- Vitamin K Intake in Chronic Stroke: Implications for Dietary Recommendations - Oct 2020
- Vitamin K2—a neglected player in cardiovascular health: a narrative review - Oct 2021
- Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review - 2020
- VitaminDWiki – Overview Vitamin K contains
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26 studies in both categories Cardiovascular and Vitamin K - VitaminDWiki -
3 studies in both categories Stroke and Vitamin K - 19+ VitaminDWiki pages with CALCIFICATION in the title
Vitamin K Intake in Chronic Stroke: Implications for Dietary Recommendations - Oct 2020
Nutrients 2020, 12(10), 3059; https://doi.org/10.3390/nu12103059
by Chad Wessinger,Charlene Hafer-Macko andAlice S. Ryan *
VA Research Service, Department of Medicine, Division of Gerontology and Geriatric Medicine at the University of Maryland School of Medicine, and the Baltimore VA Medical Center Geriatric Research, Education and Clinical Center (GRECC), VA Maryland Health Care System, Baltimore, MD 21201, USAPrevious research has identified a possible association between vitamin K intake and cardiometabolic disease. This could mean that the assessment of vitamin K intake is a meaningful tool when monitoring individuals with preexisting cardiovascular disease. Sixty chronic stroke survivors (men and women, body mass index (BMI) 30.36 ± 6.61 kg/m2, age 61.7 ± 7.2 years) completed food records which were analyzed for energy, macronutrient, micronutrient, and food group servings. Participants were divided into two groups: below vitamin K recommendation (BEL, n = 49) and met vitamin K recommendation (MET, n = 11). Energy and macronutrient intake did not differ between groups (all p > 0.127). Vegetable intake was higher in the MET group (p = 0.0001). Vitamin K intake was higher in the MET group (p = 0.0001). Calcium (p = 0.003), vitamin A (p = 0.007), and vitamin E (p = 0.005) intakes were higher in the MET group. There were no differences in sodium, potassium, vitamin D, vitamin C, and iron intakes between groups (all p > 0.212). In this sample of chronic stroke survivors, 82% reported consuming below the Dietary Reference Intake (DRI) for vitamin K. Given that the majority of this study population did not reach the DRI for vitamin K, it is advisable to promote the adequate intake of food rich in vitamin K. Further work is needed to determine the significance of low vitamin K intake in this population.
Clipped from PDF - predict future stroke
"More information is needed to better understand whether vitamin K intake could be used as an easy predictive marker for a secondary stroke. Due to vitamin K’s potential therapeutic interactions with various diseases, controlled supplementation may be indicated for individuals struggling to consume adequate amounts. Vitamin K supplementation should be considered as a potential adjuvant therapy to address atherosclerosis. Patients with cardiovascular disease risk factors and a desire to improve vascular condition should first discuss the benefits and risks of vitamin K supplementation with their medical care provider. These discussions are most relevant in patients on anticoagulants, such as warfarin or coumadin"
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Vitamin K2—a neglected player in cardiovascular health: a narrative review - Oct 2021
Open Heart - BMJ http://dx.doi.org/10.1136/openhrt-2021-001715
Essa Hariri1, http://orcid.org/0000-0002-7975-0861Nicholas Kassis1, Jean-Pierre Iskandar1, Leon J Schurgers2, Anas Saad3, Omar Abdelfattah3,4, Agam Bansal1, Toshiaki Isogai3, http://orcid.org/0000-0002-7442-4928Serge C Harb1 and Samir Kapadia 3 kapadis@ccf.org
Vitamin K2 serves an important role in cardiovascular health through regulation of calcium homeostasis. Its effects on the cardiovascular system are mediated through activation of the anti-calcific protein known as matrix Gla protein. In its inactive form, this protein is associated with various markers of cardiovascular disease including increased arterial stiffness, vascular and valvular calcification, insulin resistance and heart failure indices which ultimately increase cardiovascular mortality. Supplementation of vitamin K2 has been strongly associated with improved cardiovascular outcomes through its modification of systemic calcification and arterial stiffness. Although its direct effects on delaying the progression of vascular and valvular calcification is currently the subject of multiple randomised clinical trials, prior reports suggest potential improved survival among cardiac patients with vitamin K2 supplementation. Strengthened by its affordability and Food and Drug Adminstration (FDA)-proven safety, vitamin K2 supplementation is a viable and promising option to improve cardiovascular outcomes.
