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Elderly 3X more likely to have 30 ng of vitamin D if frequently eat fatty fish, eggs – Aug 2013

Proposal and validation of a quick question to rate the influence of diet in geriatric epidemiological studies on vitamin d.

Int J Vitam Nutr Res. 2013;83(4):254-8. doi: 10.1024/0300-9831/a000163.
Gaëlle Chevallereau1, Xavier Gleyses2, Laurène Roussel3, Sarah Hamdan4, Olivier Beauchet5, Cédric Annweiler6
1Medical School, University of Angers, UNAM, Angers, France;
2Medical School, University of Angers, UNAM, Angers, France;
3Medical School, University of Angers, UNAM, Angers, France;
4Medical School, University of Angers, UNAM, Angers, France;
5Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; UPRES EA 4638, University of Angers, UNAM, Angers, France;
6Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; UPRES EA 4638, University of Angers, UNAM, Angers, France;, and Robarts Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada Author information

BACKGROUND:
Diet is a major exogenous source of vitamin D. The objective of this analysis was to determine whether the yes/no answer to a simple question exploring diet
("Do you eat fatty fish at least once a week and/or eggs several times per week?")
could be associated with serum 25-hydroxy-vitamin D status among 261 older in- and outpatients (mean ± standard deviation, 83.5 ± 8.1 years).
METHODS:
Two groups were distinguished based on the binary yes/no answer. Hypovitaminosis D was defined as serum 25-hydroxyvitamin D ≤ 75 nmol/L.
RESULTS:
More participants with hypovitaminosis D answered "No" to the question on diet compared to their counterparts (p = 0.002). Answering "No" was associated with hypovitaminosis D (OR = 3.22, p = 0.001) after adjustment for potential confounders, with a positive predictive value = 79 %.
CONCLUSION:
A simple dietary question may identify older patients with hypovitaminosis D who should receive vitamin D supplements.

PMID: 25008016


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  1. Senior skin produces 3X less Vitamin D for the same sun intensity
  2. Seniors have fewer vitamin D receptor genes as they age
    Receptors are needed to get Vitamin D in blood actually into the cells
  3. Many other Vitamin D genes decrease with age
  4. Since many gene activations are not detected by a blood test,
    more Vitamin D is often needed, especially by seniors
  5. Seniors are indoors more than when they were younger
    not as agile, weaker muscles; frail, no longer enjoy hot temperatures
  6. Seniors wear more clothing outdoors than when younger
    Seniors also are told to fear skin cancer & wrinkles
  7. Seniors often take various drugs which end up reducing vitamin D
    Some reductions are not detected by a vitamin D test of the blood
    statins, chemotherapy, anti-depressants, blood pressure, beta-blockers, etc
  8. Seniors often have one or more diseases that consume vitamin D
    osteoporosis, diabetes, Multiple Sclerosis, Cancer, ...
  9. Seniors generally put on weight at they age - and a heavier body requires more vitamin D
  10. Seniors often (40%) have fatty livers – which do not process vitamin D as well
  11. Reduced stomach acid means less Magnesium is available to get vitamin D into the cells
  12. Vitamin D is not as bioavailable in senior intestines
  13. Seniors with poorly functioning kidneys do not process vitamin D as well
       Seniors category has 407 items