increase is due to Ultra-processed food ==> poor gut biome
VitaminDWiki additionally suspects herbicides & pesticides ==> poor gut biome


VitaminDWiki - 10 Infant-Child pages with CANCER in the title

This list is automatically updated

Items found: 15

253 Cancer – Breast items

which includes


141 Cancer – Colon items

which includes


101 Cancer - Prostate items

which includes


56 Cancer - Pancreatic items

which include


55 Cancer – Lung items

which includes


112 Cancer – After items

which includes


121 Cancer – Skin items

which includes


25 Cancer – Lymphoma items

which includes


290 Cancer – General items

which includes


Following graph from the CDC August 2010

from PDF in File Gallery - More about vitamin D, also wiki
CLICK HERE for Original study by Lappe - 2007
41 minutes good video of Lappe explaining the trial
in which she mentions the next 5-year trial underway with 2,000 IU of vitamin D
Breast Cancer details from the study
For years 2-4
Placebo: 8 Breast Cancers out of 266 women
1100 IU vitamin D + Calcium 4 Breast Cancers out of 403 women
That is 8/266 ==> 4/403 with vitamin D
So roughly 3% ==> 1% with 1100 IU of vitamin D
about a 3X reduction for Breast Cancer(vs 4X reduction for all Cancers)
CLICK HERE for Lappe -2011 slide description of the original study
See wikipage:http://www.vitamindwiki.com/tiki-index.php?page_id=931


Colon Cancer Chart: Vitamin D > 40ng is good

BISCHOFF April-2010  PDF


Increase in Childhood Cancer in recent decades

Childhood Cancer Increase


Cancer $creening Doesn't Save Lives, 2 Meta-Analyses 2015, 2023

Cancer $creening Doesn't Save Lives, Meta-Study Reveals
The huge problem of false positives/overdiagnosis GreenMedInfo Jan 2015

  • Estimated Lifetime Gained With Cancer Screening Tests: A Meta-Analysis of Randomized Clinical Trials - Sept 2015 - doi: 10.1001/jamainternmed.2023.3798
    • "Conclusions and relevance: The findings of this meta-analysis suggest that current evidence does not substantiate the claim that common cancer screening tests save lives by extending lifetime, except possibly for colorectal cancer screening with sigmoidoscopy."
    • Can be read at DeepDyve

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The Impact of Vitamin D in Cancer - book chapter - 2017

 Download the PDF from VitaminDWiki


Alternative therapies have worse outcomes when cancer therapy is ignored - July 2018

Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers
Skyler B. Johnson, MD1; Henry S. Park, MD, MPH1; Cary P. Gross, MD2; et al James B. Yu, MD, MHS1,2
JAMA Oncol. Published online July 19, 2018. doi:10.1001/jamaoncol.2018.2487
 Download the PDF from VitaminDWiki
"Vitamin D" does not occur once in the study
Note: The study only looks at
Cancer treatment, not prevention
Cancer mortality, not cancer survival


Cancer Factoids from The Body, by Bill Bryson, 2019

  • They (Cancers) have evolved to avoid detection,” says Vormoor. “They can hide from drugs. They can develop resistance. (VitaminDWiki also believes that many have also learned to hide.
  • Something we have only recently realized is that before cancers metastasize, they are able to prepare the ground for an invasion in distant target organs, probably through some form of chemical signaling. “What this means,” Vormoor says, “is that when cancer cells spread to other organs, they don’t just turn up and hope for the best. They already have a base camp.
  • Viruses and bacteria cause cancers, too. The World Health Organization 2011 estimated that 6 percent of cancers in the developed world but 22 percent in low- and middle-income countries are attributable to viruses alone.
  • A significant fraction of childhood cancer deaths come not from the cancer itself but from the treatments for it.

Aloe appears to help with Cancer chemo and radiation therapy - Greger - July 2022

Aloe Is Put to the Test Against Cancer
Also mentions Aloe treating eye cancer in an individual - without any surgery or other treatment.
Note: The wife of the founder of VitaminDWiki used several aloe plants to treat her Breast Cancer radiation therapy burns about 20 years ago.


Cancer Incidence in Men and Women, and Vitamin D ( 2022)

CancerMenWomen Vitamin D
Bladder 1 in 26 1 in 86D
Colorectal 1 in 24 1 in 25D
Lung 1 in 16 1 in 17 D
Melanoma 1 in 27 1 in 40D
Pancreatic 1 in 49 1 in 61D
Prostate 1 in 8 -D
Breast- 1 in 8D
Uterine- 1 in 32
Thyroid? 1 in 55 D
Ovarian - 1 in 85D

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Overview Cancer and vitamin D        
124171 visitors, last modified 04 Jul, 2024,
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Attached files

ID Name Comment Uploaded Size Downloads
20077 Cancer Screening.jpg admin 07 Sep, 2023 21.17 Kb 535
19676 Cancer rates vs income.jpg admin 20 Jun, 2023 26.87 Kb 698
19674 Increase cancer ty type.jpg admin 20 Jun, 2023 56.07 Kb 701
19673 Cancer - young - overall rate.jpg admin 20 Jun, 2023 54.70 Kb 707
18444 Cancer GRH.jpg admin 19 Sep, 2022 178.41 Kb 1521
10235 jamaoncology_Johnson_2018_oi_180051.pdf admin 23 Jul, 2018 225.37 Kb 2425
7879 Cancer Chapter - 2017.pdf admin 25 Mar, 2017 461.98 Kb 1702