Pages tagged with "cyp"

92 pages, most important first (overviews, then meta-analyses, then RCTs, then newest). Combine with another topic

• Vitamin D Cyp gene: VitaminDWiki summary
• CYP24A1 gene and Vitamin D - many studies
• CYP2R1 gene reduces response to Vitamin D - many studies
• Oral cancer risk from smoking: 3X less if good CYP24A1 gene, 3X higher if poor Receptor gene - meta-analysis
• Vitamin D gene (CYP24A1) changes decrease breast and pancreatic cancers – meta-analysis
• CYP2R1 gene probably responsible for low vitamin D response – RCT
• Poor CYP genes affect Vitamin D and several other systems in the body
• Changes in CYP3A4 gene affects Vitamin D, health, reactions to some drugs, etc
• Breast Cancer far more likely in the sister having poor Vitamin D binding protein or poor CYP2R1 gene
• Increased risk of various cancers if poor vitamin D genes (Binding Protein and CYP27B1)
• CYP24A1, which blocks Vitamin D, is restored by Curcumin, Resveratrol, Glutathione, etc
• Vitamin D gene: CYP11A1
• Hypothesis: Circadian Rhythm and Vitamin D are associated via CYP11A1 - Dec 2025
• CYP27B1
• Colon Cancer protects itself by changing the VDR and CYP3A4 genes
• Vitamin D levels massively changed by CYP3A4 gene (drugs such as Ivermectin and anti-epileptics)
• Suicide attempts by males 3.7 X more likely if poor Vitamin D gene (CYP24A1)
• CYP27A1
• Obese children have poor vitamin D genes (CYP27A1, CYP2R1, CYP27B1)
• Vitamin D suppressed by Roundup and Genes - CYP2R1, CYP24A1, CYP450 etc.
• Suppression of CYP24A1 gene got more Vitamin D to cells to fight Breast Cancer
• Schizophrenia associated with low Vitamin D and CYP2R1, CYP27B1, and CYP24A1
• Prostate Cancer associated with various genes, including Vitamin D Receptor and CYP24A1
• Acupuncture of scalp activates Vitamin D genes CYP27a1, CYP27b1, and CYP24a (rats with strokes)
• Autoimmune diseases and poor Vitamin D genes – GC, CYP2R1, CYP27B1, and VDR
• Cancers are sometimes associated with poor CYP24A1 gene (Vitamin D) (Bladder Cancer in this case)
• COVID maximum downregulation of Vitamin D receptor and CYP27B1 resulted in death
• Miscarriage (Recurrent Spontaneous) associated with poor CYP27B1 gene
• Miscarriage 70 percent more likely if low vitamin D (see also data on CYP27B1)
• Rare mutation of CYP24A1 gene results in Vitamin D accumulating
• Vitamin D accumulation in 1 in 300 people due to gene (CYP24A1) can cause Calcium problems
• Vitamin D non-responders may have one or more poor genes: GC, LIPC, CYP24A1, and PDE3B
• Prostate Cancer – Vitamin D – CYP27B1 – CYP24
• Get Multiple Sclerosis while younger if have a poor CYP24A1 vitamin D gene
• Breast Cancer chemotherapy improved if able to suppress a vitamin D gene (CYP24A1)
• No response to vitamin D 7X more likely if poor CYP24A1 or VDBP genes
• Poor CYP2R1 gene reduces blood response to Vitamin D supplementation
• Vitamin D resistant genes (CYP24A1, SMRT, SNAIL)
• Lupus associated with another poor vitamin D gene (CYP27B1 – in addition to low Vitamin D and poor VDR)
• Neuro problems (AD, PD, MSA) associated with poor vitamin D genes (CYP27A1, CYP27B1)
• Increased Phosphorus increases Vitamin D getting to cells (CYP24A1, pigs)
• Poor Vitamin D gene activation that results in rickets etc, (CYP27B1: 1 in 30 people in a region of Quebec)
• Poor genes (DBP, CYP24A1, CYP2R, etc.) restrict Vitamin D to cells, increasing COVID hospitalization
• Every Parkinson’s brain had a gene modification that limited how much vitamin D was available (CYP27B1)
