Taking vitamin D for health problems has raised D levels a bit (child Arthritis this case) – July 2021

Higher concentrations of vitamin D in Canadian children with juvenile idiopathic arthritis compared to healthy controls are associated with more frequent use of vitamin D supplements and season of birth

Nutr Res. 2021 Jun 13;92:139-149. doi: 10.1016/j.nutres.2021.05.007
Sarah L Finch 1, Alan M Rosenberg 2, Anthony J Kusalik 3, Farhad Maleki 3, Elham Rezaei 3, Adam Baxter-Jones 3, Susanne Benseler 4, Gilles Boire 5, David Cabral 6, Sarah Campillo 7, Gaëlle Chédeville 7, Anne-Laure Chetaille 8, Paul Dancey 9, Ciaran Duffy 10, Karen Watanabe Duffy 10, Jaime Guzman 6, Kristin Houghton 6, Adam M Huber 11, Roman Jurencak 10, Bianca Lang 11, Ron M Laxer 12, Kimberly Morishita 6, Kiem G Oen 13, Ross E Petty 6, Suzanne E Ramsey 11, Johannes Roth 10, Rayfel Schneider 12, Rosie Scuccimarri 7, Elizabeth Stringer 11, Shirley M L Tse 12, Lori B Tucker 6, Stuart E Turvey 6, Michael Szafron 3, Susan Whiting 3, Rae Sm Yeung 12, Hassan Vatanparast 14, BBOP Study Group


juvenile idiopathic arthritis in VitaminDWiki

Items in both categories Rheumatoid Arthritis and infant-Child are listed here:

Now doctors need to learn to prescribe enough vitamin D to make a difference

A number of studies have demonstrated that patients with autoimmune disease have lower levels of vitamin D prompting speculation that vitamin D might suppress inflammation and immune responses in children with juvenile idiopathic arthritis (JIA). The objective of this study was to compare vitamin D levels in children with JIA at disease onset with healthy children. We hypothesized that children and adolescents with JIA have lower vitamin D levels than healthy children and adolescents. Data from a Canadian cohort of children with new-onset JIA (n= 164, data collection 2007-2012) were compared to Canadian Health Measures Survey (CHMS) data (n=4027, data collection 2007-2011). We compared 25-hydroxy vitamin D (25(OH)D) concentrations with measures of inflammation, vitamin D supplement use, milk intake, and season of birth. Mean 25(OH)D level was significantly higher in patients with JIA (79 ± 3.1 nmol/L) than in healthy controls (68 ± 1.8 nmol/L P <.05). Patients with JIA more often used vitamin D containing supplements (50% vs. 7%; P <.05). The prevalence of 25(OH)D deficiency (<30 nmol/L) was 6% for both groups. Children with JIA with 25(OH)D deficiency or insufficiency (<50 nmol/L) had higher C-reactive protein levels. Children with JIA were more often born in the fall and winter compared to healthy children. In contrast to earlier studies, we found vitamin D levels in Canadian children with JIA were higher compared to healthy children and associated with more frequent use of vitamin D supplements. Among children with JIA, low vitamin D levels were associated with indicators of greater inflammation.

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