Vitamin D loading dose (stoss therapy) proven to improve health

Randomized Controlled Trials include

• Vitamin D reduced depression – single 300,000 IU – RCT Aug 2020
• 3X less Septic Shock in children with sepsis getting 150,000 IU of Vitamin D - RCT June 2020
• Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT March 2020
• Several Diabetic pains reduced by injection of 300,000 IU of Vitamin D – RCT Feb 2020
• ICU adults getting 540,000 IU of Vitamin D were 2X more likely to be alive 30 days later – RCT June 2019
• Vitamin D loading dose of 300,000 IU for children – 3 weeks with capsules, biscuits, injection – RCT Aug 2018
• Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
• 18 fewer hospital days if given 500,000 IU of vitamin D while ventilated in ICU – RCT June 2016
• Inflammation reduced by a single dose of Vitamin D (200,000 IU) – RCT Jan 2016
• 500,000 IU of vitamin D cut in half the hospital days following a lung failure – RCT 2015
• Elderly Vitamin D Loading Dose of 500,000 IU is safe and effective – RCT 2009

NOT Randomized Controlled Trials

• 400,000 IU of vitamin D reduced adult pain and improved quality of life – March 2014
• ICU survival increased with vitamin D single 540K IU loading dose - JAMA Sept 2014
• Healthy in Seven Days - Loading dose of Vitamin D – book 2014
• Vitamin D during pregnancy – single 200,000 IU similar to daily 5,000 IU – April 2020
• Intensive Care (ICU) helped by Vitamin D – review of past and on-going studies – Dec 2018
• Vitamin D loading doses reduce ICU mortality by 30 percent – meta-analysis April 2017

Injection

• Injection category listing has 62 items along with related searches
• ICU death rate reduced 3X when a vitamin D injection changed the PTH – Nov 2015
• Vitamin D injection lasts longer and has bigger response than weekly oral – Jan 2017

Injection and Randomized Controlled Trials

• Childhood asthma problems eliminated for months by 600,000 IU of Vitamin D injection – June 2017
• 10 fewer days of ICU Mechanical Ventilation 300,000 IU injection of vitamin D – RCT March 2019
• Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT July 2017
• Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018
• Pregnancies helped a lot by Vitamin D (injection then 50,000 IU monthly) – RCT May 2018

Injection is especially good for those with poor guts

• Vitamin D injection is far better than oral for diabetics (poor gut) – RCT March 2017 RCT
• Ulcerative colitis treated by injection of 300,000 IU of vitamin D – RCT July 2016 RCT
• Neuropathy - 5X more had a good Quality of Life after 600,000 IU of Vitamin D - 2017
  • Note: ~1/2 of COVID-19 hospitalizations have poor guts

See also in VitaminDWiki

• Overview Loading of vitamin D
• Vitamin D restoration then monthly was the most popular dosing by trials – Nov 2018
• Loading Dose of Vitamin D category listing has 200 items along with related searches
• Intervention - non daily category listing has 261 items along with related searches
• Consensus Vitamin D category listing has 68 items along with related searches
• Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019
• Need 40 to 60 ng of Vitamin D – 48 scientists call for action – 2015
• 4,000 IU of Vitamin D is OK - 19 organizations agree - 2018
• 372 types of vitamin D prescriptions in France, 200,000 IU was the most popular – Oct 2013
• Trauma and Surgery category listing has 333 items along with related searches
• Intensive Care (ICU) helped by Vitamin D – review of past and on-going studies – Dec 2018
• Hospital ICU added high dose vitamin D - malpractice lawsuit costs dropped from 26 million dollars to ZERO - Oct 2016

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Page created June 2020

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