Health Problems and Vitamin D - association, prevention, and treatment

Better health is ASSOCIATED with more Vitamin D

Data from Grassroots Health

derived from Grassroots 2013
Pregnancy problems reduced GRH 2015

Mortality reduced

see page http://is.gd/lowddeath

Cancers and Mortality

VitaminDWiki page 6544

Survival of Head and Neck Cancers

Survival of head and neck cancers VDW #8128

Asthma is worse with lower Vitamin D

The worse the bronchial asthma, the lower the vitamin D – Jan 2017

20 ng of Vitamin D stops Rickets,
but many health problems need much more

Vitamin D levels needed at is.gd/neonate_vitD

More likely to survive Heart Failure

see wikipage http://www.vitamindwiki.com/tiki-index.php?page_id=2381

The relationship is far more than an association
Intervention has proven that Vitamin D prevents/treats 80+ health problems
Intervention = take some and see what happens

Proof that Vitamin D Works - list of health problems as of Aug 2017

Most are proven by Randomized Controlled Trials
Hypertension, Cardiovascular, Back pain, Diabetes, Influenza, Falls, Hip Fractures, Breast Cancer, Multiple Sclerosis, Raynaud's pain, Menstrual Pain, C-section and pregnancy risks, Low Birth Weight, Chronic Kidney Disease, Cystic Fibrosis, Rheumatoid Arthritis, TB, Rickets, Respiratory Tract Infection, Lupus, Sickle Cell, leg ulcers, traumatic brain injury. Parkinson's Disease, Multiple Sclerosis, Congestive Heart Failure (Infants), Middle Ear Infection (Infants), Gingivitis, stronger senior muscles, antibiotic use in seniors, short Infants, Gestational Diabetes, heart pump better after the attack, Prostate Cancer, Asthma, Depression, Vitamin D in Breast Milk, Fibromyalgia, Chronic Hives, Cholesterol, Weight loss, COPD, Asthma, Quality of Life, Survive ICU, Restless Leg Syndrome, Hepatitis-C, Crohn's disease, Pre-term birth, Lupus, Cluster headaches, Autism. PreDiabetes, Weight loss; Sarcopenia = muscle loss; Growing Pains, Osteoarthritis, ALS, Vertigo, Warts, Metabolic Syndrome, Hay fever, Preeclampsia, Blood cell cancer, Irritable Bowel Syndrome, Urinary Tract Infection, Mite Allergy, Perinatal Depression, Vaginosis. Eczema, NAFLD, Preeclampsia, Knee Osteoarthritis, Tuberculosis, Ischemic Stroke, Sepsis, Trauma Deaths, Hemodialysis, Fatty liver - child, Fatigue

