Vitamin D fails to prevent type 2 diabetes in large study
The actual study $40 million
Note: Diabetes and pre-diabetes are associated with poor guts
Since the start of this trial (2013) there have been many proven ways to deal with the restrictions of a poor gut
1) Use the same total amount of Vitamin D, but less frequently - the higher gradient gets thru better
2) Use more vitamin D daily
3) Use a probiotic to deal with the gut problem
4) Use a gut-friendly form of Vitamin D - there are more than a dozen types
5) Increase the response to Vitamin D by using Omega-3 and/or Magnesium
Avoid the poor gut
6) Use an injection
7) Use UV or sun
8) Use topical Vitamin D
The current failed trial was probably unaware of any of the above proven solutions
4,000 IU orally daily, no probiotic, no Magnesium, no Omega-3
Note: The pre-diabetic subgroup which started with < 12 ng of Vitamin D were 62% less likely to get diabetes
See also VitaminDWiki
Non daily
- Prediabetes both prevented and treated by monthly Vitamin D, etc.
- Insulin resistance helped with 50000 IU of vitamin D weekly – Feb 2013
- Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks – Nov 2014
- Better than Daily category listing has
33 items along with related searches Probiotic
Not oral
- Vitamin D injection is far better than oral for diabetics (poor gut) – RCT March 2017
- Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT - Jan 2017
Omega-3, Mg, etc
- Vitamin D and Omega-3 may treat Type 1 Diabetes – RCT 2024
- Magnesium is associated with prevention and treatment of Diabetes – Meta-analysis Aug 2016
Getting Vitamin D into your body has the following chart
Getting Vitamin D into your body has a section on poor digestion
If poorly functioning gut
Bio-D-Mulsion Forte – especially made for those with poorly functioning guts, or perhaps lacking gallbladder
Sublingual – goes directly into the bloodstream
Fat-soluble Vitamins go thru the slow lymph system
you can make your own sublingual by dissolving Vitamin D in water or use nano form
Oil: 1 drop typically contains 400 IU, 1,000 IU, or 4,000 IU, typically not taste good
Topical – goes directly into the bloodstream. Put oil on your skin, Use Aloe vera cream with Vitamin D, or make your own
Vaginal – goes directly into the bloodstream. Prescription-only?
Bio-Tech might be useful – it is also water-soluble
Vitamin D sprayed inside cheeks (buccal spray) - several studies
and, those people with malabsorption problems had a larger response to spray
Inject Vitamin D quarterly into muscle, into vein, or perhaps into body cavity if quickly needed
Nanoparticles could be used to increase vitamin D getting to the gut – Oct 2015
Poor guts need different forms of vitamin D has the following
Guesses of Vitamin D response if poor gutBio Form Speed Duration 10 Injection ($$$)
or Calcidiol or CalcitriolD - Slow
C -FastLong 10 Sun/UVB Slow Long 10 Topical
(skin patch/cream, vagina)Slow
Fast nanoNormal 9 Nanoemulsion -mucosal
perhaps activates VDRFast Normal 9? Inhaled (future) Fast Normal 8 Bio-D-Mulsion Forte Normal Normal 6 Water soluble (Bio-Tech) Normal Normal 4 Sublingual/spray
(some goes into gut)Fast Normal 3 Coconut oil based Slow Normal 2 Food (salmon etc.) Slow Normal 2 Olive oil based (majority) Slow Normal 10= best bioavailable, 0 = worst, guesses have a range of +-2
Speed: Fast ~2-6 hours, Slow ~10-30 hours
Duration: Long ~3-6 months, Normal = ~2 months
Titles of some of the web reports of this study
NIH-Funded Trial Finds Vitamin D Does Not Prevent Type 2 Diabetes In People At High Risk
Vitamin D3 Supplementation Fails to Significantly Lower Diabetes Risk in Patients with Pre-diabetes
D2d — No Defense against Diabetes
NIH-funded trial finds vitamin D does not prevent type 2 diabetes in people at high risk
D2d: Vitamin D Doesn't Stop Diabetes in Those With Prediabetes
Maine Researcher: ‘Excess Enthusiasm’ For Vitamin D Tamped Down By New Study
Vitamin D Supplements Don't Lower Type 2 Diabetes Risk, Study Suggests
Vitamin D Doesn't Halts The Progression Of Type 2 Diabetes In Patients With Prediabetes
Vitamin D Supplements Do Not Reduce Type 2 Diabetes Risk Significantly
Vitamin D Supplementation Did Not Prevent Type 2 Diabetes in Large Trial
Vitamin D does not prevent type 2 diabetes in people at high risk5546 visitors, last modified 04 Nov, 2019,