Metastatic Melanoma survived 2X longer if adequate level of Vitamin D – July 2023

---

From: CureToday July 2023

• “Among the study’s 200 participants with inoperable, locally advanced or metastatic melanoma who all received anti-PD-1 immunotherapy via Opdivo (nivolumab) or Keytruda (pembrolizumab), the objective response rate (ORR) among patients with low vitamin D levels which were not supplemented was 36.2%_ , while the response rate was 56%__ for patients with either normal baseline levels of vitamin D or those who obtained normal levels via supplementation, according to the study.”
• “The study — which was conducted by a team of Polish researchers and the results of which were published in the journal Cancer — also found that patients with normal vitamin D levels had a median progression-free survival (PFS, the time a patient lives without the disease spreading or becoming worse) of 11.25 months, nearly double the duration of the 5.75-month median PFS among patients with low levels of vitamin D.”

---

45+ VitaminDWiki pages with MELANOMA in title

This list is automatically updated

---

VitaminDWiki - Metastatic Cancer probably reduced by vitamin D - many studies

---

VitaminDWiki – Cancer category contains:

• Cancer 284 items Overview Cancer and vitamin D
• Cancer and Vitamin D - many studies
• After Cancer Diagnosis 110 items
• Bladder Cancer 27 items
• Breast Cancer 252 items Overview Breast Cancer and Vitamin D
• Colon Cancer 141 items Overview Cancer-Colon and vitamin D
• Leukemia 19 items
• Liver Cancer 17 items
• Lung Cancer 54 items Overview Lung cancer and vitamin D
• Lymphoma Cancer 25 items
• Other Cancer 66 items
• Ovarian Cancer 25 items
• Pancreatic Cancer 55 items
• Prostate Cancer 101 items Overview Prostate Cancer and Vitamin D
• Skin Cancer 121 items Overview Suntan, melanoma and vitamin D
• Childhood Cancers - Vitamin D can help - many studies
• Easiest way to treat cancer – take Vitamin D – Nov 2022
• 13 Cancers are helped by Vitamin D – Biobank July 2023
• 2X increase of 14 cancers in non-seniors in 20 years (low vitamin D) – Sept 2022
• Vitamin D prevents and treats cancer in many ways – May 2021
• Those with recent cancer diagnosis had 7X increased risk of COVID-19 (more if A-A )- Dec 2020
• Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
• Cancer incidence and mortality is decreased if 40-60 ng of Vitamin D – April 2019
• 8 ways that Cancer might be prevented by Vitamin D - June 2019
• Cancer stem cells and Vitamin D - many studies
• Vitamin D Reduces Cancer Risk - Why Scientists Accept It but Physicians Do Not - Feb 2019
• Overview of Vitamin D Actions in Cancer – 31 page chapter in a book – 2018
• Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
• Diagnosed with breast cancer – take vitamin D to cut chance of death by half – July 2018
• Melanoma 25 X more likely if low vitamin D – Feb 2018
• Better Cancer survival if higher vitamin D a decade earlier (esp. Melanoma, Kidney, Prostate)– Aug 2018

Cancers get less Vitamin D when there is a poor Vitamin D Receptor

• Vitamin D Receptor pages in VitaminDWiki with CANCER in title 86 as of July 2023
• Cancer and the Vitamin D Receptor, a primer – Sept 2017
• Vitamin D Receptor (Cancers OR Viruses) - many studies
• Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016
• Cancer (general) and VDR 23 articles
• Breast Cancer and VDR 22 articles
• Colon Cancer and VDR 13 articles
• Prostate Cancer and VDR 7 articles
• Skin Cancer and VDR 10 articles
  • Note some Health problems, such as some Cancers, protect themselves
    by actively reducing Receptor activation