Proposal and validation of a quick question to rate the influence of diet in geriatric epidemiological studies on vitamin d.
Int J Vitam Nutr Res. 2013;83(4):254-8. doi: 10.1024/0300-9831/a000163.
Gaëlle Chevallereau1, Xavier Gleyses2, Laurène Roussel3, Sarah Hamdan4, Olivier Beauchet5, Cédric Annweiler6
1Medical School, University of Angers, UNAM, Angers, France;
2Medical School, University of Angers, UNAM, Angers, France;
3Medical School, University of Angers, UNAM, Angers, France;
4Medical School, University of Angers, UNAM, Angers, France;
5Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; UPRES EA 4638, University of Angers, UNAM, Angers, France;
6Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; UPRES EA 4638, University of Angers, UNAM, Angers, France;, and Robarts Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada Author information
BACKGROUND:
Diet is a major exogenous source of vitamin D. The objective of this analysis was to determine whether the yes/no answer to a simple question exploring diet
("Do you eat fatty fish at least once a week and/or eggs several times per week?")
could be associated with serum 25-hydroxy-vitamin D status among 261 older in- and outpatients (mean ± standard deviation, 83.5 ± 8.1 years).
METHODS:
Two groups were distinguished based on the binary yes/no answer. Hypovitaminosis D was defined as serum 25-hydroxyvitamin D ≤ 75 nmol/L.
RESULTS:
More participants with hypovitaminosis D answered "No" to the question on diet compared to their counterparts (p = 0.002). Answering "No" was associated with hypovitaminosis D (OR = 3.22, p = 0.001) after adjustment for potential confounders, with a positive predictive value = 79 %.
CONCLUSION:
A simple dietary question may identify older patients with hypovitaminosis D who should receive vitamin D supplements.
PMID: 25008016
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See also VitaminDWiki
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- 13 reasons why many seniors need more vitamin D (both dose and level) - July 2023 has the following
- Senior skin produces 4X less Vitamin D for the same sun intensity
- Seniors have fewer vitamin D receptor genes as they age
Receptors are needed to get Vitamin D in blood actually into the cells - Many other Vitamin D genes decrease with age
- Since many gene activations are not detected by a blood test,
more Vitamin D is often needed, especially by seniors - Seniors are indoors more than when they were younger
not as agile, weaker muscles; frail, no longer enjoy hot temperatures - Seniors wear more clothing outdoors than when younger
Seniors also are told to fear skin cancer & wrinkles - Seniors often take various drugs which end up reducing vitamin D
Some reductions are not detected by a vitamin D test of the blood
statins, chemotherapy, anti-depressants, blood pressure, beta-blockers, etc - Seniors often have one or more diseases that consume vitamin D
osteoporosis, diabetes, Multiple Sclerosis, Cancer, ... - Seniors generally put on weight as they age - and a heavier body requires more vitamin D
- Seniors often (40%) have fatty livers – which do not process vitamin D as well
- Reduced stomach acid means less Magnesium is available to get vitamin D into the cells
- Vitamin D is not as bioavailable in senior intestines
- Seniors with poorly functioning kidneys do not process vitamin D as well
- Glutathione (which increases Vitamin D getting to cells) decreases with age
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