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Multiple COVID vaccinations might increase Cancer Incidence - many studies

SARS-CoV-2 Vaccination and the Multi-Hit Hypothesis of Oncogenesis - Dec 2023

Cureus 15(12): e50703. doi:10.7759/cureus.50703
Raquel Valdes Angues • Yolanda Perea Bustos

Cancer is a complex and dynamic disease. The “hallmarks of cancer” were proposed by Hanahan and Weinberg (2000) as a group of biological competencies that human cells attain as they progress from normalcy to neoplastic transformation. These competencies include self-sufficiency in proliferative signaling, insensitivity to growth-suppressive signals and immune surveillance, the ability to evade cell death, enabling replicative immortality, reprogramming energy metabolism, inducing angiogenesis, and activating tissue invasion and metastasis. Underlying these competencies are genome instability, which expedites their acquisition, and inflammation, which fosters their function(s). Additionally, cancer exhibits another dimension of complexity: a heterogeneous repertoire of infiltrating and resident host cells, secreted factors, and extracellular matrix, known as the tumor microenvironment, that through a dynamic and reciprocal relationship with cancer cells supports immortality, local invasion, and metastatic dissemination. This staggering intricacy calls for caution when advising all people with cancer (or a previous history of cancer) to receive the COVID-19 primary vaccine series plus additional booster doses. Moreover, because these patients were not included in the pivotal clinical trials, considerable uncertainty remains regarding vaccine efficacy, safety, and the risk of interactions with anticancer therapies, which could reduce the value and innocuity of either medical treatment.

After reviewing the available literature, we are particularly concerned that certain COVID-19 vaccines may generate a pro-tumorigenic milieu (i.e., a specific environment that could lead to neoplastic transformation) that predisposes some (stable) oncologic patients and survivors to cancer progression, recurrence, and/or metastasis.

This hypothesis is based on biological plausibility and fulfillment of the multi-hit hypothesis of oncogenesis (i.e., induction of lymphopenia and inflammation, downregulation of angiotensin-converting enzyme 2 (ACE2) expression, activation of oncogenic cascades, sequestration of tumor suppressor proteins, dysregulation of the RNA-G quadruplex-protein binding system, alteration of type I interferon responses, unsilencing of retrotransposable elements, etc.) together with growing evidence and safety reports filed to Vaccine Adverse Effects Report System (VAERS) suggesting that some cancer patients experienced disease exacerbation or recurrence following COVID-19 vaccination.

In light of the above and because some of these concerns (i.e., alteration of oncogenic pathways, promotion of inflammatory cascades, and dysregulation of the renin-angiotensin system) also apply to cancer patients infected with SARS-CoV-2, we encourage the scientific and medical community to urgently evaluate the impact of both COVID-19 and COVID-19 vaccination on cancer biology and tumor registries, adjusting public health recommendations accordingly.
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Multi-Hit Hypothesis for the Oncogenic Potential of mRNA COVID-19 Vaccines - Sept 2023

Pathophysiologic Support for the Observation of "Turbo Cancer" after Vaccination
Dr. McCullough - Substack

  • "In 1984, Sutherland and Bailer proposed the “Multi-Hit Hypothesis of Carcinogenesis:”"
  • "They essentially said it takes multiple different hits or insults to cells and their genetic machinery to cause a normal cell to become cancerous."
  • " As we point out in our book Courage to Face COVID-19, it took over 40 years from when Sir Austin Bradford Hill causally associated smoking with lung cancer until there was capitulation by the medical orthodoxy."

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Cancers Appearing in Ways Never Before Seen After COVID Vaccinations: Dr. Harvey Rischn- Sept 2023

Epoch Times

  • “Some of these cancers are so aggressive that between the time that they're first seen and when they come back for treatment after a few weeks, they've grown dramatically compared to what oncologists would have expected for the way cancer normally progresses,”

16+ VitaminDWiki Virus pages with CANCER in title

This list is automatically updated

Items found: 16
Title Modified
Cancers take years to develop, but already have 36 COVID vaccination suspected cancers - May 2024 21 May, 2024
Increased cancer rate after 3rd vaccination (Japan in this study) - April 2024 11 Apr, 2024
Benign Cancers of a portion of the brain increased 1.8 X after vaccines were available - March 2024 24 Mar, 2024
Multiple COVID vaccinations might increase Cancer Incidence - many studies 24 Mar, 2024
Benign Cancers of a portion of the brain increased 1.8 X after vaccines were available - March 2024 24 Mar, 2024
Vitamin D: Viral infections, Infectious diseases, EBV and MS, Virus and Cancers – Grant March 2024 03 Mar, 2024
50% increase in Cancer deaths (age 15-44) since before COVID - Nov 2023 21 Nov, 2023
Cancers are associated with low vitamin D, poor vaccination response and perhaps poor VDR – July 2022 15 Aug, 2022
COVID, Cancer, etc. are Vitamin D low-hanging-fruit – Editorial June 2022 07 Jul, 2022
Breast Cancer risk factor is a virus in dairy products - March 2022 07 Mar, 2022
Hypothesis: Smoking reduces Vitamin D, which activates EBV, which causes lung cancer – Jan 2022 04 Mar, 2022
Vitamin D probably has a Role in Cancer, CVD, and COVID - video and transcript Dec 1, 2021 02 Dec, 2021
Virus cause some cancers 28 Aug, 2021
‘Long haul’ COVID rehab worse than cancer rehab, CDC – July 2021 13 Jul, 2021
Those with recent cancer diagnosis had 7X increased risk of COVID-19 (more if A-A )- Dec 2020 19 Feb, 2021
Adaptive immunity (cancer, viruses, autoimmune) and vitamin D – April 2016 25 Apr, 2016

50% increase in Cancer deaths (age 15-44) since before COVID - Nov 2023

Cancer after vaccines - Dalgleish & Campbell video Oct 2023

YouTube 76 minutes

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Attached files

ID Name Comment Uploaded Size Downloads
20492 Multi-hit chart.png admin 20 Dec, 2023 150.50 Kb 164
20491 Multi-Hit Hypothesis of Oncogenesis.pdf admin 20 Dec, 2023 703.10 Kb 77
20153 COVID Cancer_CompressPdf.pdf admin 30 Sep, 2023 543.24 Kb 122
20152 Sutherl 1984_CompressPdf.pdf admin 30 Sep, 2023 736.99 Kb 108