A few items from the proof table

Health Problem	Treat Prevent	Reduction by Vit D click for details	RCT = Random Controlled Trial * = link to additional RCT CT = Clinical Trial
Diabetes Type 2	T	62 %	RCT* CRP reduction, 4000 IU Injection is far better - RCT *,
Influenza	P	90 %	RCT *, 2000 IU
Falls	P	50%	RCT, 100,000 IU monthly RCT with Meals on Wheels 2016
Rickets	P	98 %	Turkey, 400 IU NOT RCT, given to all children
Raynaud's Syndrome	T	40 %	RCT, visual scale, 20000 IU Avg
Menstrual pain	P	76 %	RCT, 7000 IU Avg, PMS reduced by half
Pregnancy risks	P	50 %	RCT, 4000 IU
C-section, unplanned	P	50 %	RCT, 4000 IU, small study
Low birth weight	P	60 %	RCT * 1000 IU of D2
TB	P	60 %	RCT, 800 IU
Breast Cancer	P	60 %	RCT, 1100 IU (2007)
Rheumatoid Arthritis pain	T	40 %	RCT, 500 IU, added to prescription
Cystic Fibrosis	T	75 % 2nd study improved	RCT, pilot 4X fewer deaths 250,000 IU RCT, pilot 8,200 IU
Chronic Kidney	T	90 to 70 PTH	RCT, 3500 IU,
Respiratory Tract Infection	P	63 %	RCT, 4000 IU 1 year 2nd RCT: 2000/800 IU 3rd RCT 20,000 IU weekly
Lupus	T	zero flares	Loading then 100,000 IU monthly, RCT too
Sickle Cell	T	Less pain	RCT, up to 100,000 IU/week
Traumatic Brain Injury	T	2X	RCT, 20,0000 IU/day with progesterone
Multiple Sclerosis	P	68%	RCT, 7100 IU prevent pre-MS ==> MS
Congestive Heart Failure	T	90 %	RCT, 1000 IU infants (also: Adults, not RCT)
Middle Ear Infection	P	30 %	RCT, 1000 IU infants
Gingivitis	T	88 %	RCT, 2000 IU
Muscle in seniors	T	17 % more muscle	RCT, 4000 IU
Antibiotic use when >70y	T	47 %	RCT, 60,000 IU monthly
Infants taller	Benefit	1 cm tall	RCT, 50,000 IU weekly, 8 weeks
Gestational Diabetes	T	Treated	RCT, 2 doses of 50,000 IU
After Heart Attack	T	+6% ejection fraction	RCT, 800,000 IU one time
Prostate Cancer	T	Fewer +cores	RCT, 4000 IU (2012)
Asthma	P T	Reduced symptoms	RCT, 60K IU/month; RCT 50K IU/week Meta-analysis of Asthma intervention Need good D at 4 weeks into preg.
Depression	T	Reduced	RCT, 300,000 IU injection RCT helped Prozac
Low vitamin D while breastfed	P	All infants > 20 ng	RCT, 5,000 IU
Fibromyalgia	T	Reduced	RCT, 30-48 ng RCT 50K IU/week
Hives, Chronic	T	Reduced 40%	RCT, 4000 IU added
Weight Loss	T	lost 5 more lbs	RCT, 2000 IU +diet +exercise
Multiple Sclerosis	T	95% were CURED	20,000 to 140,000 IU/day
Gestational Diabetes	P	40%	RCT * , 5,000 IU
Chronic Obstructive Pulmonary Disease	T	17X improvement	CT, 50,000 IU weekly RCT 100,000 IU monthly
Asthma	T	1/2 Asthma attacks	RCT >42 ng of vitamin D
Quality of Life (QoL)	T	Nursing Home QoL	CT, 4,000 IU in daily bread
Death of Critically Ill Patients	T	20% increase in survivability	RCT 540 K IU loading than 90K monthly
Pre-term birth	P	2.5X decrease, also: fewer c-section & better Apgar	RCT 2,000 IU India
Cluster headaches	T	CH eliminated in 60%	10,000 IU, Mg, Omega-3, etc
Weight loss: Overweight and Obese	T	12 lbs in 6 months	RCT 100,000 IU/month
Osteoarthritis pain	T	60% decrease	50,000 IU/weekly - NOT RCT, given to all
Amyotrophic Lateral Sclerosis	T	helped	2,000 IU - NOT RCT, given to all
Warts	T	80% eliminated injection	NOT RCT, given to all
Metabolic Syndrome	P	reduced 44% when VitD increased by 30 ng	NOT RCT, given to all
Hay fever	P	1,000 IU for 30 days	RCT
Preeclampsia	P	50,000 IU every 2 weeks	RCT
Irritable Bowel Syndrome	T	3,000 IU spray	RCT
Urinary Tract Infection	P	50% reduction	RCT 20,000 IU weekly
Perinatal depression (depression near birth)	T	50% reduction	RCT 2,000 IU for just a few weeks
Vaginosis	T	10X reduction	RCT 2,000 IU
Knee Osteoartiritis	T	Pain Reduced	RCT 60,000 IU monthly after loading dose
Stroke - Ischemic	T	Faster Recovery	RCT single 600,000 IU injection
Sepsis	T	Reduce ICU and Hospital length of stay by 7 days each	RCT 400,000 IU
Trauma deaths	T	50% fewer	Vitamin D & Glutamine NOT RCT, given to all

One pill every two weeks gives you all the vitamin D most adults need

50,000 IU Vitamin D pill every two weeks gets most (80%) health people to 40 ng

Is 50 ng of vitamin D too high, just right, or not enough

Health Problems
fought by Vitamin D (left column)

15,500+ pages in VitaminDWiki
Topic (# in topic)

Acne (20+ studies)

Attention Deficit Hyperactivity Disorder/ADHD (52+)

Alcohol (29+)

Allergy (120+) Overview

Amyotrophic Lateral Sclerosis/ALS (30+)

Alzheimer's (81+) Overview

Ankylosing Spondylitis (20+)

Antibiotics/Probiotics (92+) Overview

Asthma (145+) Overview

Atopic Dermatitis Overview (18+)

Autism (163) Overview

Vit. D Receptor (14+)

Transgender (19+)

Autoimmune (204+)

Systemic Sclerosis (10+)

Back Pain (44+)

Lumbar Degeneration (14+)

