Does vitamin D status influence lumbar disc degeneration and low back pain in postmenopausal women? A retrospective single-center study
Menopause: May 2020 - Volume 27 - Issue 5 - p 586-592, doi: 10.1097/GME.0000000000001499
Xu, Hao-Wei MD; Yi, Yu-Yang MD; Zhang, Shu-Bao MD; Hu, Tao MD, PhD; Wang, Shan-Jin MD, PhD; Zhao, Wei-Dong MD; Wu, De-Sheng MD, PhD
Back Pain category starts with the following
- Low back pain 2X more likely if very low Vitamin D – meta-analysis Nov 2017
- Lumbar degenerative disc diseases might be fought by Vitamin D Receptor activation– many studies
- Back pain was found in one study to be relieved in 95% of patients by vitamin D
- Vitamin D treats many types of Chronic Pains
- Vitamin D improves bone health, which decreases back problems
- There are
44 items in the Back Pain category in VitaminDWiki - Magnesium also reduces back pain
- by reducing muscle tension and improving bones- Founder of VitaminDWiki found a combination including Vit D plus Mg to be great
Back Pain and Vitamin D Receptor studies
Genes were not considered in the current study
- Spinal disc degeneration 1.8X more likely if poor Vitamin D Receptor – mata-analysis Sept 2020
- Lumbar disc degeneration 30 percent more likely if poor Vitamin D Receptor – May 2019
- Lumbar Degenerative Disc Disease 3X more likely if poor Vitamin D Receptor – March 2018
- Disc Degeneration in women is 1.7X more likely if poor Vitamin D Receptor – meta-analysis Jan 2017
- Degeneration of lumbar disc 2.5 X more likely if poor Vitamin D receptor (not detected by test) Feb 2018
- Lumbar degenerative disc diseases might be fought by Vitamin D Receptor activation– many studies
- Spinal disc degeneration is associated with vitamin D receptor genes, and others – March 2013
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Objective:
To investigate the relationship between serum vitamin D concentration and lumbar disc degeneration (LDD) in postmenopausal women and the epidemiologic factors affecting low back pain (LBP).Methods:
Between July 2017 and December 2018, 232 participants were retrospectively enrolled. Serum concentrations of bone turnover markers were measured using electrochemiluminescence assays. Disc degeneration was evaluated using the Pfirrmann grading system. Other variables were assessed using relevant questionnaires.Results:
The mean age of the women was 65.6 ± 10.1 and their serum 25(OH)D concentrations were 19.38 ± 9.21 ng/mL. The prevalences of severe vitamin D deficiency (<10 ng/mL) and normal status (>30 ng/mL) were 12.9% and 12.5%, respectively. The severely deficient group had higher visual analog scale (VAS) scores for LBP (P = 0.002) and lower bone mineral density T scores (P = 0.004) than the other groups. Lower 25(OH)D concentration (<10 ng/mL) was significantly associated with more severe LDD in the lumbosacral region (L4-S1, L1-S1, P < 0.05), but less so in the upper lumbar region. There was an inverse relationship between vitamin D concentration and the severity of disc degeneration (L2-L3, L4-S1, L1-S1, P < 0.05). After adjustment for confounding factors, smoking, vitamin D deficiency, lack of vitamin D supplementation, high body mass index, and low bone mineral density T score were associated with higher incidence of moderate-to-severe pain in postmenopausal women (P < 0.05).Conclusions:
Vitamin D deficiency is associated with LDD and LBP in postmenopausal women. Specifically, a serum vitamin D concentration < 10 ng/mL is a marker of severe LDD and LBP. Smoking, severe vitamin D deficiency, lack of vitamin D supplementation, high body mass index, and osteoporosis are associated with a higher prevalence of moderate-to-severe pain.Printer Friendly Follow this page for updates3734 visitors, last modified 19 Sep, 2020, - Magnesium also reduces back pain