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Overview Pain and Vitamin D


24+ VitaminDWiki pages have both PAIN and RCT in their title

This list is automatically updated

Items found: 24
Title Modified
Muscle pain in obese women reduced by aerobic exercise plus 50,000 IU Vitamin D - RCT May 2021 27 Aug, 2023
Pain not reduced by 60,000 IU monthly vitamin D (need 50,000 IU weekly) – RCT Aug 2023 22 Jul, 2023
Raynaud's pain decreased with 600,000 IU monthly vitamin D – RCT May 2012 17 Jul, 2023
Menstrual Pain (PMS) reduced by vitamin D – RCT 2012, 2014, 2016 23 Sep, 2021
Several Diabetic pains reduced by injection of 300,000 IU of Vitamin D – RCT Feb 2020 25 Jul, 2020
Lower back pain treated by 600,000 IU of Vitamin D – RCT June 2019 28 Jun, 2019
Knee pain and depression reduced by monthly 50,000 IU vitamin D – RCT April 2018 21 Apr, 2018
Pain not relieved by monthly 100,000 IU of vitamin D (need 50,000 IU weekly) – RCT Feb 2018 02 Mar, 2018
Can burn pain be relieved by 4 g of Omega-3 and 2,000 IU of vitamin D – RCT due 2021 18 Oct, 2017
Long-term lower back pain greatly reduced by Magnesium - RCT 2013 29 May, 2017
Knee osteoarthritis pain reduced by 60,000 IU monthly vitamin D following loading dose – RCT Nov 2013 24 Dec, 2016
Raynaud's pain decreased with 20,000 IU daily average vitamin D – RCT May 2012 05 Dec, 2016
Less use of musculoskeletal pain drugs if get vitamin D (no dose information)– RCT Feb 2015 20 Nov, 2016
Menstrual Pain reduced by vitamin D – RCT Feb 2012 07 May, 2016
Back pain not relieved when vitamin D levels remained below 30 nanograms – RCT Nov 2015 04 Dec, 2015
Fibromyalgia pain reduced with vitamin D intervention that achieved 30-48 ng – RCT Feb 2014 05 Nov, 2015
Musculoskeletal pain reduced with 4,000 IU of vitamin D – RCT April 2015 05 Nov, 2015
Pain not reduced by vitamin D (only used 1,000 IU) - RCT Dec 2014 16 Jul, 2015
Breast Cancer medicine pain reduced with 4300 IU vitamin D – RCT June 2012 24 May, 2015
Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT Nov 2014 22 Nov, 2014
Dark skinned in Norway: 1000 IU vitamin D not enough to reduce pain – RCT Sept 2014 28 Sep, 2014
150,000 IU vitamin D reduced pain in immigrants – RCT Dec 2012 17 Sep, 2014
Pain reduction with 600,000 IU Vitamin D: RCT announced Dec 2013 06 Dec, 2013
Just 500 IU of vitamin D helped reduce rheumatoid arthritis pain - RCT Oct 2011 07 Sep, 2012

Chronic Pain
Fibromyalgia and Widespread

Rheumatoid Arthritis

Headache Pain

Dark Skin Pain

Other Pain

Image Image


Pain - chronic category has the following

163 items in category Chronic pain

See also


32 Items in both of the categories Pain and Intervention:


VitaminDWiki - Proof that Vitamin D Works (93+)

includes: Back Pain,   Raynaud's Pain,   Menstrual Pain,   Rheumatoid Arthritis,   Sickle Cell Pain,   Fibromyalgia   Knee pain   Growing Pain  Headache Pain
Note: Many pains are not treated by 1 pill every 2 weeks - they need 1 pill every week


Serious chronic pain list from Institute of Medicine (everyone is helped by Vitamin D

  • Migraine and other serious headaches,
  • Arthritis and other joint pain,
  • Endometriosis,
  • Irritable bowel syndrome,
  • Trauma or postsurgical pain
  • Lower-back pain,
  • Shingles,
  • Sickle-cell disease,
  • Heart disease (angina),
  • Cancer,
  • Stroke

Vitamin D and Chronic Pain] iHerb Nov 2013

The health Haven

  • People with inadequate vitamin D blood levels will need to take twice as much narcotic pain medication as those with adequate vitamin D for pain relief. So, while vitamin D does not cure chronic pain, it is an important adjuvant therapy to use in pain treatment management.
  • Research studies on vitamin D have shown that many types of fatigue and chronic pain are linked to vitamin D deficiency, including chronic musculoskeletal pain, fibromyalgia syndrome, osteoarthritis, migraine headaches, rheumatic pain and hyperesthesia.
  • 'For patients who do not respond to other therapy, vitamin D supplementation is recommended to alleviate or perhaps even resolve chronic fatigue and pain issues

Vitamin D - A Neglected 'Analgesic' for Chronic Musculoskeletal Pain- An Evidence-Based Review & Clinical Practice Guidance - 2008