Bipolar Disorder (16+)

Bone - Health (313+)

BMD, Bone loss (55+)

Breathing (453+)

Hay Fever (20+)

Pneumonia (50+)

Respiratory (82+)

Burns/Wounds (30+)

Cancer (293+) Overview

After diagnosis (113+)

Bladder (28+)

Bone (8+)

Breast (259+) Overview

Child (16+)

Colon (145+) Overview

Endometrial (5+)

Gastric (9+)

Leukemia (19+)

Liver (17+)

Lung (55+) Overview

Lymphoma (26+)

Mg and Cancer (13+)

Melanoma (43+)

Multiple Myeloma (10+)

Metastatic (17+)

Other (66+)

Ovarian (26+)

Palliative Care (10+)

Pancreatic (58+)

Prostate (103+) Overview

Skin (121+) Overview

Survive (37+)

Thyroid (7+)

Cardiovascular (529+) Overview

Atherosclerosis (56+)

Atrial Fibrillation (20+)

Heart Failure (47+)

HRV (10+)

Omega-3 (38+)

Statins (80+)

Carpal Tunnel Syndrome (12+)

Cerebral Palsy (6+)

Cholesterol (52+) Overview

Chronic Fatigue (7) Overview

Cognitive (389+) Overview

Anesthesia ==> Cog

Brain (103+)

Delirium (9+)

Dementia (50+)

Mental Illness (300+)

Mental Stress (10+)

Colds/flu Overview

Concussions (25+)

Chronic obstructive pulmonary disease/COPD (17+)

COVID-19 (1300+)

Cystic Fibrosis (52+)

Dental (116+)

Fluoridation (16)

Periodontitis (32+)

Depression (268+)

Anxiety ( 11+)

Omega-3 (29)

SAD (9)

Diabetes (551+) Overview

Hemodialysis (41+)

Magnesium (27+)

Meta-analyses (39+)

Metabolic Syndrome + Mg

Neuropathy (15+)

Prediabetes (30+)

Red Meat (4+)

Retinopathy (8+)

Type 1 Diabetes (46+)

Vitamin D Receptor (23+)

Zinc (5+)

Diseases general (93+)

Ear (17+)

Otitis Media (10+)

Endometriosis (8+)

Epilepsy(17+)

Falls/Fractures (258+) Overview

Fatigue, Chronic Overview

Fertility/Sperm (142+)

Erectile Dysfunction (12+)

In Vitro Fert. (18+)

Testosterone (14+)

Fibromyalgia Overview

Fractures Overview

Ankle (16+)

Bone & Stress Fractures

Bone Mineral Density (28+)

Children (16+)

Hip Fractures (68+)

Vertigo (22+)

Frailty (16+)

Genetics (343+)

CYP24A1 (31+)

CYP24R1 (25+)

CYP27B1 (62+)

Epigenetics (18+)

Telomere (12+)

Vit D Binding (177+)

Vit D Receptor (517+)

Cancer in VDR (79+)

Gestational Diabetes (34+)

Gout (13+)

Gut (207+) Overview

Bariatric (15+)

Celiac (7+)

Clostridium difficile (9+)

Crohn's (38+)

IBD (28+)

IBS (18+)

Ulcerative Colitis (12+)

Hair (20+)

Alopecia Areata (8+)

Headache (48+)

Health - general (109+)

Human Immunodeficiency Virus/HIV (45+) Overview

Hives (10+)

Hypertension (165+) Overview

Pregnancy (41+)

Hyperparathyroid Overview

Immunity (273+)

Inflammation (175+)

CRP (19+)

Infection (141+)

Influenza Overview

Kidney (230+) Overview

Chronic Kidney (63+)

Dialysis (39+)

Kidney Stones (29+) Overview

Leprosy (16+)

Liver (102+) Overview

Hepatitis-B (12+)

Hepatitis-C (13+)

NAFLD (27+)

Lyme Disease (9+)

Lupus (78+)

Mental Illness (20+)

Mental Stress (5+)

Metabolic Syndrome (106+) Overview

Mortality (296+)

Multiple Sclerosis (412+) Overview

Genetics and Receptor (32+)

Virus (16+)

Muscle (113+)

Handgrip (12+)

Sarcopenia (30+)

Muscular Dystrophy (9+)

Myopia (17+)

Obesity (442+)Overview

Child & Youth (60+)

Vitamin D Receptor (16+)

Virus and Obesity (25+)

Weight Loss (31+)

Osteoarthritis (61+) Overview

Knee (26+)