• Gene mutations which restrict Vitamin D activation (CYP27B1) results in many health problems
• Vitamin D Metabolite Profiling and genes (CYP24A1, CYP27B1)
• COVID-19 cytokine storms perhaps better stopped by the CYP11A1 Vitamin D pathway
• High-fat diet reduces CYP2R1 gene needed to make semi-activated vitamin D (mice)
• CYP2R1 (vitamin D 25-hydroxylase ) semiactivates vitamin D in many places in the body
• Breast cancer and Vitamin D receptors, CP27B1, and CYP24A1
• COVID-19 5X worse if poor Vitamin D gene (CYP2R1)
• Kidney Stones are related to poor genes – example of CYP24A1 (Vitamin D)
• GC, CYP2R1 and DHCR7 genes associated with low vitamin D levels in China – 2012, 2013
• 3X higher risk of oral cancer if CYP27B1 and CYP24A1 genes were different
• Response to Vitamin D varied by 12 ng due to gene variants (CYP2R1)
• Hypothesis: Obesity reduces Vitamin D production by repressing CYP2R1 gene in liver and fat tissue
• Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1
• CYP2R1 mutations also cause vitamin D-deficient rickets
• CYP2R1 gene problem increases Multiple Sclerosis risk by 1.4X
• Hypertension 2X more likely if poor CYP24A1 vitamin D gene (China)
• GC and CYP2R1 genes associated with higher summer vitamin D levels
• Genes (CYP2R1 and GC) which restrict the amount of Vitamin D which gets into bloodstream
• CYP2R1 and GC variations decrease vitamin D response – PHD thesis
• Fasting and Diabetes both reduce Vitamin D activation (CYP2R1 in rodents)
• Acute Coronary Syndrome is associated with poor Vitamin D genes (CYP27B1, CYP24A1)
• Increased risk of weight gain when gene restricts Vitamin D getting to tissues (CYP24A1 in this case)
• Lungs with cystic fibrosis fail to activate vitamin D (poor CYP27B)
• Lung Cancer (NSLC) more lethal if poor Vitamin D gene ( CYP2R1)
• Genes such as CYP27B1, CYP24A1 and Vitamin D – JAMA
• Mutation of Vitamin D gene (CYP27B1) is strongly tied to MS
• Colon cancer 30 percent more likely if problems with Vitamin D genes CYP24A1 or CYP27B1
• UVB increases vitamin D even if poor kidney by changing CYP27B1 genes in skin
• Lung cancer – reduced deaths if have a good vitamin D gene (CYP27B1)
• CYP27B1 gene decreases kidney production of active vitamin D
• ALS associated with poor CYP27B1 gene (not seen by Vitamin D blood test)
• Type II diabetes 2 X more likely if poor Vitamin D Gene (CYP27B1)
• CYP24A1 gene in cancer cells may actually remove vitamin D from the blood
• Hepatitis C 1.4X more likely if poor CYP24A1 gene
• Natural pregnancy 4X more likely if sperm had a lot of CYP24A1
• CYP24A1 gene mutation is a cause of rare infant vitamin D toxicity
• Mutations in CYP24A1 gene (vitamin D) associated with kidney problems
• Vitamin D insufficiency was 3.7 X more likely if CYP2R1 gene variation
• Activation (methylation) of CYP2R1 and CYP24A1 predict response to dose of vitamin D
• If Lupus in family – 5 times more likely to get Lupus if low vitamin D and poor CYP24A1
• Maternal diabetes with poor Vitamin D gene (CYP24A1) increases risk of diabetes in female offspring by 40 percent
• Calcium problems associated with CYP24A1 (a Vitamin D gene)
• Breast Cancer rate reduced 72 percent by vitamin D gene polymorphism CYP24A1
• NB UVB increased vitamin D levels while decreasing psoriasis and CYP27A1
• Response to vitamin D related to DBP and CYP2RI genes
• Mice lacking CYP2R1 enzyme activate about half of much vitamin D
• CYP24A1 gene, kidney disease, and vitamin D
• Novel vitamin D gene regulation – CYP21A2