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Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review - 2020
Claire R. Palmer,ab Lauren C. Blekkenhorst,bc Joshua R. Lewis,bcd Natalie C. Ward, ORCID logo ce Carl J. Schultz,cf Jonathan M. Hodgson,bc Kevin D. Croft ORCID logo a and Marc Sim ORCID logo *bc
Food & Function Issue 4, 2020 DOI https://doi.org/10.1039/C9FO02321FCardiovascular disease is the leading cause of death and disability worldwide. Recent work suggests a link between vitamin K insufficiency and deficiency with vascular calcification, a marker of advanced atherosclerosis. Vitamin K refers to a group of fat-soluble vitamins important for blood coagulation, reducing inflammation, regulating blood calcium metabolism, as well as bone metabolism, all of which may play a role in promoting cardiovascular health. Presently, there is a lack of a comprehensive vitamin K database on individual foods, which are required to accurately calculate vitamin K1 and K2 intake for examination in epidemiological studies. This has likely contributed to ambiguity regarding the recommended daily intake of vitamin K, including whether vitamin K1 and K2 may have separate, partly overlapping functions. This review will discuss the presence of: (i) vitamin K1 and K2 in the diet; (ii) the methods of quantitating vitamin K compounds in foods; and (iii) provide an overview of the evidence for the cardiovascular health benefits of vitamin K in observational and clinical trials.
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VitaminDWiki – Overview Vitamin K contains
Vitamin K2 is similar to D3 in many ways
- Both vitamins were initially confused with its lesser form (D2 ==> D3, K1 ==> K2)
- Both vitamins appear to influence health in large number of ways
- Both vitamins in the body are about 1/10 that of a century ago
Example: Grass-fed beef has a lot more K2, D3, and Magnesium - Need very little of both vitamins: <1 milligram daily
- When Vitamin D3 is increased, it appears that Vitamin K2 should also be increased
- Vitamin K2 understanding and research is about 20 years behind that of Vitamin D3
One of the reasons: [https://www.perplexity.ai/search/is-there-a-vitamin-k2-blood-te-vVTdLPwcTFyi1Z_PM8yvTw|No simple blood test for K2 as of Dec 2024]
VitaminDWiki -
26 studies in both categories Cardiovascular and Vitamin K This list is automatically updated
- Vitamin K, cardiovascular health, and stroke - many studies
- Bone loss results in blood vessel plaque if low Vitamin K2, less bone loss if high K2– April 2021
- Cardiovascular Disease prevented by Vitamin K2-4 when enough is used – RCT review Sept 2020
- Calcium Supplementation is OK provided you also take Vitamin K – Feb 2019
- Vitamin K reduces calcification (reported yet again) – Feb 2019
- Vitamin K (across all dose sizes and types) decrease Vascular Stiffness – meta-analysis - Dec 2018
- Vitamin D and Vitamin K together fight CVD Part 1- Pizzorno
- Vitamin K, Cardiovascular and interactions with Vitamin D and Vitamin A – Pizzorno July 2018
- Mortality associated with Vitamin K insufficiency (PREVEND Study) – Nov 2017
- Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
- Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
- Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
- Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT July 2017
- Fast blood flow 6.8 X more likely if high vitamin D AND high vitamin K – Aug 2017
- Low Vitamin K2 is as risky as smoking for heart disease - Oct 2016
- Cardiovascular death: 9 percent due to hypertension or air pollution, 7 percent: low Vitamin K2 or smoking – Oct 2016
- Decreased need for warfarin after Vitamin D levels optimized – RCT May 2016
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- The health benefits of vitamin K – Oct 2015
- If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT May 2015
- Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
- Hypothesis: Vitamin K will reduce prostate blood vessel problems – Jan 2015
- Increased Vitamin K2 reduces the problems of excess Calcium – Nov 2013
- Cholesterol, Vitamins D3 and K2, heart disease, sulfates, LDL, – Masterjohn Interview Jan 2013
- Soft Bones, Hard Arteries, Vitamin D, Vitamin K2 and antibiotics – Sept 2012
- Low Vitamin D and Vitamin K: brittle bones and hardened arteries – LEF Sept 2010
VitaminDWiki -
3 studies in both categories Stroke and Vitamin K This list is automatically updated
- Vitamin K, cardiovascular health, and stroke - many studies
- Stroke is strongly associated with Calcification of cerebral arteries (perhaps low Vitamin D, Vitamin K, Mg…) – March 2018
- Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
19+ VitaminDWiki pages with CALCIFICATION in the title
This list is automatically updated
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