- Only Vitamin D was found to treat post-partum depression - Meta-analysis April 2023
- VitaminDWiki -
21 studies in both categories Pregnancy and Depression - Omega-3 typically fights postpartum depression (ignores Omega-6) Jan 2024
- See Omega-6 blocks Omega-3 etc. -many studies
- FDA announced fast-acting Zurzuvae pill for postpartum depression - Aug 2023
- To be fast acting, Vitamin D needs to start with a loading dose (otherwise it takes many months)
- There have been
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Only Vitamin D was found to treat post-partum depression - Meta-analysis April 2023
Dietary interventions for perinatal depression and anxiety: a systematic review and meta-analysis of randomized controlled trials
Am J Clin Nutr. 2023 Apr 3;S0002-9165(23)46315-0. doi: 10.1016/j.ajcnut.2023.03.025 PDF is behind a paywall
Zoe Tsai 1, Nirmay Shah 2, Umair Tahir 2, Neda Mortaji 3, Sawayra Owais 4, Maude Perreault 5, Ryan J Van Lieshout 3Background: Dietary interventions are a widely available intervention for depression and anxiety among pregnant and/or postpartum (i.e., perinatal) persons but their effectiveness is not well known.
Objective: We performed a systematic review and meta-analysis to assess the effectiveness of dietary interventions for the treatment of perinatal depression and/or anxiety.
Design: We searched Medline, EMBASE, PsycINFO, CINAHL, and Web of Science from their inception to November 2, 2022. Studies were included if they were available in English and examined the effectiveness of a dietary intervention for perinatal depression and/or anxiety in a randomized controlled trial.
Results: Our search identified 4,246 articles, 36 of which were included and 28 were eligible for meta-analysis. Random effects meta-analyses were performed.
- Polyunsaturated fatty acids (PUFAs) were not found to improve symptoms of perinatal depression compared to control conditions (SMD -0.11; 95% CI -0.26 to 0.04). These results did not change when examined during pregnancy or the postpartum period separately, nor did they vary according to fatty acid ratio.
- Elemental metals (iron, zinc, and magnesium) were also not found to be superior to placebo (SMD, -0.42; 95% CI, -1.05 to 0.21), though,
- vitamin D yielded a small to medium effect size improvements (SMD, -0.52; 95% CI, -0.84 to -0.20) in postpartum depression.
- Iron may help in those with confirmed iron deficiency. Narrative synthesis was performed for studies ineligible for meta-analyses.
Conclusions: Despite their widespread popularity, PUFAs and elemental metals do not appear to effectively reduce perinatal depression. Vitamin D taken in doses of 1800 to 3500 International Units (IU) per day may have some promise. Additional high-quality, large-scale randomized controlled trials (RCTs) are needed to determine the true effectiveness of dietary interventions on perinatal depression and/or anxiety.
VitaminDWiki -
21 studies in both categories Pregnancy and Depression This list is automatically updated
- Post-partum depression and low Vitamin D - many studies
- Postpartum depression 3.6 X higher risk if low vitamin D – Jan 2022
- ADHD 3.7 X higher risk if depressed pregnancy (low vitamin D) – Dec 2020
- Depression after childbirth 5 X less likely if good Omega-3 index – April 2019
- Postpartum Depression 3.3 X more likely if low vitamin D – Oct 2018
- Vitamin D prevents pregnancy depression (US Prevention Task Force say it cannot be prevented) - Feb 2019
- Depressed black pregnant women should take vitamin D – April 2018
- Magnesium in Healthcare (Rickets, Stones, Pregnancy, Depression, etc.) with level of evidence – Sept 2017
- Perinatal depression decreased 40 percent with just a few weeks of 2,000 IU of vitamin D – RCT Aug 2016
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- Depression in youths associated with low vitamin D during pregnancy – Oct 2014
- Postpartum depression 7X more likely if less than 10 ng of vitamin D – Sept 2014
- Depression after pregnancy and vitamin D – Nov 2013
- Depression and Vitamin D during Pregnancy – Dissertation Aug 2014
- Depression during pregnancy twice as likely if consume little vitamin D – July 2014
- Antidepressants might increase infertility and pregnancy problems – Nov 2012
- Association between season of birth and suicide – perhaps vitamin D – Sept 2012
- Depression 50 percent more likely if low vitamin D in early pregnancy – Aug 2012
- Pregnant blacks 50 pcnt more likely to be depressed if 3 ng less vitamin D – July 2012
- Depressed mothers more likely to have small babies – Aug 2010
- An Exploratory Study of Postpartum Depression and Vitamin D - May 2010
Omega-3 typically fights postpartum depression (ignores Omega-6) Jan 2024
A Critical Look at Omega-3 Supplementation: A Thematic Review
Healthcare 2023,11, 3065. https://doi.org/10.3390/ healthcare11233065
Yamil Liscano yamil.liscano00 at usc.edu.co 1 0 and Natalia Sanchez-Palacio 2
Grupo de Investigación en Salud Integral (GISI), Departamento Facultad de Salud, Universidad Santiago de Cali, Cali 5183000, Colombia
Grupo de Investigación en Promoción de la Salud y Prevención de la Enfermedad, Universidad de Caldas, Manizales 170004, Colombia; natalia.sanchez at ucaldas.edu.coPostpartum depression (PPD) affects 10-20% of women. Traditional treatments have raised concerns, but omega-3 fatty acids show potential as an alternative. This thematic review, sourced from databases like PubMed and Scopus between 1 February 2023 and 15 March 2023, seeks to delve into the various perspectives on omega-3 supplementation for PPD. The criteria included studies detailing depressive symptoms, social functioning, and neurobiological variables. The review includes research with women showing PPD symptoms, randomized clinical trials, and articles in Spanish, English, and French. Exclusions were studies lacking proper control comparisons and other interventions besides omega-3. Data extraction was performed independently. Two key studies provide contrasting findings on omega-3's impact on PPD symptoms. In the study comparing DHA supplementation to a placebo, significant differences were not found in the EPDS scale, but differences were observed in the BDI scale. In contrast, another study recorded a significant decrease in depression scores in all dose groups, with reductions of 51.5% in the EPDS scale and 48.8% in the HRSD scale. Other studies, encompassing both prenatal and postpartum periods, underscore the differentiation between prenatal depression and PPD. Despite shared diagnostic criteria, PPD presents unique symptoms like restlessness, emotional lability, and baby-related concerns. It is crucial to address biases and obtain specific results, recommending exclusive PPD-focused studies. This review emphasizes the need for continuous exploration of omega-3's relationship with PPD to enhance the life quality of pregnant women and their families.
Download the PDF from VitaminDWiki
See Omega-6 blocks Omega-3 etc. -many studies
FDA announced fast-acting Zurzuvae pill for postpartum depression - Aug 2023
- "The FDA warned that the drug’s side effects can include drowsiness, dizziness, fatigue, diarrhea, urinary tract infection and nasopharyngitis (the common cold)."
- A persion "cautioned that Zurzuvae is not a “magic pill” for broadly solving postpartum depression."
To be fast acting, Vitamin D needs to start with a loading dose (otherwise it takes many months)
Millions of people have all successfully use Vitamin D loading doses.
There are an extremely wide variety of loading dose protocols, all of which work
50,000 IU of vitamin D daily for a week is one example
Hundreds of studies are compared at Overview Loading of vitamin D
There have been
203917 visits to this page
Post-partum depression and low Vitamin D - many studies(Cached) Printer Friendly Follow this page for updates181106 visitors, last modified 03 Apr, 2024, This page is in the following categories (# of items in each category)