Pain-Topics.org 2008, Author: Stewart B. Leavitt, MA, PhD
Medical Reviewers Bruce Hollis, PhD; Michael F. Holick, MD, PhD; Seth I. Kaufman, MD; Lee A. Kral, PharmD, BCPS; Paul W. Lofholm, PharmD, FACA; N. Lee Smith MD; James D. Toombs, MD; Winnie Dawson, RN, BSN, MA
 Download the PDF from VitaminDWiki.
Elderly Skin generates less Vitamin D Derived from chart in that study
Elderly skin generates less vitamin D


Pain relievers can extend duration of back pain - and sometimes turning it into a chronic pain - May 2022

Common Medications Can Prolong Back Pain, Study Says New York Times

  • "Guidelines from professional medical societies already say that people with back pain should start with nondrug treatments like exercise, physical therapy, heat or massage. Those measures turn out to be as effective as pain-suppressing drugs, without the same side effects."
  • Biobank stiudy found ...2,163 people with acute back pain, 461 of whom went on to have chronic pain. Those taking a nonsteroidal anti-inflammatory had nearly double the chance of developing chronic back pain as those taking other drugs or no drugs, the researchers found.
  • "An analysis of randomized clinical trials found that these drugs had almost no benefit over placeboes in reducing low back pain."

Study - Acute inflammatory response via neutrophil activation protects against the development of chronic pain PDF


People in pain having low vitamin D levels will benefit from supplementation - Oct 2017

Vitamin D in Pain Management - review
 Download the PDF from VitaminDWiki


See also web

Brief pain summary May 2016
The Opioid Epidemic We Failed to Foresee New York Times

I (Henry Lahore) sent the following comment to NYT

WOMEN'S PAIN IS DIFFERENT FROM MEN'S—THE DRUGS COULD BE TOO Wired Mag March 2019

  • Nothing about Vitamin D. Virtually all pain research has been on maile animals

Mercola Review of Acupuncture for pain relief Aug 2017 nothing about vitamin D

  • 2002 WHO review
  • 2004 of 29 studies found 50% reduction in pain levels
  • 2015 BBC Video
  • Recent acupuncture study discovered Nitric Oxide (NO) at the points

Alternatives to Drugs for Treating Pain NYT Sept 2017

  • Pain of headaches, back, sciatica, etc, are sometimes due to muscle tension.
  • Reducing the muscle tension thru relaxation (meditation, yoga, etc) often help
  • The article references include
    "Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians" - April 2017 full text online
    "Evidence-Based Evaluation of Complementary Health Approaches for Pain Management in the United States" May 2016 free PDF on-line
    Image
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    Personal note: They do not seem to mention additional ways I have found to eliminate various pains in 10 minutes.

Pain Factoids from the Body by Bill Bryson, 2019

  • Chronic pain has no purpose. It’s just a system gone wrong, in the same way that cancer is a system gone wrong. We now believe that many types of chronic pain are diseases in their own right, something quite separate from acute pain.”
  • The International Classification of Headache Disorders recognizes fourteen categories of headaches—migraine, trauma-induced headache, infection-induced headache, disorder of homeostasis, and so on.
  • According to the U.S. Institute of Medicine, part of the National Academy of Sciences, about 40 percent of adult Americans—100 million people—are experiencing chronic pain at any given moment.
  • Altogether chronic pain affects more people than cancer, heart disease, and diabetes combined.
  • Andrew Rice, a pain researcher at Imperial College London, told Nature in 2016, “The drugs we have relieve 50 percent of pain in somewhere between one in four and one in seven of the patients we treat. That’s for the best drugs.” In other words, some 75 percent to 85 percent of people get no benefit at all from even the best pain drugs, and those who do get benefit don’t usually get much.

Pain is associated with other categories: Intervention, 33, Osteoarthritis 9, Loading dose 7, Skin - Dark 7, Magnesium 7, Seniors 7, Sleep,7, etc

Back pain, 6, Cancer - after diagnosis, 5, Osteoporosis, 5 (as of Nov 2023)

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Overview Pain and Vitamin D        
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Attached files

ID Name Comment Uploaded Size Downloads
18858 Pain 60,000 month RCT.pdf admin 25 Nov, 2022 376.11 Kb 261
17601 chronic pain and pain relievers_CompressPdf.pdf admin 15 May, 2022 804.88 Kb 355
8971 VITAMIN D DEFICIENCY AND CHRONIC WIDESPREAD PAIN.pdf admin 20 Dec, 2017 135.21 Kb 4887
8581 Vitamin D and Pain.pdf admin 24 Oct, 2017 221.67 Kb 1335
8412 Mayo pain summary.jpg admin 11 Sep, 2017 72.12 Kb 4138
8411 Mayo Pain.jpg admin 11 Sep, 2017 26.26 Kb 3989
7883 Opioid addiction.jpg admin 28 Mar, 2017 30.38 Kb 4453
3151 Pain Topics vitamind June 2008.pdf admin 20 Oct, 2013 769.94 Kb 2998
2351 PAIN from GrassRoots survey.jpg admin 13 Apr, 2013 68.26 Kb 7710
2158 Pain - 2013 non specific.pdf admin 02 Mar, 2013 119.45 Kb 2426