Osteoporosis (220+) Overview

BMD (26+)

Pain - chronic (167+) Overview

Magnesium (13+)

Pancreatitis (20+)

Parkinson's (117+) Overview

Pneumonia (22+)

Pollution (31+)

Pregnancy (920+) Overview

Breastfed (38+)

Caesarean (15+)

Depression (21+)

Dark Skin (30+)

Gestational Diabetes (41+)

In Vitro Fert. (20+)

Iodine (28+)

Low Birth Weight (23+)

Magnesium (30+)

Miscarriage (38+)

Multiple Sclerosis (13+)

Omega-3 before and during (49+)

PCOS (15+)

Preeclampsia (63+)

Preterm (156+)

Preterm - Omega-3 (13+)

Stillbirth (12+)

Prostate - BPH (16+)

Psoriasis (72+)

Respiratory Tract Infection/RTI (8+)

Restless Legs Syndrome (15+)

Rheumatoid Arthritis (117+) Overview

Juvenile RA (9+)

Rickets (127+) Overview

Sarcopenia (28+)

Schizophrenia Overview

Sepsis (201+)

Shingles (15+)

Sickle Cell (20+) Overview

Skin (122+) Overview

Aging

Atopic Dermatitis(27+)

Hives

Vitiligo (8+)

Sleep (101+)

Sleep Apnea(12+)

Smoking (83+)

Spinal Cord (21+)

Spinal Surgery (13+)

Statins (40+)

Stroke (131+) Overview

Cognitive Impairment (15+)

Depression (9+)

Ischemic (21+)

Suicide (16+)

Thyroid/Parath. (82+) Overview

PTH (34+)

Trauma/Surgery (352+)

Bariatric surgery (12+)

Bone surgery (23+)

ICU & Loading Dose (69+)

Need Vit D (69+)

Ortho. & Hip (69+)

Sepsis (41+)

Transplant (31+)

Traumatic Brain Injury (24+)

Tuberculosis (125+) Overview

Urinary Tract Infection (15+)

Vertigo (18+)

Virus (1400+)

Air pollution

All studies

Bird Flu

Cardiovascular (19+)

Cancers after VAX (17+)

Child - years after VAX (11+)

Cognitive (10+)

Dengue (27+)

Epstein-Barr Virus (20+)

Excess Deaths (23+)

Hepatitis (29+)

Herpes or Shingles (13+)

Ivermectin (35+)

Long-COVID (72+)

Magnesium (60+)

Masks (11+)

Meta-analyses (40+)

Mononucleosis

Omega-3 (14+)

Pfizer (20+)

RSV (12+)

Ultraviolet light (16+)

Vaccination (198+)

Vitamin D (650+)

Vitamin D Receptor (31+)

Vitamin K

Zinc (32+)

Vision (112+)

Cataracts (13+)

Diabetic Retinopathy (8+)

Dry Eye (12+)

Glaucoma (8+)

Macular Degeneration (20+)

Myopia (20+)

Uveitis (10+)

People and Low Vitamin D

Infant/Child (854+)

Allergy (36+)

Cancer (13+)

Cerebral Palsy (15+)

Down Syndrome (5+)

Fracture, low energy (10+)

Growing Pains (10+)

Pneumonia (25+)

Preemie (25+)

Puberty early if low D (9+)

Respiratory (21+)

RSV (25+)

Tonsils (9+)

Vaccination (10+)

Virus (42+)

Military (27+)

Veterans (17+)

Prisoners (14+)

Seniors (430+) Overview

Aging (38+)

Essential Tremor (4+)

Frailty (20+)

Longevity (47+)

Nursing Homes (19+)

Sarcopenia (25+)

Urinary incontinence (15+)

Vertigo (22+)

Skin - Dark (460+) Overview

Pregnancies (30+)

Sports (277+) Overview

Exercise (68+)

Muscle (138+)

Traumatic Brain Inj. (24+)

Women (196+) Overview

Endometriosis (25+)

Incontinence (16+)

Menopause (17+)

PCOS

Premenstrual Syndrome (20+)

Uterine Fibroid (13+)

Yeast Infection

Youth (175+)

Early Puberty (15+)

Locations

World (14+)

Aust NZ (68+)

Africa (28+)

Europe (233+)

India (65+)

Iceland (40+)

Middle East (154+)

Orient (77+)

Russia (12+)

Scotland (20+)

Far from Equator (124+)

Click here to search the site
A list includes 290+ pages having many studies
# of studies as of Dec 11, 2024
short URL for this page = is.gd/dhealth