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PMS in teens reduced 3X by 50,000 IU vitamin D weekly – Jan 2018

High dose vitamin D supplementation can improve menstrual problems, dysmenorrhea and premenstrual syndrome in adolescents

Bahrami, A, Avan, A, Sadeghnia, HR, Esmaeili, H, Tayefi, M, Ghasemi, F, Salehkhani, FN, Arabpour-Dahoue, M, Rastegar, A, Ferns, G, Bahrami-Taghanaki, H and Ghayour-Mobarhan, M Gynecological Endocrinology. ISSN 1473-0766 (Accepted)

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Dysmenorrhea somewhat reduced
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Vitamin D has a crucial role in female reproduction, possibly through its effects on calcium homeostasis, cyclic sex steroid hormone fluctuations, or neurotransmitter function. We have assessed the effects of vitamin D supplementation on dysmenorrhea and premenstrual syndrome (PMS) in adolescents. In this study, 897 adolescent girls living in Mashhad and Sabzevar, Iran, received 9 high-dose vitamin D supplements (as 50000 IU/ week of cholecalciferol) and were followed up over 9 weeks. We evaluated the effect of vitamin D supplementation on individuals in 4 categories: those with only PMS; individuals with only dysmenorrhea; subjects with both PMS and dysmenorrhea and normal subjects.

The prevalence of PMS after the intervention fell from 14.9% to 4.8% (P<0.001).
Similar results were also found for the prevalence of subjects with dysmenorrhea (35.9% reduced to 32.4%), and in subjects with both PMS and dysmenorrhea (32.7% reduced 25.7%). Vitamin D supplementation was associated with a reduction in the incidence of several symptoms of PMS such as backache and tendency to cry easily as well decrement in pain severity of dysmenorrhea (P<0.05). High dose vitamin D supplementation can reduced the prevalence of PMS and dysmenorrhea as well has positive effects on the physical and psychological symptoms of PMS.

URI: http://sro.sussex.ac.uk/id/eprint/72540


Created by admin. Last Modification: Thursday September 23, 2021 12:59:35 GMT-0000 by admin. (Version 9)

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ID Name Comment Uploaded Size Downloads
11645 Dysmenorrhea.jpg admin 23 Mar, 2019 75.93 Kb 844
11644 PMS T2.jpg admin 23 Mar, 2019 57.48 Kb 786
11643 PMS 50,000.pdf admin 23 Mar, 2019 499.32 Kb 782